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Adam Kreutzer
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Elucidating the structures of amyloid oligomers with macrocyclic β-hairpin peptides: Insights into Alzheimer’s disease and other amyloid diseases
AG Kreutzer, JS Nowick
Accounts of chemical research 51 (3), 706-718, 2018
1002018
X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an Aβ17–36 β-Hairpin
AG Kreutzer, IL Hamza, RK Spencer, JS Nowick
Journal of the American Chemical Society 138 (13), 4634-4642, 2016
832016
Stabilization, assembly, and toxicity of trimers derived from Aβ
AG Kreutzer, S Yoo, RK Spencer, JS Nowick
Journal of the American Chemical Society 139 (2), 966-975, 2017
682017
A cyclic peptide inhibitor of the SARS-CoV-2 main protease
AG Kreutzer, M Krumberger, EM Diessner, CMT Parrocha, MA Morris, ...
European journal of medicinal chemistry 221, 113530, 2021
342021
Structure-based drug design of an inhibitor of the SARS-CoV-2 (COVID-19) main protease using free software: A tutorial for students and scientists
S Zhang, M Krumberger, MA Morris, CMT Parrocha, AG Kreutzer, ...
European journal of medicinal chemistry 218, 113390, 2021
332021
X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from Aβ16–36
PJ Salveson, RK Spencer, AG Kreutzer, JS Nowick
Organic letters 19 (13), 3462-3465, 2017
302017
X-ray Crystallographic Structures of Oligomers of Peptides Derived from β2-Microglobulin
RK Spencer, AG Kreutzer, PJ Salveson, H Li, JS Nowick
Journal of the American Chemical Society 137 (19), 6304-6311, 2015
302015
Repurposing triphenylmethane dyes to bind to trimers derived from Aβ
PJ Salveson, S Haerianardakani, A Thuy-Boun, S Yoo, AG Kreutzer, ...
Journal of the American Chemical Society 140 (37), 11745-11754, 2018
282018
Exploring amyloid oligomers with peptide model systems
TD Samdin, AG Kreutzer, JS Nowick
Current opinion in chemical biology 64, 106-115, 2021
272021
A Hexamer of a Peptide Derived from Aβ16–36
AG Kreutzer, RK Spencer, KJ McKnelly, S Yoo, IL Hamza, PJ Salveson, ...
Biochemistry 56 (45), 6061-6071, 2017
262017
Controlling the oligomerization state of Aβ-derived peptides with light
PJ Salveson, S Haerianardakani, A Thuy-Boun, AG Kreutzer, JS Nowick
Journal of the American Chemical Society 140 (17), 5842-5852, 2018
252018
An efficient method for the expression and purification of Aβ (M1–42)
S Yoo, S Zhang, AG Kreutzer, JS Nowick
Biochemistry 57 (26), 3861-3866, 2018
212018
Peptidic inhibitors of insulin-degrading enzyme with potential for dermatological applications discovered via phage display
CN Suire, S Nainar, M Fazio, AG Kreutzer, T Paymozd-Yazdi, CL Topper, ...
PLoS One 13 (2), e0193101, 2018
202018
X-ray Crystallography Reveals Parallel and Antiparallel β-Sheet Dimers of a β-Hairpin Derived from Aβ16–36 that Assemble to Form Different Tetramers
AG Kreutzer, TD Samdin, G Guaglianone, RK Spencer, JS Nowick
ACS chemical neuroscience 11 (15), 2340-2347, 2020
192020
Effects of N-terminal residues on the assembly of constrained β-hairpin peptides derived from Aβ
TD Samdin, M Wierzbicki, AG Kreutzer, WJ Howitz, M Valenzuela, A Smith, ...
Journal of the American Chemical Society 142 (26), 11593-11601, 2020
132020
A tetramer derived from islet amyloid polypeptide
Y Wang, AG Kreutzer, NL Truex, JS Nowick
The Journal of organic chemistry 82 (15), 7905-7912, 2017
132017
Square channels formed by a peptide derived from transthyretin
S Yoo, AG Kreutzer, NL Truex, JS Nowick
Chemical Science 7 (12), 6946-6951, 2016
102016
Phenylalanine mutation to cyclohexylalanine facilitates triangular trimer formation by β-hairpins derived from Aβ
S Haerianardakani, AG Kreutzer, PJ Salveson, TD Samdin, ...
Journal of the American Chemical Society 142 (49), 20708-20716, 2020
92020
Effects of Familial Alzheimer’s Disease Mutations on the Assembly of a β-Hairpin Peptide Derived from Aβ16–36
KJ McKnelly, AG Kreutzer, WJ Howitz, K Haduong, S Yoo, C Hart, ...
Biochemistry 61 (6), 446-454, 2022
82022
A disulfide-stabilized Aβ that forms dimers but does not form fibrils
S Zhang, S Yoo, DT Snyder, BB Katz, A Henrickson, B Demeler, ...
Biochemistry 61 (4), 252-264, 2022
62022
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