| Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming Y Gao, J Chen, K Li, T Wu, B Huang, W Liu, X Kou, Y Zhang, H Huang, ... Cell stem cell 12 (4), 453-469, 2013 | 398 | 2013 |
| Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation W Yuan, T Wu, H Fu, C Dai, H Wu, N Liu, X Li, M Xu, Z Zhang, T Niu, ... science 337 (6097), 971-975, 2012 | 311 | 2012 |
| Engineering pulmonary vasculature in decellularized rat and human lungs X Ren, PT Moser, SE Gilpin, T Okamoto, T Wu, LF Tapias, FE Mercier, ... Nature biotechnology 33 (10), 1097-1102, 2015 | 243 | 2015 |
| Bioengineering human lung grafts on porcine matrix H Zhou, K Kitano, X Ren, TK Rajab, M Wu, SE Gilpin, T Wu, L Baugh, ... Annals of surgery 267 (3), 590-598, 2018 | 103 | 2018 |
| Reprogramming of trophoblast stem cells into pluripotent stem cells by Oct4 T Wu, H Wang, J He, L Kang, Y Jiang, J Liu, Y Zhang, Z Kou, L Liu, ... Stem cells 29 (5), 755-763, 2011 | 87 | 2011 |
| Regenerative potential of human airway stem cells in lung epithelial engineering SE Gilpin, JM Charest, X Ren, LF Tapias, T Wu, D Evangelista-Leite, ... Biomaterials 108, 111-119, 2016 | 75 | 2016 |
| Mice cloned from induced pluripotent stem cells (iPSCs) Z Kou, L Kang, Y Yuan, Y Tao, Y Zhang, T Wu, J He, J Wang, Z Liu, S Gao Biology of reproduction 83 (2), 238-243, 2010 | 63 | 2010 |
| An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors J He, L Kang, T Wu, J Zhang, H Wang, H Gao, Y Zhang, B Huang, W Liu, ... Stem cells and development 21 (14), 2630-2641, 2012 | 53 | 2012 |
| Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation L Kang, T Wu, Y Tao, Y Yuan, J He, Y Zhang, T Luo, Z Kou, S Gao Cell research 21 (3), 546-549, 2011 | 40 | 2011 |
| Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro JJ Tan, JP Guyette, K Miki, L Xiao, G Kaur, T Wu, L Zhu, KJ Hansen, ... Nature communications 12 (1), 4997, 2021 | 28 | 2021 |
| Metabolic glycan labeling and chemoselective functionalization of native biomaterials X Ren, D Evangelista-Leite, T Wu, TK Rajab, PT Moser, K Kitano, ... Biomaterials 182, 127-134, 2018 | 21 | 2018 |
| A fully automated high-throughput bioreactor system for lung regeneration DE Gorman, T Wu, SE Gilpin, HC Ott Tissue Engineering Part C: Methods 24 (11), 671-678, 2018 | 14 | 2018 |
| Xist Deficiency and Disorders of X-Inactivation in Rabbit Embryonic Stem Cells Can Be Rescued by Transcription-Factor-Mediated Conversion Y Jiang, Z Kou, T Wu, W An, R Zhou, H Wang, Y Gao, S Gao Stem Cells and Development 23 (19), 2283-2296, 2014 | 12 | 2014 |
| High-throughput culture method of induced pluripotent stem cell-derived alveolar epithelial cells D Becerra, T Wu, S Jeffs, HC Ott Tissue Engineering Part C: Methods 27 (12), 639-648, 2021 | 5 | 2021 |
| Protease inhibitor Camostat Mesyalte blocks wild type SARS-CoV-2 and D614G viral entry in human engineered miniature lungs T Wu, SA Rabi, WA Michaud, D Becerra, SE Gilpin, M Mino-Kenudson, ... Biomaterials 285, 121509, 2022 | 4 | 2022 |
| Engineering bioartificial lungs for transplantation T Wu, KP Economopoulos, HC Ott Current Stem Cell Reports 3, 55-67, 2017 | 4 | 2017 |
| Intratracheally injected human-induced pluripotent stem cell-derived pneumocytes and endothelial cells engraft in the distal lung and ameliorate emphysema in a rat model W Altalhi, T Wu, GR Wojtkiewicz, S Jeffs, K Miki, HC Ott The Journal of Thoracic and Cardiovascular Surgery 166 (1), e23-e37, 2023 | 1 | 2023 |
| High-throughput culture method of induced pluripotent stem cell derived alveolar epithelial cells using floating matrigel droplets DC Becerra, S Jeffs, T Wu, H Ott The Journal of Heart and Lung Transplantation 40 (4), S52, 2021 | 1 | 2021 |
| Engineering distal pulmonary epithelium from induced pluripotent stem cell (iPSC)-derived alveolar cells S Gilpin, T Wu, D Gorman, L Zhu, D Evangelista-Leite, M Vedaie, D Kotton, ... European Respiratory Journal 54 (suppl 63), 2019 | 1 | 2019 |
| Distal Lung Epithelial Regeneration is Driven by Notch Pathway Inhibition and Enhanced by Ex Vivo Native Lung Scaffold Biomimetic Culture S Gilpin, D Gorman, L Zhu, T Wu, H Ott European Respiratory Journal 54 (suppl 63), 2019 | | 2019 |
Harald C OttHarvard Medical School, Massachusetts General Hospital Verified email at partners.org
