Mandana Arbab

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David R. LiuHarvard UniversityVerified email at fas.harvard.edu
Max W ShenGenentechVerified email at mit.edu
Richard I SherwoodBrigham and Women's HospitalVerified email at partners.org
Christopher CassaAssistant Professor, Harvard Medical School; Lecturer, Massachusetts Institute of TechnologyVerified email at mit.edu
Gregory Arthur NewbyAssistant Professor, Johns Hopkins University Department of Genetic MedicineVerified email at jhmi.edu
Jonathan Y. HsuGraduate StudentVerified email at mit.edu
Żaneta MatuszekHarvard UniversityVerified email at fas.harvard.edu
Beverly MokResearch FellowVerified email at imcb.a-star.edu.sg
Tony P HuangHarvard UniversityVerified email at g.harvard.edu
Joseph ReplogleMD-PhD student, Weissman lab @ UCSF / Whitehead Institute / MITVerified email at wi.mit.edu
Jonathan S. WeissmanUCSF/HHMIVerified email at ucsf.edu
Britt AdamsonAssistant Professor, PrincetonVerified email at princeton.edu
Andrew AnzaloneBroad Institute of MIT and HarvardVerified email at broadinstitute.org
Shannon M MillerThe Scripps Research InstituteVerified email at scripps.edu
Holly ReesBeam TherapeuticsVerified email at beamtx.com
Jeffrey A. HussmannUCSF / WhiteheadVerified email at wi.mit.edu
Tatsunori HashimotoAssistant Professor, StanfordVerified email at stanford.edu
Lennart KesterPrincess Maxima Center for pediatric oncologyVerified email at prinsesmaximacentrum.nl
Albert J. R. HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center and Utrecht UniversityVerified email at uu.nl
Alexander van OudenaardenHubrecht InstituteVerified email at hubrecht.eu

Mandana Arbab

Assistant Professor at Boston Children's Hospital and Harvard Medical School

Verified email at childrens.harvard.edu - Homepage

genome editing molecular biology neurodegeneration


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Predictable and precise template-free CRISPR editing of pathogenic variants MW Shen, M Arbab, JY Hsu, D Worstell, SJ Culbertson, O Krabbe, ... Nature 563 (7733), 646-651, 2018	513	2018
Continuous evolution of SpCas9 variants compatible with non-G PAMs SM Miller, T Wang, PB Randolph, M Arbab, MW Shen, TP Huang, ... Nature Biotechnology 38 (4), 471-481, 2020	290	2020
Determinants of base editing outcomes from target library analysis and machine learning M Arbab, MW Shen, B Mok, C Wilson, Ż Matuszek, CA Cassa, DR Liu Cell 182 (2), 463-480. e30, 2020	209	2020
Efficient C• G-to-G• C base editors developed using CRISPRi screens, target-library analysis, and machine learning LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ... Nature biotechnology 39 (11), 1414-1425, 2021	152	2021
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity ME Neugebauer, A Hsu, M Arbab, NA Krasnow, AN McElroy, S Pandey, ... Nature biotechnology 41 (5), 673-685, 2023	71	2023
Cloning-free CRISPR M Arbab, S Srinivasan, T Hashimoto, N Geijsen, RI Sherwood Stem cell reports 5 (5), 908-917, 2015	66	2015
Base editing rescue of spinal muscular atrophy in cells and in mice M Arbab, Z Matuszek, KM Kray, A Du, GA Newby, AJ Blatnik, A Raguram, ... Science 380 (6642), eadg6518, 2023	52	2023
Modeling motor neuron disease: the matter of time M Arbab, S Baars, N Geijsen Trends in neurosciences 37 (11), 642-652, 2014	36	2014
DAZL regulates Tet1 translation in murine embryonic stem cells M Welling, HH Chen, J Muñoz, MU Musheev, L Kester, JP Junker, ... EMBO reports 16 (7), 791-802, 2015	28	2015
Systems and methods for predicting repair outcomes in genetic engineering MW SHEN, JYT HSU, M ARBAB, DK Gifford, DR Liu, RI SHERWOOD	10	2020
Self‐Cloning CRISPR M Arbab, RI Sherwood Current protocols in stem cell biology 38 (1), 5B. 5.1-5B. 5.16, 2016	7	2016
BASE EDITOR PREDICTIVE ALGORITHM AND METHOD OF USE DR Liu, M Arbab, MW Shen, C Cassa US Patent App. 17/797,697, 2023	5	2023
Gene editing methods for treating spinal muscular atrophy DR Liu, M ARBAB	5	2021
A multi-parametric flow cytometric assay to analyze DNA–protein interactions M Arbab, S Mahony, H Cho, JM Chick, PA Rolfe, JP Van Hoff, VWS Morris, ... Nucleic acids research 41 (2), e38-e38, 2013	5	2013
Author Correction: Efficient C• G-to-G• C base editors developed using CRISPRi screens, target-library analysis, and machine learning LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ... Nature Biotechnology, 1-1, 2023		2023
Predicting and Improving Insertions by Prime Editing M Arbab		2019
Methods and kits for cloning-free genome editing R Sherwood, M Arbab US Patent App. 15/569,232, 2019		2019
615 The Brain Prize 2014: complex human functions AS Thrane, VR Thrane, M Nedergaard, ER Zimmer, MJ Parent, AC Cuello, ...

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