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Dr Mayel Gharanei
Dr Mayel Gharanei
Research Fellow, BC Children's Hospital Research Institute
Verified email at bcchr.ca
Title
Cited by
Cited by
Year
Attenuation of doxorubicin-induced cardiotoxicity by mdivi-1: a mitochondrial division/mitophagy inhibitor
M Gharanei, A Hussain, O Janneh, H Maddock
PloS one 8 (10), e77713, 2013
1272013
Doxorubicin induced myocardial injury is exacerbated following ischaemic stress via opening of the mitochondrial permeability transition pore
M Gharanei, A Hussain, O Janneh, HL Maddock
Toxicology and applied pharmacology 268 (2), 149-156, 2013
682013
Predictivity of in vitro non-clinical cardiac contractility assays for inotropic effects in humans—A literature search
R Wallis, M Gharanei, H Maddock
Journal of Pharmacological and Toxicological Methods 75, 62-69, 2015
222015
Investigation into the cardiotoxic effects of doxorubicin on contractile function and the protection afforded by cyclosporin A using the work-loop assay
M Gharanei, A Hussain, RS James, O Janneh, H Maddock
Toxicology in vitro 28 (5), 722-731, 2014
132014
The cardiac work-loop technique: An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles
S Fletcher, H Maddock, RS James, R Wallis, M Gharanei
Scientific Reports 10 (1), 5258, 2020
102020
15 mitochondrial division inhibitor-1 protects against doxorubicin-induced cardiotoxicity
M Gharanei, A Hussain, O Janneh, HL Maddock
Heart 100 (Suppl 1), A6-A6, 2014
62014
Metformin protects against sunitinib-induced cardiotoxicity: Investigating the role of AMPK
R Kuburas, M Gharanei, I Haussmann, H Maddock, H Sandhu
Journal of Cardiovascular Pharmacology 79 (6), 799-807, 2022
42022
The cardiac work-loop technique to assess drug-induced changes in cardiac contractility
S Fletcher, R James, R Wallis, H Maddock, M Gharanei
Journal of Pharmacological and Toxicological Methods 99 (Sept-Oct 2019), 106595, 2019
22019
Physiological work-loop contractions using isolated myocytes
M Gharanei, A Linekar, O Chuizbaian, R Wallis, H Maddock
Journal of Pharmacological and Toxicological Methods 99, 106595, 2019
22019
Antioxidant Tiron Protects Against Doxorubicin-Induced Cardiotoxicity
O Chiuzbaian, M Gharanei, CJ Mee, H Maddock, E Hatch
Journal of Pharmacological and Toxicological Methods 88, 216, 2017
12017
20 Cardioprotection During Chemotherapy: A Case Study to Understand Intracellular Mechanisms to Combat the Cardiotoxicity of Sunitinib
H Sandhu, S Cooper, M Eckert, L Pisula, C Chinweike, M Gharanei, ...
Heart 100 (Suppl 1), A7-A8, 2014
12014
Measuring the impact of known inotropes on rat papillary muscles via the force-clamped feedback work-loop
S Fletcher, H Maddock, R Wallis, RS James, M Gharanei
Journal of Pharmacological and Toxicological Methods 111, 107009, 2021
2021
Primary cardiomyocyte work-loop assay to predict inotropic drug effects of checkpoint kinase inhibitors
M Gharanei, J Billson, O Blair, J Hurst, A Linekar, R Wallis, H Maddock
Journal of Pharmacological and Toxicological Methods 105, 106758, 2020
2020
An in vitro platform using the human and rat primary cardiomyocyte work loop assay to screen for drug-induced effects on cardiac contractility
M Gharanei, J Billson, O Blair, J Hurst, A Linekar, R Wallis, H Maddock
Journal of Pharmacological and Toxicological Methods 105, 106759, 2020
2020
The cardiac work-loop technique: An in vitro model for profiling drug-induced changes in cardiac contractility using rat papillary muscles
S Fletcher, M Gharanei, H Maddock, R James
BRITISH JOURNAL OF PHARMACOLOGY 177 (11), 2622-2623, 2020
2020
The role of AMPK signalling during metformin co-administration with sunitinib
R Kuburas, M Gharanei, I Haussmann, H Maddock, H Sandhu
BRITISH JOURNAL OF PHARMACOLOGY 176 (16), 2991-2992, 2019
2019
Development of an in vitro platform using the human primary cardiomyocyte work loop assay to screen for drug-induced effects on cardiac contractility
M Gharanei, M Bonner, A Linekar, R Wallis, O Chuizbaian, H Maddock
Journal of Pharmacological and Toxicological Methods 93, 127, 2018
2018
P37 The assessment of the cardioprotective properties of metformin during sunitinib-induced cytotoxicity
R Kuburas, M Gharanei, I Haussmann, H Maddock, H Sandhu
Heart 104 (Suppl 3), A14-A14, 2018
2018
An In Vitro Assay for Assessing Cardiac Contractility Effects of Test Compounds Using the Human Trabeculae Muscle Work Loop Assay
M Gharanei, R Wallis, A Linekar, M Bonner, M Babba, H Maddock
Journal of Pharmacological and Toxicological Methods 88, 227, 2017
2017
The Early Assessment of the Cardioprotective Properties of Metformin during Sunitinib-Induced Cytotoxicity
R Kuburas, M Gharanei, I Haussmann, H Maddock, H Sandhu
Journal of Pharmacological and Toxicological Methods 88, 218, 2017
2017
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