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Thirukumaran Kandasamy
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Multi‐targeted drug repurposing approach for breast cancer via integrated functional network analysis
T Kandasamy, P Sen, SS Ghosh
Molecular informatics 41 (8), 2100300, 2022
112022
Rational design of Shewanella sp. L-arabinose isomerase for D-galactose isomerase activity under mesophilic conditions
AB Jayaraman, T Kandasamy, D Venkataraman, S Meenakshisundaram
Enzyme and Microbial Technology 147, 109796, 2021
112021
Insights into the molecular mechanisms of histone code recognition by the BRPF3 bromodomain
S Barman, A Roy, I Bardhan, T Kandasamy, S Shivani, B Sudhamalla
Chemistry–An Asian Journal 16 (21), 3404-3412, 2021
102021
Multi-targeting TACE/ADAM17 and gamma-secretase of notch signalling pathway in TNBC via drug repurposing approach using Lomitapide
P Sen, T Kandasamy, SS Ghosh
Cellular Signalling 102, 110529, 2023
92023
In silico approach to target PI3K/Akt/mTOR axis by selected Olea europaea phenols in PIK3CA mutant colorectal cancer
A Sain, T Kandasamy, D Naskar
Journal of Biomolecular Structure and Dynamics 40 (21), 10962-10977, 2022
72022
Designing of RNA aptamer against DNA binding domain of the glucocorticoid receptor: A response element-based in-silico approach
T Kandasamy, B Sudhamalla, D Naskar
Journal of Biomolecular Structure and Dynamics 40 (3), 1120-1127, 2022
52022
Report on biopharmaceutical profile of recent biotherapeutics and insilco docking studies on target bindings of known aptamer biotherapeutics
S Manibalan, K Thirukumaran, M Varshni, A Shobana, A Achary
Biotechnology and Genetic Engineering Reviews 36 (2), 57-80, 2020
52020
Protein network studies on PCOS biomarkers with S100A8, druggability assessment, and RNA aptamer designing to control its cyst migration effect
S Manibalan, A Shobana, M Kiruthika, A Achary, M Swathi, ...
Frontiers in bioengineering and biotechnology 8, 328, 2020
52020
In-silico evidence of ADAM metalloproteinase pathology in cancer signaling networks
P Sen, T Kandasamy, SS Ghosh
Journal of Biomolecular Structure and Dynamics 40 (22), 11771-11786, 2022
42022
Targeting UNC-51-like kinase 1 and 2 by lignans to modulate autophagy: Possible implications in metastatic colorectal cancer
A Sain, T Kandasamy, D Naskar
Molecular Diversity 27 (1), 27-43, 2023
32023
In silico approach for enhancing innate lipid content of Yarrowia lipolytica, by blocking the acyl-CoA oxidase-1 enzyme, using various analogous compounds of lipids
MA Sundaramahalingam, C Amrutha, J Rajeshbanu, K Thirukumaran, ...
Journal of Biomolecular Structure and Dynamics 41 (2), 511-524, 2023
22023
Dual therapeutic approach to modulate Glycogen Synthase kinase− 3 beta (GSK-3Β) and inhibitor of nuclear factor kappa kinase-beta (IKK-β) receptors by in silico designing of …
SR Acharyya, P Sen, T Kandasamy, SS Ghosh
Journal of Molecular Graphics and Modelling 115, 108225, 2022
22022
Targeting Protein Tyrosine Phosphatase 1B in Obesity‐associated Colon Cancer: Possible Role of Sweet Potato (Ipomoea batatas)
A Sain, D Khamrai, T Kandasamy, D Naskar
Proteins: Structure, Function, and Bioinformatics, 2022
12022
Targeting AR-positive breast cancer cells via drug repurposing approach
P Dutta, P Sen, T Kandasamy, SS Ghosh
Computational Biology and Chemistry 108, 108007, 2024
2024
In vitro anticancer effects of recombinant anisoplin through activation of SAPK/JNK and downregulation of NFκB
A Patra, T Kandasamy, SS Ghosh, GK Saini
Toxicology in Vitro 94, 105737, 2024
2024
Amyloid Targeting Red Emitting AIE Dots for Diagnostic and Therapeutic Application against Alzheimer’s Disease
P Ghosh, K Shokeen, S Mondal, T Kandasamy, S Kumar, SS Ghosh, ...
ACS Chemical Neuroscience 15 (2), 268-277, 2024
2024
Apigenin exerts anti-cancer effects in colon cancer by targeting HSP90AA1
A Sain, D Khamrai, T Kandasamy, D Naskar
Journal of Biomolecular Structure and Dynamics, 1-13, 2023
2023
Synthesis of 3-sulfenylindole derivatives from 4-hydroxy-2H-chromene-2-thione and indole using oxidative cross-dehydrogenative coupling reaction and anti-proliferative activity …
A Xalxo, UJ Goswami, S Sarkar, T Kandasamy, K Mehta, SS Ghosh, ...
Bioorganic Chemistry 141, 106900, 2023
2023
In silico screening and identification of potential drug against p300 acetyltransferase activity in breast cancer via drug repurposing approach
S Sarkar, T Kandasamy, R Shome, SS Ghosh
Journal of Biomolecular Structure and Dynamics, 1-12, 2023
2023
Designing of disruptor molecules to restrain the protein–protein interaction network of VANG1/SCRIB/NOS1AP using fragment-based drug discovery techniques
SR Acharyya, P Sen, T Kandasamy, SS Ghosh
Molecular Diversity 27 (3), 989-1010, 2023
2023
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