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Qin Yang
Qin Yang
Aptitude Medical Systems
Verified email at crystal.harvard.edu
Title
Cited by
Cited by
Year
Crystal structure of a human cleavage factor CFIm25/CFIm68/RNA complex provides an insight into poly (A) site recognition and RNA looping
Q Yang, M Coseno, GM Gilmartin, S Doublié
Structure 19 (3), 368-377, 2011
1602011
Structural basis of UGUA recognition by the Nudix protein CFIm25 and implications for a regulatory role in mRNA 3′ processing
Q Yang, GM Gilmartin, S Doublié
Proceedings of the National Academy of Sciences 107 (22), 10062-10067, 2010
1532010
Multiparameter particle display (MPPD): a quantitative screening method for the discovery of highly specific aptamers
J Wang, J Yu, Q Yang, J McDermott, A Scott, M Vukovich, R Lagrois, ...
Angewandte Chemie 129 (3), 762-765, 2017
842017
Real-time monitoring of a protein biomarker
C Parolo, A Idili, G Ortega, A Csordas, A Hsu, N Arroyo-Currás, Q Yang, ...
ACS sensors 5 (7), 1877-1881, 2020
742020
Machine learning guided aptamer refinement and discovery
A Bashir, Q Yang, J Wang, S Hoyer, W Chou, C McLean, G Davis, Q Gong, ...
Nature Communications 12 (1), 2366, 2021
722021
Structural biology of poly (A) site definition
Q Yang, S Doublié
Wiley Interdisciplinary Reviews: RNA 2 (5), 732-747, 2011
622011
The structure of human Cleavage Factor Im hints at functions beyond UGUA-specific RNA binding: A role in alternative polyadenylation and a potential link to 5 …
Q Yang, GM Gilmartin, S Doublié
RNA biology 8 (5), 748-753, 2011
622011
Substrate-modulated ADP/ATP-transporter dynamics revealed by NMR relaxation dispersion
S Brüschweiler, Q Yang, C Run, JJ Chou
Nature structural & molecular biology 22 (8), 636-641, 2015
562015
A self-sequestered calmodulin-like Ca2+ sensor of mitochondrial SCaMC carrier and its implication to Ca2+-dependent ATP-Mg/Pi transport
Q Yang, S Brüschweiler, JJ Chou
Structure 22 (2), 209-217, 2014
312014
Crystal structure of human poly (A) polymerase gamma reveals a conserved catalytic core for canonical poly (A) polymerases
Q Yang, LWM Nausch, G Martin, W Keller, S Doublié
Journal of molecular biology 426 (1), 43-50, 2014
232014
Molecular basis of MgATP selectivity of the mitochondrial SCaMC carrier
C Run, Q Yang, Z Liu, B OuYang, JJ Chou
Structure 23 (8), 1394-1403, 2015
212015
Purification, crystallization and preliminary X-ray diffraction of a disulfide cross-linked complex between bovine poly (A) polymerase and a chemically modified 15-mer oligo (A …
Q Yang, F Faucher, M Coseno, J Heckman, S Doublié
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011
72011
Development of an aptamer-based electrochemical microfluidic device for viral vaccine quantitation
T Chozinski, BS Ferguson, W Fisher, S Ge, Q Gong, H Kang, J McDermott, ...
Analytical Chemistry 94 (16), 6146-6155, 2022
42022
Purification, crystallization and preliminary X-ray diffraction of the N-terminal calmodulin-like domain of the human mitochondrial ATP-Mg/Pi carrier SCaMC1
Q Yang, S Brüschweiler, JJ Chou
Acta Crystallographica Section F: Structural Biology Communications 70 (1 …, 2014
32014
A bispecific aptamer targeting both VEGF and angiopoietin-2 for treating retinal diseases
S Ferguson, DA Long, Q Yang, H Kang, J Yu, WC Chou, M Vukovich, ...
Investigative Ophthalmology & Visual Science 60 (9), 3665-3665, 2019
22019
MightyScreen: an open-source visualization application for screening data analysis
L Wang, Q Yang, A Jaimes, T Wang, H Strobelt, J Chen, P Sliz
SLAS DISCOVERY: Advancing Life Sciences R&D 23 (2), 218-223, 2018
22018
Protocol to generate DNA aptamer coated particles and utilization for affinity-based screening with particle display
Q Yang, A Bashir, J Wang, S Hoyer, W Chou, C McLean, G Davis, Q Gong, ...
12021
Aptamers and use thereof
W Jinpeng, Q Gong, H Kang, Q Yang, B Ferguson
US Patent App. 17/801,635, 2023
2023
Aptamers and use thereof
W Jinpeng, Q Yang, H Kang, Q Gong, BS Ferguson
US Patent App. 17/463,853, 2022
2022
Compositions, methods and systems for identifying candidate nucleic acid agent
W Jinpeng, Q Yang, Q Gong
US Patent 11,248,231, 2022
2022
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