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Viswanath Das
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Nucleosidic DNA demethylating epigenetic drugs–a comprehensive review from discovery to clinic
K Agrawal, V Das, P Vyas, M Hajdúch
Pharmacology & therapeutics 188, 45-79, 2018
1252018
Pathophysiologically relevant in vitro tumor models for drug screening
V Das, F Bruzzese, P Konečný, F Iannelli, A Budillon, M Hajduch
Drug discovery today 20 (7), 848-855, 2015
662015
Metallacarborane sulfamides: Unconventional, specific, and highly selective inhibitors of carbonic anhydrase IX
B Grüner, J Brynda, V Das, V Šícha, J Štěpánková, J Nekvinda, ...
Journal of Medicinal Chemistry 62 (21), 9560-9575, 2019
552019
Microtubule stabilization by peloruside A and paclitaxel rescues degenerating neurons from okadaic acid‐induced tau phosphorylation
V Das, JH Miller
European Journal of Neuroscience 35 (11), 1705-1717, 2012
522012
Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer’s disease
N Annadurai, K Agrawal, P Džubák, M Hajdúch, V Das
Cellular and molecular life sciences 74, 4159-4169, 2017
442017
Reproducibility of uniform spheroid formation in 384-well plates: The effect of medium evaporation
V Das, T Fürst, S Gurská, P Džubák, M Hajdúch
Journal of biomolecular screening 21 (9), 923-930, 2016
382016
Role of tumor hypoxia in acquisition of resistance to microtubule-stabilizing drugs
V Das, J Štěpánková, M Hajdúch, JH Miller
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1855 (2), 172-182, 2015
302015
Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX
J Dvořanová, M Kugler, J Holub, V Šícha, V Das, J Nekvinda, S El Anwar, ...
European Journal of Medicinal Chemistry 200, 112460, 2020
292020
Tau secretion and propagation: Perspectives for potential preventive interventions in Alzheimer's disease and other tauopathies
N Annadurai, JB De Sanctis, M Hajdúch, V Das
Experimental neurology 343, 113756, 2021
242021
Effect of taxoid and nontaxoid site microtubule‐stabilizing agents on axonal transport of mitochondria in untransfected and ECFP‐htau40‐transfected rat cortical neurons in culture
V Das, DA Sim, JH Miller
Journal of Neuroscience Research 92 (9), 1155-1166, 2014
232014
Inhibitors of CA IX enzyme based on polyhedral boron compounds
M Kugler, J Nekvinda, J Holub, S El Anwar, V Das, V Šícha, K Pospíšilová, ...
ChemBioChem 22 (18), 2741-2761, 2021
222021
Potential role of tubulin tyrosine ligase-like enzymes in tumorigenesis and cancer cell resistance
V Das, A Kanakkanthara, A Chan, JH Miller
Cancer letters 350 (1-2), 1-4, 2014
182014
Non-taxoid site microtubule-stabilizing drugs work independently of tau overexpression in mouse N2a neuroblastoma cells
V Das, JH Miller
Brain research 1489, 121-132, 2012
162012
Antitumour drugs targeting tau R3 VQIVYK and Cys322 prevent seeding of endogenous tau aggregates by exogenous seeds
N Annadurai, L Malina, M Salmona, L Diomede, A Bastone, A Cagnotto, ...
The FEBS Journal 289 (7), 1929-1949, 2022
142022
Potential for treatment of neurodegenerative diseases with natural products or synthetic compounds that stabilize microtubules
JH Miller, V Das
Current Pharmaceutical Design 26 (35), 4362-4372, 2020
142020
Triterpenoid pyrazines and pyridines–Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs
J Hodoň, I Frydrych, Z Trhlíková, J Pokorný, L Borková, S Benická, M Vlk, ...
European Journal of Medicinal Chemistry 243, 114777, 2022
132022
Tau R2 and R3 are essential regions for tau aggregation, seeding and propagation
N Annadurai, L Malina, J Malohlava, M Hajdúch, V Das
Biochimie 200, 79-86, 2022
122022
Evaporation-reducing culture condition increases the reproducibility of multicellular spheroid formation in microtiter plates
V Das, T Fürst, S Gurská, P Džubák, M Hajdúch
JoVE (Journal of Visualized Experiments), e55403, 2017
102017
Cell‐based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models
K Agrawal, V Das, M Otmar, M Krečmerová, P Džubák, M Hajdúch
Cytometry Part A 91 (2), 133-143, 2017
102017
Differential regulation of methylation-regulating enzymes by senescent stromal cells drives colorectal cancer cell response to DNA-demethylating Epi-drugs
K Agrawal, V Das, N Táborská, J Gurský, P Džubák, M Hajdúch
Stem Cells International 2018, 2018
82018
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Articles 1–20