Highly enantioselective ring opening of epoxides catalyzed by (salen) Cr (III) complexes LE Martinez, JL Leighton, DH Carsten, EN Jacobsen Journal of the American Chemical Society 117 (21), 5897-5898, 1995 | 750 | 1995 |
On the Mechanism of Asymmetric Nucleophilic Ring-Opening of Epoxides Catalyzed by (Salen)CrIII Complexes KB Hansen, JL Leighton, EN Jacobsen Journal of the American Chemical Society 118 (44), 10924-10925, 1996 | 452 | 1996 |
Total synthesis of (+)-calyculin A DA Evans, JR Gage, JL Leighton Journal of the American Chemical Society 114 (24), 9434-9453, 1992 | 386 | 1992 |
Strained silacycles in organic synthesis: A new reagent for the enantioselective allylation of aldehydes JWA Kinnaird, PY Ng, K Kubota, X Wang, JL Leighton Journal of the American Chemical Society 124 (27), 7920-7921, 2002 | 230 | 2002 |
Total synthesis of leucascandrolide A KR Hornberger, CL Hamblett, JL Leighton Journal of the American Chemical Society 122 (51), 12894-12895, 2000 | 228 | 2000 |
A highly practical and enantioselective reagent for the allylation of aldehydes K Kubota, JL Leighton Angewandte Chemie 115 (8), 976-978, 2003 | 212 | 2003 |
Enantioselective allylation of ketone-derived benzoylhydrazones: practical synthesis of tertiary carbinamines R Berger, K Duff, JL Leighton Journal of the American Chemical Society 126 (18), 5686-5687, 2004 | 172 | 2004 |
Orally active, nonpeptide oxytocin antagonists BE Evans, JL Leighton, KE Rittle, KF Gilbert, GF Lundell, NP Gould, ... Journal of medicinal chemistry 35 (21), 3919-3927, 1992 | 166 | 1992 |
Efficient synthesis of (R)-4-((trimethylsilyl) oxy)-2-cyclopentenone by enantioselective catalytic epoxide ring opening JL Leighton, EN Jacobsen The Journal of Organic Chemistry 61 (1), 389-390, 1996 | 161 | 1996 |
Catalytic asymmetric silane alcoholysis: practical access to chiral silanes DR Schmidt, SJ O'Malle, JL Leighton Journal of the American Chemical Society 125 (5), 1190-1191, 2003 | 160 | 2003 |
Toward a versatile allylation reagent: Practical, enantioselective allylation of acylhydrazones using strained silacycles R Berger, PMA Rabbat, JL Leighton Journal of the American Chemical Society 125 (32), 9596-9597, 2003 | 152 | 2003 |
Highly diastereo-and enantioselective reagents for aldehyde crotylation BM Hackman, PJ Lombardi, JL Leighton Organic Letters 6 (23), 4375-4377, 2004 | 132 | 2004 |
Asymmetric synthesis of calyculin A. 2. The C26-C37. gamma.-amino acid fragments DA Evans, JR Gage, JL Leighton, AS Kim The Journal of Organic Chemistry 57 (7), 1961-1963, 1992 | 129 | 1992 |
Asymmetric Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C DA Evans, JC Barrow, JL Leighton, AJ Robichaud, M Sefkow Journal of the American Chemical Society 116 (26), 12111-12112, 1994 | 128 | 1994 |
A more comprehensive and highly practical solution to enantioselective aldehyde crotylation H Kim, S Ho, JL Leighton Journal of the American Chemical Society 133 (17), 6517-6520, 2011 | 125 | 2011 |
A Simple and General Chiral Silicon Lewis Acid for Asymmetric Synthesis: Highly Enantioselective [3+ 2] Acylhydrazone− Enol Ether Cycloadditions S Shirakawa, PJ Lombardi, JL Leighton Journal of the American Chemical Society 127 (28), 9974-9975, 2005 | 122 | 2005 |
Silane and germane molecular electronics TA Su, H Li, RS Klausen, NT Kim, M Neupane, JL Leighton, ... Accounts of Chemical Research 50 (4), 1088-1095, 2017 | 110 | 2017 |
Enantioselective Friedel− Crafts Alkylations with Benzoylhydrazones Promoted by a Simple Strained Silacycle Reagent S Shirakawa, R Berger, JL Leighton Journal of the American Chemical Society 127 (9), 2858-2859, 2005 | 101 | 2005 |
Total synthesis of dolabelide D PK Park, SJ O'Malley, DR Schmidt, JL Leighton Journal of the American Chemical Society 128 (9), 2796-2797, 2006 | 91 | 2006 |
Highly Enantioselective Pictet–Spengler Reactions with α‐Ketoamide‐Derived Ketimines: Access to an Unusual Class of Quaternary α‐Amino Amides FR Bou‐Hamdan, JL Leighton Angewandte Chemie International Edition 48 (13), 2403-2406, 2009 | 89 | 2009 |