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Jose C Fernandez-Checa
Jose C Fernandez-Checa
CSIC
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13110*2021
Mitochondrial glutathione, a key survival antioxidant
M Marí, A Morales, A Colell, C García-Ruiz, JC Fernández-Checa
Antioxidants & redox signaling 11 (11), 2685-2700, 2009
10652009
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species: role of mitochondrial glutathione
C García-Ruiz, A Colell, M Marí, A Morales, JC Fernández-Checa
Journal of Biological Chemistry 272 (17), 11369-11377, 1997
9561997
Mitochondrial free cholesterol loading sensitizes to TNF-and Fas-mediated steatohepatitis
M Marí, F Caballero, A Colell, A Morales, J Caballeria, A Fernandez, ...
Cell metabolism 4 (3), 185-198, 2006
7312006
Glutathione and mitochondria
V Ribas, C García-Ruiz, JC Fernández-Checa
Frontiers in pharmacology 5, 102805, 2014
5672014
GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect
JC Fernandez-Checa, N Kaplowitz, C Garcia-Ruiz, A Colell, M Miranda, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 273 (1 …, 1997
4991997
Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of …
C García-Ruiz, A Colell, A Morales, N Kaplowitz, JC Fernández-Checa
Molecular pharmacology 48 (5), 825-834, 1995
4401995
Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor
A Colell, C García-Ruiz, M Miranda, E Ardite, M Marí, A Morales, ...
Gastroenterology 115 (6), 1541-1551, 1998
4021998
Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH
F Caballero, A Fernández, AM De Lacy, JC Fernández-Checa, ...
Journal of hepatology 50 (4), 789-796, 2009
3982009
Hepatic mitochondrial glutathione: transport and role in disease and toxicity
JC Fernandez-Checa, N Kaplowitz
Toxicology and applied pharmacology 204 (3), 263-273, 2005
3832005
Sphingolipids and cell death
A Morales, H Lee, FM Goñi, R Kolesnick, JC Fernandez-Checa
Apoptosis 12, 923-939, 2007
2992007
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione
F Caballero, A Fernández, N Matías, L Martínez, R Fucho, M Elena, ...
Journal of Biological Chemistry 285 (24), 18528-18536, 2010
2972010
Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice
C García-Ruiz, A Colell, M Marí, A Morales, M Calvo, C Enrich, ...
The Journal of clinical investigation 111 (2), 197-208, 2003
2902003
Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma
J Montero, A Morales, L Llacuna, JM Lluis, O Terrones, G Basanez, ...
Cancer research 68 (13), 5246-5256, 2008
2782008
Mitochondrial glutathione: importance and transport
JC Fernández-Checa, N Kaplowitz, C García-Ruiz, A Colell
Seminars in liver disease 18 (04), 389-401, 1998
2661998
Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress.
JC Fernandez-Checa, C Garcia-Ruiz, M Ookhtens, N Kaplowitz
The Journal of clinical investigation 87 (2), 397-405, 1991
2581991
VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis
M Sans, J Panés, E Ardite, JI Elizalde, Y Arce, M Elena, A Palacín, ...
Gastroenterology 116 (4), 874-883, 1999
2551999
Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats
A Hirano, N Kaplowitz, H Tsukamoto, S Kamimura, JC Fernandez-Checa
Hepatology 16 (6), 1423-1427, 1992
2541992
Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-κB via c-SRC–and oxidant-dependent cell death
JM Lluis, F Buricchi, P Chiarugi, A Morales, JC Fernandez-Checa
Cancer research 67 (15), 7368-7377, 2007
2492007
Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes.
C Garcia-Ruiz, A Morales, A Ballesta, J Rodes, N Kaplowitz, ...
The Journal of clinical investigation 94 (1), 193-201, 1994
2431994
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