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Anthony Young
Anthony Young
Sóliome, University of Utah, University of Arizona
Verified email at soliome.com
Title
Cited by
Cited by
Year
Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism
DP Dowling, NA Bruender, AP Young, RM McCarty, V Bandarian, ...
Nature chemical biology 10 (2), 106-112, 2014
902014
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine
AP Young, V Bandarian
Biochemistry 50 (49), 10573-10575, 2011
462011
Chemical and Biological Reduction of the Radical SAM Enzyme CPH4 Synthase
NA Bruender, AP Young, V Bandarian
Biochemistry 54 (18), 2903-2910, 2015
392015
Radical mediated ring formation in the biosynthesis of the hypermodified tRNA base wybutosine
AP Young, V Bandarian
Current opinion in chemical biology 17 (4), 613-618, 2013
272013
Mechanistic Studies of the Radical S-Adenosyl-l-methionine Enzyme 4-Demethylwyosine Synthase Reveal the Site of Hydrogen Atom Abstraction
AP Young, V Bandarian
Biochemistry 54 (23), 3569-3572, 2015
182015
Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1
TAJ Grell, AP Young, CL Drennan, V Bandarian
2018 140, 6842-6852, 0
17*
TYW1: A Radical SAM Enzyme Involved in the Biosynthesis of Wybutosine Bases
AP Young, V Bandarian
Methods in Enzymology 606, 119-153, 2018
162018
New role for radical SAM enzymes in the biosynthesis of thio (seleno) oxazole RiPP natural products
JK Lewis, AS Jochimsen, SJ Lefave, AP Young, WM Kincannon, ...
Biochemistry 60 (45), 3347-3361, 2021
132021
Human Viperin Causes Radical SAM-Dependent Elongation of Escherichia coli, Hinting at its Physiological Role
MT Nelp, AP Young, BM Stepanski, V Bandarian
Biochemistry 56 (30), 3874-3876, 2017
132017
Eukaryotic TYW1 is a radical SAM flavoenzyme
AP Young, V Bandarian
Biochemistry 60 (27), 2179-2185, 2021
92021
Elucidation of the substrate of tRNA-modifying enzymes MnmEG leads to in vitro reconstitution of an evolutionarily conserved uridine hypermodification
P Bommisetti, A Young, V Bandarian
Journal of Biological Chemistry 298 (11), 2022
52022
Insertion of 4-Demethylwyosine in tRNAPhe Catalyzed by the Radical S-Adenosyl-l-methionine Enzyme TYW1 Entails Oxidative Cleavage of Pyruvate to Form CO2
AP Young, V Bandarian
Biochemistry 61 (23), 2643-2647, 2022
2022
Redox Mediated Modifications of tRNA Bases
AP Young, V Bandarian
Elsevier, 2020
2020
Characterization of 4-demethylwyosine synthase, a radical S-adenosyl-L-methionine enzyme involved in the modification of tRNA
AP Young
The University of Arizona, 2016
2016
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