Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients LA Videla, R Rodrigo, M Orellana, V Fernandez, G Tapia, L Quiñones, ... Clinical science 106 (3), 261-268, 2004 | 600 | 2004 |
CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people L Quinones, D Lucas, J Godoy, D Cáceres, F Berthou, N Varela, K Lee, ... Cancer letters 174 (1), 35-44, 2001 | 175 | 2001 |
Relationship between in vivo chlorzoxazone hydroxylation, hepatic cytochrome P450 2E1 content and liver injury in obese non-alcoholic fatty liver disease patients M Orellana, R Rodrigo, N Varela, J Araya, J Poniachik, A Csendes, ... Hepatology research 34 (1), 57-63, 2006 | 101 | 2006 |
Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations L Quinones, F Berthou, N Varela, B Simon, L Gil, D Lucas Cancer letters 141 (1-2), 167-171, 1999 | 89 | 1999 |
Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs in the Chilean population: comparison with Caucasian and Asian … Á Roco, L Quiñones, JAG Agúndez, E García-Martín, V Squicciarini, ... Frontiers in genetics 3, 229, 2012 | 85 | 2012 |
Impaired cell cycle regulation of the osteoblast‐related heterodimeric transcription factor Runx2‐Cbfβ in osteosarcoma cells IA San Martin, N Varela, M Gaete, K Villegas, M Osorio, JC Tapia, ... Journal of cellular physiology 221 (3), 560-571, 2009 | 72 | 2009 |
Joint effect among p53, CYP1A1, GSTM1 polymorphism combinations and smoking on prostate cancer risk: an exploratory genotype‐environment interaction study LA Quiñones, CE Irarrázabal, CR Rojas, CE Orellana, C Acevedo, ... Asian Journal of andrology 8 (3), 349-355, 2006 | 69 | 2006 |
Relationship among metabolizing genes, smoking and alcohol used as modifier factors on prostate cancer risk: exploring some gene–gene and gene–environment interactions DD Cáceres L, J Iturrieta G, C Acevedo C, C Huidobro A, N Varela F, ... European journal of epidemiology 20, 79-88, 2005 | 54 | 2005 |
Study of cytochrome P450 2E1 and its allele variants in liver injury of nondiabetic, nonalcoholic steatohepatitis obese women NM Varela, LA Quiñones, M Orellana, J Poniachik, A Csendes, G Smok, ... Biological research 41 (1), 81-92, 2008 | 52 | 2008 |
The cancer‐related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to … F Villanueva, H Araya, P Briceño, N Varela, A Stevenson, S Jerez, ... Journal of cellular physiology 234 (8), 13659-13679, 2019 | 43 | 2019 |
Farmacogenómica como herramienta fundamental para la medicina personalizada: aplicaciones en la práctica clínica L Quiñones, Á Roco, JP Cayún, P Escalante, C Miranda, N Varela, ... Revista médica de Chile 145 (4), 483-500, 2017 | 34 | 2017 |
Characterization of the CYP2D6 drug metabolizing phenotypes of the Chilean mestizo population through polymorphism analyses N Varela, LA Quinones, J Stojanova, J Garay, D Cáceres, S Cespedes, ... Pharmacological Research 101, 124-129, 2015 | 34 | 2015 |
As3MT and GST polymorphisms influencing arsenic metabolism in human exposure to drinking groundwater F González-Martínez, D Sánchez-Rodas, NM Varela, CA Sandoval, ... International Journal of Molecular Sciences 21 (14), 4832, 2020 | 28 | 2020 |
Farmacogenética, tabaco, alcohol y su efecto sobre el riesgo de desarrollar cáncer Á Roco, B Cerda, JP Cayún, A Lavanderos, JC Rubilar, R Cerro, ... Revista chilena de pediatría 89 (4), 432-440, 2018 | 27 | 2018 |
Upregulation of rat liver PPARα‐FGF21 signaling by a docosahexaenoic acid and thyroid hormone combined protocol LA Videla, V Fernández, R Vargas, P Cornejo, G Tapia, N Varela, ... Biofactors 42 (6), 638-646, 2016 | 27 | 2016 |
Clinical applications of pharmacogenomics. L Quiñones, Á Roco, JP Cayún, P Escalante, C Miranda, N Varela, ... Revista médica de Chile 145 (4), 483-500, 2017 | 26 | 2017 |
Mitotic inheritance of mRNA facilitates translational activation of the osteogenic‐Lineage commitment factor runx2 in progeny of osteoblastic cells N Varela, A Aranguiz, C Lizama, H Sepulveda, M Antonelli, R Thaler, ... Journal of cellular physiology 231 (5), 1001-1014, 2016 | 24 | 2016 |
Cancer pharmacogenetics: study of genetically determined variations on cancer susceptibility due to xenobiotic exposure K García1c, L Godoy1c, A Castro1c, J Soto1d, I Saavedra2e, D Cáceres3f Rev Med Chile 134, 499-515, 2006 | 23 | 2006 |
Modulation of rat liver cytochrome P450 activity by prolonged red wine consumption M Orellana, N Varela, V Guajardo, J Araya, R Rodrigo Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2002 | 23 | 2002 |
Allelic variants of cytochrome P4501A1 (CYP1A1), glutathione S transferase M1 (GSTM1) polymorphisms and their association with smoking and alcohol consumption as gastric cancer … K Lee, D Cáceres, N Varela, DA Csendes, RH Rios, SL Quinones Revista Médica de Chile 134 (9), 1107-1115, 2006 | 22 | 2006 |