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Year
Drug delivery systems for elemene, its main active ingredient β-elemene, and its derivatives in cancer therapy
B Zhai, Y Zeng, Z Zeng, N Zhang, C Li, Y Zeng, Y You, S Wang, X Chen, ...
International journal of nanomedicine, 6279-6296, 2018
1252018
Selective Tyk2 inhibitors as potential therapeutic agents: a patent review (2015–2018)
X He, X Chen, H Zhang, T Xie, XY Ye
Expert Opinion on Therapeutic Patents 29 (2), 137-149, 2019
652019
Long-acting cocaine hydrolase for addiction therapy
X Chen, L Xue, S Hou, Z Jin, T Zhang, F Zheng, CG Zhan
Proceedings of the National Academy of Sciences 113 (2), 422-427, 2016
632016
Cyclooxygenase-2 Genetic Variants Are Associated with Survival in Unresectable Locally Advanced Non–Small Cell Lung Cancer
N Bi, M Yang, L Zhang, X Chen, W Ji, G Ou, D Lin, L Wang
Clinical cancer research 16 (8), 2383-2390, 2010
512010
Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine
L Xue, S Hou, M Tong, L Fang, X Chen, Z Jin, HH Tai, F Zheng, CG Zhan
Biochemical Journal 453 (3), 447-454, 2013
452013
Role of histone post-translational modifications in inflammatory diseases
Y Lin, T Qiu, G Wei, Y Que, W Wang, Y Kong, T Xie, X Chen
Frontiers in Immunology 13, 852272, 2022
432022
Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification
L Fang, KM Chow, S Hou, L Xue, X Chen, DW Rodgers, F Zheng, ...
ACS chemical biology 9 (8), 1764-1772, 2014
422014
A quantitative LC–MS/MS method for simultaneous determination of cocaine and its metabolites in whole blood
X Chen, X Zheng, K Ding, Z Zhou, CG Zhan, F Zheng
Journal of pharmaceutical and biomedical analysis 134, 243-251, 2017
412017
Gene transfer of mutant mouse cholinesterase provides high lifetime expression and reduced cocaine responses with no evident toxicity
L Geng, Y Gao, X Chen, S Hou, CG Zhan, Z Radic, RJ Parks, SJ Russell, ...
PLoS One 8 (6), e67446, 2013
412013
Mccrearamycins A–D, Geldanamycin‐Derived Cyclopentenone Macrolactams from an Eastern Kentucky Abandoned Coal Mine Microbe
X Wang, Y Zhang, LV Ponomareva, Q Qiu, R Woodcock, SI Elshahawi, ...
Angewandte Chemie 129 (11), 3040-3044, 2017
362017
Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2
X Wang, SI Elshahawi, W Cai, Y Zhang, LV Ponomareva, X Chen, ...
Journal of natural products 80 (4), 1141-1149, 2017
322017
Clinical potential of an enzyme-based novel therapy for cocaine overdose
T Zhang, X Zheng, Z Zhou, X Chen, Z Jin, J Deng, CG Zhan, F Zheng
Scientific Reports 7 (1), 15303, 2017
292017
Metabolic enzymes of cocaine metabolite benzoylecgonine
X Chen, X Zheng, M Zhan, Z Zhou, CG Zhan, F Zheng
ACS chemical biology 11 (8), 2186-2194, 2016
262016
Genetic polymorphisms in STK15 and MMP-2 associated susceptibility to esophageal cancer in Mongolian population
XB Chen, GL Chen, JN Liu, JZ Yang, DK Yu, DX Lin, W Tan
Zhonghua yu Fang yi xue za zhi [Chinese Journal of Preventive Medicine] 43 …, 2009
252009
Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase
X Chen, X Huang, L Geng, L Xue, S Hou, X Zheng, S Brimijoin, F Zheng, ...
Biochemical Journal 466 (2), 243-251, 2015
242015
Effectiveness of a cocaine hydrolase for cocaine toxicity treatment in male and female rats
X Zheng, Z Zhou, T Zhang, Z Jin, X Chen, J Deng, CG Zhan, F Zheng
The AAPS journal 20, 1-7, 2018
232018
Chartspiroton, a Tetracyclic Spiro-naphthoquinone Derivative from a Medicinal Plant Endophytic Streptomyces
H Zhao, A Yang, J Liu, S Bao, R Peng, Y Hu, T Yuan, S Hou, T Xie, ...
Organic Letters 22 (10), 3739-3743, 2020
212020
Catalytic reaction mechanism for drug metabolism in human carboxylesterase-1: Cocaine hydrolysis pathway
J Yao, X Chen, F Zheng, CG Zhan
Molecular pharmaceutics 15 (9), 3871-3880, 2018
212018
Development of a long-acting Fc-fused cocaine hydrolase with improved yield of protein expression
X Chen, J Deng, X Zheng, J Zhang, Z Zhou, H Wei, CG Zhan, F Zheng
Chemico-biological interactions 306, 89-95, 2019
202019
New peptidendrocins and anticancer chartreusin from an endophytic bacterium of Dendrobium officinale
H Zhao, X Chen, X Chen, Y Zhu, Y Kong, S Zhang, X Deng, P Ouyang, ...
Annals of translational medicine 8 (7), 2020
192020
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