| Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature review G Chappell, IP Pogribny, KZ Guyton, I Rusyn Mutation Research/Reviews in Mutation Research 768, 27-45, 2016 | 168 | 2016 |
| A chemical–biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives FA Grimm, Y Iwata, O Sirenko, GA Chappell, FA Wright, DM Reif, ... Green chemistry 18 (16), 4407-4419, 2016 | 86 | 2016 |
| Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis JE Rager, M Suh, GA Chappell, CM Thompson, DM Proctor Toxicology letters 305, 40-50, 2019 | 74 | 2019 |
| Inbreeding Depression and Inbreeding Avoidance in a Natural Population of Guppies (Poecilia reticulata) AM Johnson, G Chappell, AC Price, F Helen Rodd, R Olendorf, ... Ethology 116 (5), 448-457, 2010 | 50 | 2010 |
| Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort JE Rager, SS Auerbach, GA Chappell, E Martin, CM Thompson, RC Fry Chemical research in toxicology 30 (10), 1911-1920, 2017 | 49 | 2017 |
| Assessment of the mode of action underlying the effects of GenX in mouse liver and implications for assessing human health risks GA Chappell, CM Thompson, JC Wolf, JM Cullen, JE Klaunig, LC Haws Toxicologic pathology 48 (3), 494-508, 2020 | 46 | 2020 |
| Genetic and epigenetic changes in fibrosis‐associated hepatocarcinogenesis in mice G Chappell, K Kutanzi, T Uehara, V Tryndyak, HH Hong, M Hoenerhoff, ... International Journal of Cancer 134 (12), 2778-2788, 2014 | 45 | 2014 |
| In vitro screening for population variability in toxicity of pesticide-containing mixtures N Abdo, BA Wetmore, GA Chappell, D Shea, FA Wright, I Rusyn Environment international 85, 147-155, 2015 | 41 | 2015 |
| Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation GR Keele, BC Quach, JW Israel, GA Chappell, L Lewis, A Safi, JM Simon, ... PLoS genetics 16 (1), e1008537, 2020 | 36 | 2020 |
| A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates M Suh, D Proctor, G Chappell, J Rager, C Thompson, S Borghoff, L Finch, ... Toxicology 402, 50-67, 2018 | 35 | 2018 |
| Epigenetic events determine tissue-specific toxicity of inhalational exposure to the genotoxic chemical 1, 3-butadiene in male C57BL/6J mice G Chappell, T Kobets, B O’Brien, N Tretyakova, D Sangaraju, O Kosyk, ... Toxicological Sciences 142 (2), 375-384, 2014 | 33 | 2014 |
| Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential H Jaeschke, FJ Murray, AD Monnot, D Jacobson-Kram, SM Cohen, ... Regulatory Toxicology and Pharmacology 120, 104859, 2021 | 27 | 2021 |
| Tissue-and strain-specific effects of a genotoxic carcinogen 1, 3-butadiene on chromatin and transcription JW Israel, GA Chappell, JM Simon, S Pott, A Safi, L Lewis, P Cotney, ... Mammalian genome 29, 153-167, 2018 | 25 | 2018 |
| Variation in DNA-damage responses to an inhalational carcinogen (1, 3-butadiene) in relation to strain-specific differences in chromatin accessibility and gene transcription … GA Chappell, JW Israel, JM Simon, S Pott, A Safi, K Eklund, KG Sexton, ... Environmental Health Perspectives 125 (10), 107006, 2017 | 24 | 2017 |
| A mouse model of alcoholic liver fibrosis-associated acute kidney injury identifies key molecular pathways S Furuya, GA Chappell, Y Iwata, T Uehara, Y Kato, H Kono, R Bataller, ... Toxicology and applied pharmacology 310, 129-139, 2016 | 23 | 2016 |
| Benefit-risk analysis for foods (BRAFO): evaluation of exposure to dietary nitrates DS Wikoff, C Thompson, J Rager, G Chappell, S Fitch, C Doepker Food and chemical toxicology 120, 709-723, 2018 | 22 | 2018 |
| An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events DM Proctor, M Suh, G Chappell, SJ Borghoff, CM Thompson, K Wiench, ... Regulatory Toxicology and Pharmacology 96, 30-40, 2018 | 20 | 2018 |
| Population-based analysis of DNA damage and epigenetic effects of 1, 3-butadiene in the mouse L Lewis, B Borowa-Mazgaj, A de Conti, GA Chappell, YS Luo, W Bodnar, ... Chemical research in toxicology 32 (5), 887-898, 2019 | 18 | 2019 |
| A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens DS Wikoff, JE Rager, GA Chappell, S Fitch, L Haws, SJ Borghoff Toxicological Sciences 167 (2), 322-335, 2019 | 18 | 2019 |
| Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame SJ Borghoff, SS Cohen, X Jiang, IA Lea, WD Klaren, GA Chappell, JK Britt, ... Food and Chemical Toxicology 172, 113549, 2023 | 16 | 2023 |
Ivan RusynDepartment of Veterinary Physiology and Pharmacology, Texas A&M UniversityVerified email at cvm.tamu.edu
