Structure of the IFNγ receptor complex guides design of biased agonists JL Mendoza, NK Escalante, KM Jude, J Sotolongo Bellon, L Su, ... Nature 567 (7746), 56-60, 2019 | 116 | 2019 |
The IFN-λ-IFN-λR1-IL-10Rβ complex reveals structural features underlying type III IFN functional plasticity JL Mendoza, WM Schneider, HH Hoffmann, K Vercauteren, KM Jude, ... Immunity 46 (3), 379-392, 2017 | 103 | 2017 |
CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition Y Abdolazimi, Z Zhao, S Lee, H Xu, P Allegretti, TM Horton, B Yeh, ... Endocrinology 159 (9), 3143-3157, 2018 | 65 | 2018 |
Zinc-chelating small molecules preferentially accumulate and function within pancreatic β cells TM Horton, PA Allegretti, S Lee, HP Moeller, M Smith, JP Annes Cell chemical biology 26 (2), 213-222. e6, 2019 | 27 | 2019 |
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding PR Visperas, JA Winger, TM Horton, NH Shah, DJ Aum, A Tao, T Barros, ... Biochemical Journal 465 (1), 149-161, 2015 | 23 | 2015 |
Generation of highly potent DYRK1A-dependent inducers of human β-Cell replication via Multi-Dimensional compound optimization PA Allegretti, TM Horton, Y Abdolazimi, HP Moeller, B Yeh, M Caffet, ... Bioorganic & medicinal chemistry 28 (1), 115193, 2020 | 21 | 2020 |
PAM staining intensity of primary neuroendocrine neoplasms is a potential prognostic biomarker TM Horton, V Sundaram, CHJ Lee, K Hornbacker, A Van Vleck, ... Scientific Reports 10 (1), 10943, 2020 | 6 | 2020 |
Novel Pathogenic De Novo INS p.T97P Variant Presenting With Severe Neonatal DKA RA Lal, HP Moeller, EA Thomson, TM Horton, S Lee, R Freeman, ... Endocrinology 163 (2), bqab246, 2022 | 2 | 2022 |
Protocol for determining zinc-dependent β cell-selective small-molecule delivery in mouse pancreas TM Horton, BR Kraemer, JP Annes STAR protocols 2 (1), 100263, 2021 | 1 | 2021 |
Generation of Highly Potent DYRK1A-Dependent Inducers of Human β-Cell Replication via Multi-Dimensional Compound Optimization. PA Adapted from Allegretti, TM Horton, Y Abdolazimi, HP Moeller, B Yeh, ... CONFRONTING THE CENTRAL CHALLENGE OF BETA CELL REGENERATION: CELL LINEAGE …, 2020 | | 2020 |
Supplementary Data for: PAM Staining Intensity of Primary Neuroendocrine Neoplasms Is A Potential Prognostic Biomarker TM Horton, V Sundaram, CHJ Lee, K Hornbacker, A Van Vleck, ... CONFRONTING THE CENTRAL CHALLENGE OF BETA CELL REGENERATION: CELL LINEAGE …, 2020 | | 2020 |
Confronting the Central Challenge of Beta Cell Regeneration: Cell Lineage-Selective Activity TM Horton Stanford University, 2020 | | 2020 |
Structure of an engineered IFN-lambda/IFN-lambda R1/IL-10R beta complex provides insight into the functional dichotomy of type III versus type I IFNs JL Mendoza, WM Schneider, HH Hoffman, K Vercauteren, KM Jude, ... CYTOKINE 100, 46-46, 2017 | | 2017 |
Perspectives from peer instructors in a POGIL course T Horton, K Willis, MD Perry Jr ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | | 2014 |
Inhibiting recognition of the B-cell receptor by the tyrosine kinase Syk TM Horton, PR Visperas, J Kuriyan ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | | 2014 |
NOVEL APPROACH TO IDENTIFYING CYP2C9 RESIDUES RESPONSIBLE FOR STEREOSELECTIVE BINDING AND OXIDATION OF COMPOUNDS GP Miller, TM Horton, SC Cobb, MD Perry Jr DRUG METABOLISM REVIEWS 45, 235-236, 2014 | | 2014 |
Application of computational docking to examine metabolism of chiral drugs by CYP2C9 TM Horton, GP Miller, MD Perry Jr ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |