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Timothy M. Horton
Timothy M. Horton
University of Miami Miller School of Medicine
Verified email at med.miami.edu
Title
Cited by
Cited by
Year
Structure of the IFNγ receptor complex guides design of biased agonists
JL Mendoza, NK Escalante, KM Jude, J Sotolongo Bellon, L Su, ...
Nature 567 (7746), 56-60, 2019
1162019
The IFN-λ-IFN-λR1-IL-10Rβ complex reveals structural features underlying type III IFN functional plasticity
JL Mendoza, WM Schneider, HH Hoffmann, K Vercauteren, KM Jude, ...
Immunity 46 (3), 379-392, 2017
1032017
CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition
Y Abdolazimi, Z Zhao, S Lee, H Xu, P Allegretti, TM Horton, B Yeh, ...
Endocrinology 159 (9), 3143-3157, 2018
652018
Zinc-chelating small molecules preferentially accumulate and function within pancreatic β cells
TM Horton, PA Allegretti, S Lee, HP Moeller, M Smith, JP Annes
Cell chemical biology 26 (2), 213-222. e6, 2019
272019
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding
PR Visperas, JA Winger, TM Horton, NH Shah, DJ Aum, A Tao, T Barros, ...
Biochemical Journal 465 (1), 149-161, 2015
232015
Generation of highly potent DYRK1A-dependent inducers of human β-Cell replication via Multi-Dimensional compound optimization
PA Allegretti, TM Horton, Y Abdolazimi, HP Moeller, B Yeh, M Caffet, ...
Bioorganic & medicinal chemistry 28 (1), 115193, 2020
212020
PAM staining intensity of primary neuroendocrine neoplasms is a potential prognostic biomarker
TM Horton, V Sundaram, CHJ Lee, K Hornbacker, A Van Vleck, ...
Scientific Reports 10 (1), 10943, 2020
62020
Novel Pathogenic De Novo INS p.T97P Variant Presenting With Severe Neonatal DKA
RA Lal, HP Moeller, EA Thomson, TM Horton, S Lee, R Freeman, ...
Endocrinology 163 (2), bqab246, 2022
22022
Protocol for determining zinc-dependent β cell-selective small-molecule delivery in mouse pancreas
TM Horton, BR Kraemer, JP Annes
STAR protocols 2 (1), 100263, 2021
12021
Generation of Highly Potent DYRK1A-Dependent Inducers of Human β-Cell Replication via Multi-Dimensional Compound Optimization.
PA Adapted from Allegretti, TM Horton, Y Abdolazimi, HP Moeller, B Yeh, ...
CONFRONTING THE CENTRAL CHALLENGE OF BETA CELL REGENERATION: CELL LINEAGE …, 2020
2020
Supplementary Data for: PAM Staining Intensity of Primary Neuroendocrine Neoplasms Is A Potential Prognostic Biomarker
TM Horton, V Sundaram, CHJ Lee, K Hornbacker, A Van Vleck, ...
CONFRONTING THE CENTRAL CHALLENGE OF BETA CELL REGENERATION: CELL LINEAGE …, 2020
2020
Confronting the Central Challenge of Beta Cell Regeneration: Cell Lineage-Selective Activity
TM Horton
Stanford University, 2020
2020
Structure of an engineered IFN-lambda/IFN-lambda R1/IL-10R beta complex provides insight into the functional dichotomy of type III versus type I IFNs
JL Mendoza, WM Schneider, HH Hoffman, K Vercauteren, KM Jude, ...
CYTOKINE 100, 46-46, 2017
2017
Perspectives from peer instructors in a POGIL course
T Horton, K Willis, MD Perry Jr
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014
2014
Inhibiting recognition of the B-cell receptor by the tyrosine kinase Syk
TM Horton, PR Visperas, J Kuriyan
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014
2014
NOVEL APPROACH TO IDENTIFYING CYP2C9 RESIDUES RESPONSIBLE FOR STEREOSELECTIVE BINDING AND OXIDATION OF COMPOUNDS
GP Miller, TM Horton, SC Cobb, MD Perry Jr
DRUG METABOLISM REVIEWS 45, 235-236, 2014
2014
Application of computational docking to examine metabolism of chiral drugs by CYP2C9
TM Horton, GP Miller, MD Perry Jr
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013
2013
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Articles 1–17