| Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species F González-Lizárraga, SB Socías, CL Ávila, CM Torres-Bugeau, ... Scientific reports 7 (1), 1-13, 2017 | 117 | 2017 |
| Tetracycline repurposing in neurodegeneration: focus on Parkinson’s disease M Bortolanza, GC Nascimento, SB Socias, D Ploper, RN Chehín, ... Journal of neural transmission 125, 1403-1415, 2018 | 82 | 2018 |
| Thermal and pH-induced conformational changes of a β-sheet protein monitored by infrared spectroscopy R Chehín, I Iloro, MJ Marcos, E Villar, VL Shnyrov, JLR Arrondo Biochemistry 38 (5), 1525-1530, 1999 | 79 | 1999 |
| Evidence for Cu (I)-thiolate ligation and prediction of a putative copper-binding site in the Escherichia coli NADH dehydrogenase-2 VA Rapisarda, RN Chehı́n, J De Las Rivas, L Rodrı́guez-Montelongo, ... Archives of biochemistry and biophysics 405 (1), 87-94, 2002 | 68 | 2002 |
| Rifampicin and its derivative rifampicin quinone reduce microglial inflammatory responses and neurodegeneration induced in vitro by α-synuclein fibrillary aggregates L Acuña, S Hamadat, NS Corbalán, F González-Lizárraga, ... Cells 8 (8), 776, 2019 | 55 | 2019 |
| Tyrosine hydroxylase binds tetrahydrobiopterin cofactor with negative cooperativity, as shown by kinetic analyses and surface plasmon resonance detection T Flatmark, B Almås, PM Knappskog, SV Berge, RM Svebak, R Chehin, ... European journal of biochemistry 262 (3), 840-849, 1999 | 51 | 1999 |
| Microglial glutamate release evoked by α‐synuclein aggregates is prevented by dopamine M dos‐Santos‐Pereira, L Acuña, S Hamadat, J Rocca, ... Glia 66 (11), 2353-2365, 2018 | 50 | 2018 |
| Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo A Dominguez-Meijide, V Parrales, E Vasili, F González-Lizárraga, ... Neurobiology of Disease 151, 105256, 2021 | 49 | 2021 |
| Domain structure and stability of human phenylalanine hydroxylase inferred from infrared spectroscopy R Chehin, M Thorolfsson, PM Knappskog, A Martinez, T Flatmark, ... FEBS letters 422 (2), 225-230, 1998 | 49 | 1998 |
| Exploiting the therapeutic potential of ready-to-use drugs: Repurposing antibiotics against amyloid aggregation in neurodegenerative diseases SB Socias, F Gonzalez-Lizarraga, CL Avila, C Vera, L Acuña, ... Progress in neurobiology 162, 17-36, 2018 | 42 | 2018 |
| Long-term analysis of antibodies elicited by SPUTNIK V: A prospective cohort study in Tucumán, Argentina RE Chahla, RH Tomas-Grau, SI Cazorla, D Ploper, EV Pingitore, ... The Lancet Regional Health–Americas 6, 2022 | 36 | 2022 |
| Structural characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase protofibrils preventing α-synuclein oligomeric species toxicity CL Avila, CM Torres-Bugeau, LRS Barbosa, EM Sales, MO Ouidja, ... Journal of Biological Chemistry 289 (20), 13838-13850, 2014 | 36 | 2014 |
| Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in α-synuclein aggregation CM Torres-Bugeau, CL Ávila, R Raisman-Vozari, D Papy-Garcia, R Itri, ... Journal of Biological Chemistry 287 (4), 2398-2409, 2012 | 33 | 2012 |
| Molecular view by Fourier transform infrared spectroscopy of the relationship between lactocin 705 and membranes: Speculations on antimicrobial mechanism P Castellano, G Vignolo, RN Farías, JL Arrondo, R Chehín Applied and environmental microbiology 73 (2), 415-420, 2007 | 29 | 2007 |
| Methionine adenosyltransferase α-helix structure unfolds at lower temperatures than β-sheet: A 2D-IR study I Iloro, R Chehín, FM Goni, MA Pajares, JLR Arrondo Biophysical journal 86 (6), 3951-3958, 2004 | 29 | 2004 |
| Protein-induced fusion of phospholipid vesicles of heterogeneous sizes BF De Arcuri, GF Vechetti, RN Chehın, FM Goni, RD Morero Biochemical and biophysical research communications 262 (3), 586-590, 1999 | 27 | 1999 |
| Towards efficient biocatalysts: photo-immobilization of a lipase on novel lysozyme amyloid-like nanofibrils S Chaves, LM Pera, CL Avila, CM Romero, M Baigori, FEM Vieyra, ... RSC advances 6 (11), 8528-8538, 2016 | 26 | 2016 |
| Differential transmembrane diffusion of triiodothyronine and thyroxine in liposomes: regulation by lipid composition RN Chehin, BG Isse, MR Rintoul, RN Farias The Journal of membrane biology 167, 251-256, 1999 | 25 | 1999 |
| Early stages of LDL oxidation: apolipoprotein B structural changes monitored by infrared spectroscopy R Chehin, D Rengel, JCG Milicua, FM Goñi, JLR Arrondo, G Pifat Journal of Lipid Research 42 (5), 778-782, 2001 | 24 | 2001 |
| pH-dependent thermal transitions of lentil lectin MJ Marcos, R Chehı́n, JL Arrondo, GG Zhadan, E Villar, VL Shnyrov FEBS letters 443 (2), 192-196, 1999 | 22 | 1999 |
