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Padma Akkapeddi
Padma Akkapeddi
Scientist at Denali Therapeutics Inc.
Verified email at dnli.com
Title
Cited by
Cited by
Year
Small molecular antibacterial peptoid mimics: the simpler the better!
C Ghosh, GB Manjunath, P Akkapeddi, V Yarlagadda, J Hoque, ...
Journal of medicinal chemistry 57 (4), 1428-1436, 2014
2042014
Cleavable cationic antibacterial amphiphiles: synthesis, mechanism of action, and cytotoxicities
J Hoque, P Akkapeddi, V Yarlagadda, DSSM Uppu, P Kumar, J Haldar
Langmuir 28 (33), 12225-12234, 2012
1922012
Construction of homogeneous antibody–drug conjugates using site-selective protein chemistry
P Akkapeddi, SA Azizi, AM Freedy, PMSD Cal, PMP Gois, GJL Bernardes
Chemical Science 7 (5), 2954-2963, 2016
1692016
Membrane active vancomycin analogues: a strategy to combat bacterial resistance
V Yarlagadda, P Akkapeddi, GB Manjunath, J Haldar
Journal of medicinal chemistry 57 (11), 4558-4568, 2014
1652014
Broad spectrum antibacterial and antifungal polymeric paint materials: Synthesis, structure–activity relationship, and membrane-active mode of action
J Hoque, P Akkapeddi, V Yadav, GB Manjunath, DSSM Uppu, MM Konai, ...
ACS applied materials & interfaces 7 (3), 1804-1815, 2015
1532015
Polymers with tunable side-chain amphiphilicity as non-hemolytic antibacterial agents
DSSM Uppu, P Akkapeddi, GB Manjunath, V Yarlagadda, J Hoque, ...
Chemical communications 49 (82), 9389-9391, 2013
1252013
Chemoselective installation of amine bonds on proteins through aza-Michael ligation
AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, ...
Journal of the American Chemical Society 139 (50), 18365-18375, 2017
952017
Glycopeptide antibiotic to overcome the intrinsic resistance of Gram-negative bacteria
V Yarlagadda, GB Manjunath, P Sarkar, P Akkapeddi, K Paramanandham, ...
ACS infectious diseases 2 (2), 132-139, 2016
942016
IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia: An update
ML Oliveira, P Akkapeddi, D Ribeiro, A Melão, JT Barata
Advances in biological regulation 71, 88-96, 2019
892019
Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor
T Rodrigues, M Werner, J Roth, EHG da Cruz, MC Marques, P Akkapeddi, ...
Chemical Science 9 (34), 6899-6903, 2018
732018
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents
B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ...
Nature Protocols 14 (1), 86-99, 2019
632019
A Biodegradable Polycationic Paint that Kills Bacteria in Vitro and in Vivo
J Hoque, P Akkapeddi, C Ghosh, DSSM Uppu, J Haldar
ACS Applied Materials & Interfaces 8 (43), 29298-29309, 2016
572016
A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia
P Akkapeddi, R Fragoso, JA Hixon, AS Ramalho, ML Oliveira, T Carvalho, ...
Leukemia 33 (9), 2155-2168, 2019
482019
From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia
ML Oliveira, P Akkapeddi, I Alcobia, AR Almeida, BA Cardoso, R Fragoso, ...
Cellular signalling 38, 10-25, 2017
352017
Creating MHC-restricted neoantigens with covalent inhibitors that can be targeted by immune therapy
T Hattori, L Maso, KY Araki, A Koide, J Hayman, P Akkapeddi, I Bang, ...
Cancer discovery 13 (1), 132-145, 2023
262023
NRARP displays either pro-or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling
I Pinto, M Duque, J Gonçalves, P Akkapeddi, ML Oliveira, R Cabrita, ...
Oncogene 39 (5), 975-986, 2020
232020
One-pot stapling of interchain disulfides of antibodies using an isobutylene motif
S Sun, P Akkapeddi, MC Marques, N Martínez-Sáez, VM Torres, ...
Organic & Biomolecular Chemistry 17 (7), 2005-2012, 2019
192019
Monobodies as tool biologics for accelerating target validation and druggable site discovery
P Akkapeddi, KW Teng, S Koide
RSC Medicinal Chemistry 12 (11), 1839-1853, 2021
142021
CD98hc is a target for brain delivery of biotherapeutics
KS Chew, RC Wells, A Moshkforoush, D Chan, KJ Lechtenberg, HL Tran, ...
nature communications 14 (1), 5053, 2023
102023
Single mutation on trastuzumab modulates the stability of antibody–drug conjugates built using acetal-based linkers and thiol-maleimide chemistry
X Ferhati, E Jiménez-Moreno, EA Hoyt, G Salluce, M Cabeza-Cabrerizo, ...
Journal of the American Chemical Society 144 (12), 5284-5294, 2022
92022
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