| New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 919 | 2022 |
| A meta-analysis of genome-wide association studies identifies multiple longevity genes J Deelen, DS Evans, DE Arking, N Tesi, M Nygaard, X Liu, MK Wojczynski, ... Nature communications 10 (1), 3669, 2019 | 264 | 2019 |
| Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ... Nature communications 12 (1), 3417, 2021 | 190* | 2021 |
| A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the … SJ Van Der Lee, OJ Conway, I Jansen, MM Carrasquillo, L Kleineidam, ... Acta neuropathologica 138, 237-250, 2019 | 103 | 2019 |
| Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease H Holstege, M Hulsman, C Charbonnier, B Grenier-Boley, O Quenez, ... Nature genetics 54 (12), 1786-1794, 2022 | 88* | 2022 |
| Centenarian controls increase variant effect sizes by an average twofold in an extreme case–extreme control analysis of Alzheimer’s disease N Tesi, SJ van der Lee, M Hulsman, IE Jansen, N Stringa, N van Schoor, ... European Journal of Human Genetics 27 (2), 244-253, 2019 | 61 | 2019 |
| Longitudinal maintenance of cognitive health in centenarians in the 100-plus study N Beker, SAM Sikkes, M Hulsman, N Tesi, SJ van der Lee, P Scheltens, ... JAMA network open 3 (2), e200094-e200094, 2020 | 42 | 2020 |
| Immune response and endocytosis pathways are associated with the resilience against Alzheimer’s disease N Tesi, SJ Van Der Lee, M Hulsman, IE Jansen, N Stringa, ... Translational psychiatry 10 (1), 1-12, 2020 | 41 | 2020 |
| Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers IE Jansen, SJ van der Lee, D Gomez-Fonseca, I de Rojas, MC Dalmasso, ... Acta Neuropathologica 144 (5), 821-842, 2022 | 40 | 2022 |
| XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells D Moreno-Martínez, M Nomdedeu, MC Lara-Castillo, A Etxabe, ... Oncotarget 5 (12), 4337, 2014 | 27 | 2014 |
| Polygenic risk score of longevity predicts longer survival across an age continuum N Tesi, SJ van der Lee, M Hulsman, IE Jansen, N Stringa, NM van Schoor, ... The Journals of Gerontology: Series A 76 (5), 750-759, 2021 | 25 | 2021 |
| snpXplorer: a web application to explore human SNP-associations and annotate SNP-sets N Tesi, S van der Lee, M Hulsman, H Holstege, MJT Reinders Nucleic Acid Research 49 (W1), W603–W612, 2021 | 16 | 2021 |
| Risk of dementia in APOE ε4 carriers is mitigated by a polygenic risk score JL Ebenau, SJ van der Lee, M Hulsman, N Tesi, IE Jansen, IMW Verberk, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 13 (1 …, 2021 | 16 | 2021 |
| Emetine induces chemosensitivity and reduces clonogenicity of acute myeloid leukemia cells JM Cornet-Masana, D Moreno-Martínez, MC Lara-Castillo, M Nomdedeu, ... Oncotarget 7 (17), 23239, 2016 | 16 | 2016 |
| Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profiles BM Tijms, EM Vromen, O Mjaavatten, H Holstege, LM Reus, ... Nature aging, 1-15, 2024 | 14* | 2024 |
| Genetics contributes to concomitant pathology and clinical presentation in dementia with Lewy bodies SJ van der Lee, I van Steenoven, M van de Beek, N Tesi, IE Jansen, ... Journal of Alzheimer's Disease 83 (1), 269-279, 2021 | 13 | 2021 |
| Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological … LM Reus, IE Jansen, MO Mol, F van Ruissen, J van Rooij, NM van Schoor, ... Translational psychiatry 11 (1), 451, 2021 | 12 | 2021 |
| What does heritability of Alzheimer’s disease represent? E Baker, G Leonenko, KM Schmidt, M Hill, AJ Myers, M Shoai, I de Rojas, ... PloS one 18 (4), e0281440, 2023 | 10 | 2023 |
| The effect of Alzheimer’s disease-associated genetic variants on longevity N Tesi, M Hulsman, SJ van der Lee, IE Jansen, N Stringa, NM van Schoor, ... Frontiers in Genetics 12, 748781, 2021 | 8 | 2021 |
| C-terminal BRE overexpression in 11q23-rearranged and t (8; 16) acute myeloid leukemia is caused by intragenic transcription initiation AE Marneth, KHM Prange, ASA Al Hinai, SM Bergevoet, N Tesi, ... Leukemia 32 (3), 828-836, 2018 | 7 | 2018 |
