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Sapphire Energy
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Year
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 9,988,624, 2018
2072018
Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae
SJ Szyjka, CJ Viggiani, OM Aparicio
Molecular cell 19 (5), 691-697, 2005
2072005
Pph3–Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage
BM O'Neill, SJ Szyjka, ET Lis, AO Bailey, JR Yates III, OM Aparicio, ...
Proceedings of the National Academy of Sciences 104 (22), 9290-9295, 2007
1762007
H2A. Z functions to regulate progression through the cell cycle
N Dhillon, M Oki, SJ Szyjka, OM Aparicio, RT Kamakaka
Molecular and cellular biology, 2006
1292006
Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae
SJ Szyjka, JG Aparicio, CJ Viggiani, S Knott, W Xu, S Tavaré, OM Aparicio
Genes & development 22 (14), 1906-1920, 2008
1092008
Evaluation of phenotype stability and ecological risk of a genetically engineered alga in open pond production
SJ Szyjka, S Mandal, NG Schoepp, BM Tyler, CB Yohn, YS Poon, ...
Algal Research 24, 378-386, 2017
742017
An exogenous chloroplast genome for complex sequence manipulation in algae
BM O'Neill, KL Mikkelson, NM Gutierrez, JL Cunningham, KL Wolff, ...
Nucleic acids research 40 (6), 2782-2792, 2012
692012
DNA polymerase ε, acetylases and remodellers cooperate to form a specialized chromatin structure at a tRNA insulator
N Dhillon, J Raab, J Guzzo, SJ Szyjka, S Gangadharan, OM Aparicio, ...
The EMBO Journal 28 (17), 2583-2600, 2009
562009
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 10,047,358, 2018
282018
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 10,336,998, 2019
272019
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 10,457,933, 2019
242019
Systematic investigation of CRISPR–Cas9 configurations for flexible and efficient genome editing in Corynebacterium glutamicum NRRL-B11474
R Cameron Coates, S Blaskowski, S Szyjka, HM van Rossum, ...
Journal of Industrial Microbiology and Biotechnology 46 (2), 187-201, 2019
142019
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 10,647,980, 2020
132020
Systems and methods for host cell improvement utilizing epistatic effects
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 11,085,040, 2021
122021
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 10,808,243, 2020
122020
Automated system for HTP genomic engineering
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 10,883,101, 2021
102021
Automated system for HTP genomic engineering
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 10,745,694, 2020
102020
HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 10,968,445, 2021
92021
Automated system for HTP genomic engineering
Z Serber, EJ Dean, S Manchester, K Gora, M Flashman, E Shellman, ...
US Patent 11,155,807, 2021
72021
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ DEAN, S Manchester, K Gora, M Flashman, E Shellman, ...
72017
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