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Eugene Serebryany
Eugene Serebryany
Harvard University; SUNY Stony Brook
Verified email at stonybrook.edu
Title
Cited by
Cited by
Year
Artificial membrane-like environments for in vitro studies of purified G-protein coupled receptors
E Serebryany, GA Zhu, ECY Yan
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (2), 225-233, 2012
1262012
The βγ-crystallins: Native state stability and pathways to aggregation
E Serebryany, JA King
Progress in biophysics and molecular biology 115 (1), 32-41, 2014
1072014
An Internal Disulfide Locks a Misfolded Aggregation-Prone Intermediate in Cataract-Linked Mutants of Human γD-Crystallin
E Serebryany, JC Woodard, BV Adkar, M Shabab, JA King, ...
Journal of Biological Chemistry 291 (36), 19172-19183, 2016
712016
Copper and zinc ions specifically promote nonamyloid aggregation of the highly stable human γ-D crystallin
L Quintanar, JA Domínguez-Calva, E Serebryany, L Rivillas-Acevedo, ...
ACS Chemical Biology 11 (1), 263-272, 2016
612016
Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation
E Serebryany, S Yu, SA Trauger, B Budnik, EI Shakhnovich
Journal of Biological Chemistry 293 (46), 17997-18009, 2018
572018
Calcium-dependent ligand binding and G-protein signaling of family B GPCR parathyroid hormone 1 receptor purified in nanodiscs
N Mitra, Y Liu, J Liu, E Serebryany, V Mooney, BT DeVree, RK Sunahara, ...
ACS chemical biology 8 (3), 617-625, 2013
542013
Aggregation of Trp>Glu Point Mutants of Human Gamma-D Crystallin Provides a Model for Hereditary or UV-Induced Cataract
E Serebryany, T Takata, E Erickson, N Schafheimer, Y Wang, JA King
Protein Science, 2016
532016
Wild-type Human γD-crystallin Promotes Aggregation of Its Oxidation-mimicking, Misfolding-prone W42Q Mutant
E Serebryany, JA King
Journal of Biological Chemistry 290 (18), 11491-11503, 2015
382015
Mercury-induced aggregation of human lens γ-crystallins reveals a potential role in cataract disease
JA Domínguez-Calva, ML Pérez-Vázquez, E Serebryany, JA King, ...
JBIC Journal of Biological Inorganic Chemistry 23 (7), 1105-1118, 2018
312018
Kinetic Stability of Long-Lived Human Lens γ-Crystallins and Their Isolated Double Greek Key Domains
IA Mills-Henry, SL Thol, MS Kosinski-Collins, E Serebryany, JA King
Biophysical journal 117 (2), 269-280, 2019
262019
A Histidine Switch for Zn-Induced Aggregation of γ-Crystallins Reveals a Metal-Bridging Mechanism That Is Relevant to Cataract Disease
JA Domínguez-Calva, C Haase-Pettingell, E Serebryany, JA King, ...
Biochemistry 57 (33), 4959-4962, 2018
232018
Redox chemistry of lens crystallins: A system of cysteines
E Serebryany, DC Thorn, L Quintanar
Experimental Eye Research 211, 108707, 2021
172021
A native chemical chaperone in the human eye lens
E Serebryany, S Chowdhury, CN Woods, DC Thorn, NE Watson, ...
Elife 11, e76923, 2022
102022
Homodimerization enhances both sensitivity and dynamic range of the ligand‐binding domain of type 1 metabotropic glutamate receptor
E Serebryany, E Folta‐Stogniew, J Liu, ECY Yan
FEBS letters 590 (23), 4308-4317, 2016
52016
Copper Reductase Activity and Free Radical Chemistry by Cataract-Associated Human Lens γ-Crystallins
G Palomino-Vizcaino, N Schuth, JA Domínguez-Calva, ...
Journal of the American Chemical Society, 2022
42022
Conformational catalysis of cataract-associated aggregation in a human eye lens crystallin occurs via interface stealing.
E Serebryany, WM Jacobs, R Razban, E Shakhnovich
bioRxiv, 601708, 2019
42019
Conformational catalysis of cataract-associated aggregation by interacting intermediates in a human eye lens crystallin
E Serebryany, R Razban, EI Shakhnovich
arXiv preprint arXiv:1904.03653, 2019
32019
Systematic conformation-to-phenotype mapping via limited deep sequencing of proteins
E Serebryany, VY Zhao, K Park, A Bitran, SA Trauger, B Budnik, ...
Molecular Cell 83 (11), 1936-1952. e7, 2023
12023
Buried Tryptophans Contributing to the High Kinetic Stability of the Long-lived Gamma Crystallins and their Oxidative Damage Opening the Pathway to the Aggregated State …
J King, IM Henry, M Kosinski-Collins, S Thol, E Serebryany
Biophysical Journal 118 (3), 181a, 2020
12020
Kinetic Stability of Long-Lived Human γ-D and γS Lens Crystallins, Derived in Part from their Domain Interfaces, May Protect against Cataract
IM Henry, M Kosinski-Collins, S Thol, E Serebryany, JA King
Biophysical Journal 116 (3), 321a-322a, 2019
12019
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