Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin‐3 SV Todi, BJ Winborn, KM Scaglione, JR Blount, SM Travis, HL Paulson The EMBO journal 28 (4), 372-382, 2009 | 221 | 2009 |
Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117 SV Todi, KM Scaglione, JR Blount, V Basrur, KP Conlon, A Pastore, ... Journal of Biological Chemistry 285 (50), 39303-39313, 2010 | 114 | 2010 |
Systematic analysis of the physiological importance of deubiquitinating enzymes WL Tsou, MJ Sheedlo, ME Morrow, JR Blount, KM McGregor, C Das, ... Public Library of Science 7 (8), e43112, 2012 | 75 | 2012 |
Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23 JR Blount, WL Tsou, G Ristic, AA Burr, M Ouyang, H Galante, ... Nature communications 5 (1), 4638, 2014 | 70 | 2014 |
Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation JR Blount, AA Burr, A Denuc, G Marfany, SV Todi PloS one 7 (5), e36542, 2012 | 70 | 2012 |
Ubiquitination regulates the neuroprotective function of the deubiquitinase ataxin-3 in vivo WL Tsou, AA Burr, M Ouyang, JR Blount, KM Scaglione, SV Todi Journal of Biological Chemistry 288 (48), 34460-34469, 2013 | 61 | 2013 |
The deubiquitinase ataxin-3 requires Rad23 and DnaJ-1 for its neuroprotective role in Drosophila melanogaster WL Tsou, M Ouyang, RR Hosking, JR Sutton, JR Blount, AA Burr, SV Todi Neurobiology of disease 82, 12-21, 2015 | 53 | 2015 |
Interaction of the polyglutamine protein ataxin-3 with Rad23 regulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3 JR Sutton, JR Blount, K Libohova, WL Tsou, GS Joshi, HL Paulson, ... Human molecular genetics 26 (8), 1419-1431, 2017 | 43 | 2017 |
Differential toxicity of ataxin-3 isoforms in Drosophila models of Spinocerebellar Ataxia Type 3 SL Johnson, JR Blount, K Libohova, B Ranxhi, HL Paulson, WL Tsou, ... Neurobiology of disease 132, 104535, 2019 | 22 | 2019 |
Unanchored ubiquitin chains, revisited JR Blount, SL Johnson, SV Todi Frontiers in Cell and Developmental Biology 8, 582361, 2020 | 21 | 2020 |
Expression and Regulation of Deubiquitinase-Resistant, Unanchored Ubiquitin Chains in Drosophila JR Blount, K Libohova, GB Marsh, JR Sutton, SV Todi Scientific Reports 8 (1), 8513, 2018 | 15 | 2018 |
Targeting the VCP-binding motif of ataxin-3 improves phenotypes in Drosophila models of Spinocerebellar Ataxia Type 3 SL Johnson, K Libohova, JR Blount, AL Sujkowski, MV Prifti, WL Tsou, ... Neurobiology of disease 160, 105516, 2021 | 10 | 2021 |
Unanchored ubiquitin chains do not lead to marked alterations in gene expression in Drosophila melanogaster JR Blount, DN Meyer, C Akemann, SL Johnson, K Gurdziel, TR Baker, ... Biology open 8 (5), bio043372, 2019 | 10 | 2019 |
Evaluating Phenotypic and Transcriptomic Responses Induced by Low-Level VOCs in Zebrafish: Benzene as an Example CC Wu, JR Blount, A Haimbaugh, S Heldman, JN Shields, TR Baker Toxics 10 (7), 351, 2022 | 8 | 2022 |
Drosophila as a Model of Unconventional Translation in Spinocerebellar Ataxia Type 3 SL Johnson, MV Prifti, A Sujkowski, K Libohova, JR Blount, L Hong, ... Cells 11 (7), 1223, 2022 | 6 | 2022 |
Degron capability of the hydrophobic C‐terminus of the polyglutamine disease protein, ataxin‐3 JR Blount, SL Johnson, K Libohova, SV Todi, WL Tsou Journal of neuroscience research 98 (10), 2096-2108, 2020 | 5 | 2020 |
Isoleucine 44 hydrophobic patch controls toxicity of unanchored, linear ubiquitin chains through NF-κB signaling JR Blount, K Libohova, GM Silva, SV Todi Cells 9 (6), 1519, 2020 | 5 | 2020 |
Phenotypic and transcriptomic effects of developmental exposure to nanomolar levels of pesticides in zebrafish JR Blount, JN Shields, CC Wu, C Akemann, BB Baker, Z Siddiqua, ... Environmental Advances 7, 100151, 2022 | 3 | 2022 |
Lysine 117 on ataxin-3 modulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3 JR Blount, NC Patel, K Libohova, AL Harris, WL Tsou, A Sujkowski, ... Journal of the Neurological Sciences 454, 120828, 2023 | 1 | 2023 |
Adult-Onset Transcriptomic Effects of Developmental Exposure to Benzene in Zebrafish (Danio rerio): Evaluating a Volatile Organic Compound of Concern ML Connell, CC Wu, JR Blount, A Haimbaugh, EK Kintzele, D Banerjee, ... International journal of molecular sciences 24 (22), 16212, 2023 | 1 | 2023 |