| Isoform-selective histone deacetylase inhibitors AV Bieliauskas, MKH Pflum Chemical Society Reviews 37 (7), 1402-1413, 2008 | 409 | 2008 |
| Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation MKH Pflum, JK Tong, WS Lane, SL Schreiber Journal of Biological Chemistry 276 (50), 47733-47741, 2001 | 335 | 2001 |
| Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax AM Baranger, CR Palmer, MK Hamm, HA Giebler, A Brauweiler, ... Nature 376 (6541), 606-608, 1995 | 205 | 1995 |
| Kinase-catalyzed biotinylation for phosphoprotein detection KD Green, MKH Pflum Journal of the American Chemical Society 129 (1), 10-11, 2007 | 125 | 2007 |
| Phosphorylation-dependent kinase–substrate cross-linking S Suwal, MKH Pflum Angewandte Chemie (International ed. in English) 49 (9), 1627, 2010 | 79 | 2010 |
| Residues in the 11 Å channel of histone deacetylase 1 promote catalytic activity: implications for designing isoform-selective histone deacetylase inhibitors SVW Weerasinghe, G Estiu, O Wiest, MKH Pflum Journal of medicinal chemistry 51 (18), 5542-5551, 2008 | 71 | 2008 |
| Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid AV Bieliauskas, SVW Weerasinghe, MKH Pflum Bioorganic & medicinal chemistry letters 17 (8), 2216-2219, 2007 | 71 | 2007 |
| Mutagenesis studies of the 14 Å internal cavity of histone deacetylase 1: insights toward the acetate-escape hypothesis and selective inhibitor design MK Wambua, DA Nalawansha, AT Negmeldin, MKH Pflum Journal of medicinal chemistry 57 (3), 642-650, 2014 | 57 | 2014 |
| Exploring kinase cosubstrate promiscuity: monitoring kinase activity through dansylation KD Green, MKH Pflum Chembiochem: a European journal of chemical biology 10 (2), 234, 2009 | 54 | 2009 |
| LSD1 substrate binding and gene expression are affected by HDAC1-mediated deacetylation DA Nalawansha, MKH Pflum ACS chemical biology 12 (1), 254-264, 2017 | 50 | 2017 |
| The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity AT Negmeldin, JR Knoff, MKH Pflum European journal of medicinal chemistry 143, 1790-1806, 2018 | 45 | 2018 |
| Structural requirements of HDAC inhibitors: SAHA analogues modified at the C2 position display HDAC6/8 selectivity AT Negmeldin, G Padige, AV Bieliauskas, MKH Pflum ACS Medicinal Chemistry Letters 8 (3), 281-286, 2017 | 45 | 2017 |
| A cell‐permeable ATP analogue for kinase‐catalyzed biotinylation AE Fouda, MKH Pflum Angewandte Chemie International Edition 54 (33), 9618-9621, 2015 | 42 | 2015 |
| HDAC inhibitor-induced mitotic arrest is mediated by Eg5/KIF11 acetylation DA Nalawansha, ID Gomes, MK Wambua, MKH Pflum Cell chemical biology 24 (4), 481-492. e5, 2017 | 40 | 2017 |
| The structural requirements of histone deacetylase inhibitors: Suberoylanilide hydroxamic acid analogs modified at the C3 position display isoform selectivity SE Choi, SVW Weerasinghe, MKH Pflum Bioorganic & medicinal chemistry letters 21 (20), 6139-6142, 2011 | 39 | 2011 |
| Phosphopeptide Modification and Enrichment by Oxidation–Reduction Condensation M Warthaka, P Karwowska-Desaulniers, MKH Pflum ACS chemical biology 1 (11), 697-701, 2006 | 39 | 2006 |
| Largazole analogues embodying radical changes in the depsipeptide ring: Development of a more selective and highly potent analogue J Almaliti, AA Al-Hamashi, AT Negmeldin, CL Hanigan, L Perera, ... Journal of medicinal chemistry 59 (23), 10642-10660, 2016 | 35 | 2016 |
| The structural requirements of histone deacetylase inhibitors: Suberoylanilide hydroxamic acid analogs modified at the C6 position SE Choi, MKH Pflum Bioorganic & medicinal chemistry letters 22 (23), 7084-7086, 2012 | 33 | 2012 |
| A comparative study of ATP analogs for phosphorylation-dependent kinase–substrate crosslinking S Garre, C Senevirathne, MKH Pflum Bioorganic & medicinal chemistry 22 (5), 1620-1625, 2014 | 30 | 2014 |
| Cyclic AMP response element-binding protein (CREB) and CAAT/enhancer-binding protein β (C/EBPβ) bind chimeric DNA sites with high affinity JR Flammer, KN Popova, MKH Pflum Biochemistry 45 (31), 9615-9623, 2006 | 30 | 2006 |
