Genomics and drug profiling of fatal TCF3-HLF−positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options U Fischer, M Forster, A Rinaldi, T Risch, S Sungalee, HJ Warnatz, ... Nature genetics 47 (9), 1020-1029, 2015 | 252 | 2015 |
Infection Exposure Is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility A Martin-Lorenzo, J Hauer, C Vicente-Duenas, F Auer, ... Cancer discovery 5 (12), 1328-1343, 2015 | 149 | 2015 |
Protein threading by recursive dynamic programming R Thiele, R Zimmer, T Lengauer Journal of Molecular Biology 290 (3), 757-779, 1999 | 75 | 1999 |
Prognostic profiling of the immune cell microenvironment in Ewing s Sarcoma Family of Tumors D Stahl, AJ Gentles, R Thiele, I Gütgemann Oncoimmunology 8 (12), e1674113, 2019 | 64 | 2019 |
New scoring schemes for protein fold recognition based on Voronoi contacts. R Zimmer, M Wö hler, R Thiele Bioinformatics (Oxford, England) 14 (3), 295-308, 1998 | 60 | 1998 |
The impact of TEL-AML1 (ETV6-RUNX1) expression in precursor B cells and implications for leukaemia using three different genome-wide screening methods Y Linka, S Ginzel, M Krüger, A Novosel, M Gombert, E Kremmer, J Harbott, ... Blood cancer journal 3 (10), e151-e151, 2013 | 58 | 2013 |
Next-generation-sequencing of recurrent childhood high hyperdiploid acute lymphoblastic leukemia reveals mutations typically associated with high risk patients C Chen, C Bartenhagen, M Gombert, V Okpanyi, V Binder, S Röttgers, ... Leukemia research 39 (9), 990-1001, 2015 | 45 | 2015 |
Next‐generation‐sequencing‐based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia C Chen, C Bartenhagen, M Gombert, V Okpanyi, V Binder, S Röttgers, ... Genes, Chromosomes and Cancer 52 (6), 564-579, 2013 | 43 | 2013 |
Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease S Nabhani, S Ginzel, H Miskin, S Revel-Vilk, D Harlev, B Fleckenstein, ... Haematologica 100 (9), 1189, 2015 | 24 | 2015 |
Recursive Dynamic Programming for Adaptive Sequence and Structure Alignment. R Thiele, R Zimmer, T Lengauer Ismb 3, 384-392, 1995 | 24 | 1995 |
A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma M Joosten, S Ginzel, C Blex, D Schmidt, M Gombert, C Chen, RM Linka, ... Molecular Oncology 10 (8), 1232-1244, 2016 | 21 | 2016 |
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Constitutional mismatch repair-deficiency and whole-exome sequencing as the means of the rapid detection of the causative MSH6 defect JI Hoell, M Gombert, S Ginzel, S Loth, P Landgraf, V Käfer, M Streiter, ... Klinische Pädiatrie 226 (06/07), 357-361, 2014 | 18 | 2014 |
Robust methods for EMC-driven routing D Theune, R Thiele, W John, T Lengauer IEEE Transactions on Computer-Aided Design of Integrated Circuits and …, 1994 | 16 | 1994 |
Graph-based sequence annotation using a data integration approach R Pesch, A Lysenko, M Hindle, K Hassani-Pak, R Thiele, C Rawlings, ... Journal of Integrative Bioinformatics 5 (2), 58-72, 2008 | 12 | 2008 |
Fast protein fold recognition and accurate sequence-structure alignment R Zimmer, R Thiele German Conference on Bioinformatics, 137-146, 1996 | 12 | 1996 |
The ToPLign Software Environment-Toolbox for Preotein Alignment H Mevissen, R Thiele, R Zimmer, T Lengauer Bioinformatik-Konferenz, Jena, 1994, 1994 | 8 | 1994 |
Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets JI Hoell, S Ginzel, M Kuhlen, A Kloetgen, M Gombert, U Fischer, D Hein, ... Blood advances 3 (20), 3143-3156, 2019 | 7 | 2019 |
Examining different analysis protocols targeting hospital sanitary facility microbiomes C Neidhöfer, E Sib, AH Benhsain, C Mutschnik-Raab, A Schwabe, ... Microorganisms 11 (1), 185, 2023 | 4 | 2023 |
Analysis of the cervical microbiome in women from the German national cervical cancer screening program M Condic, C Neidhöfer, DJ Ralser, N Wetzig, R Thiele, M Sieber, LA Otten, ... Journal of Cancer Research and Clinical Oncology 149 (9), 6489-6500, 2023 | 3 | 2023 |