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Ahmad ELBAHNSI
Ahmad ELBAHNSI
INSERM, CiTCoM UMR8038 CNRS - UPC, Inserm U1268
Adresse e-mail validée de inserm.fr
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Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR
N Baatallah, A Elbahnsi, JP Mornon, B Chevalier, I Pranke, N Servel, ...
Cellular and Molecular Life Sciences 78, 7813-7829, 2021
442021
Combining theoretical and experimental data to decipher CFTR 3D structures and functions
B Hoffmann, A Elbahnsi, P Lehn, JL Décout, F Pietrucci, JP Mornon, ...
Cellular and molecular life sciences 75, 3829-3855, 2018
252018
Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium
A Mehregan, S Pérez-Conesa, Y Zhuang, A Elbahnsi, D Pasini, E Lindahl, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1864 (10), 183994, 2022
21*2022
Holding the nucleosome together: a quantitative description of the DNA–histone interface in solution
A Elbahnsi, R Retureau, M Baaden, B Hartmann, C Oguey
Journal of chemical theory and computation 14 (2), 1045-1058, 2018
212018
Simulations meet experiment to reveal new insights into DNA intrinsic mechanics
A Ben Imeddourene, A Elbahnsi, M Guéroult, C Oguey, N Foloppe, ...
PLoS Computational Biology 11 (12), e1004631, 2015
212015
Molecular model of the ferroportin intracellular gate and implications for the human iron transport cycle and hemochromatosis type 4A
J Guellec, A Elbahnsi, ML Tertre, K Uguen, I Gourlaouen, C Férec, C Ka, ...
The FASEB Journal 33 (12), 14625-14635, 2019
172019
Structural explorations of NCp7–nucleic acid complexes give keys to decipher the binding process
R Retureau, C Oguey, O Mauffret, B Hartmann
Journal of molecular biology 431 (10), 1966-1980, 2019
172019
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity
L Froux, A Elbahnsi, B Boucherle, A Billet, N Baatallah, B Hoffmann, ...
European Journal of Medicinal Chemistry 190, 112116, 2020
152020
High-resolution biophysical analysis of the dynamics of nucleosome formation
A Hatakeyama, B Hartmann, A Travers, C Nogues, M Buckle
Scientific reports 6 (1), 27337, 2016
142016
New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation
S Bitam, A Elbahnsi, G Creste, I Pranke, B Chevalier, F Berhal, ...
Scientific reports 11 (1), 6842, 2021
92021
Functional and pharmacological characterization of the rare CFTR mutation W361R
A Billet, A Elbahnsi, M Jollivet-Souchet, B Hoffmann, JP Mornon, ...
Frontiers in Pharmacology 11, 295, 2020
92020
Structure and sequence-based computational approaches to allosteric signal transduction: application to electromechanical coupling in voltage-gated ion channels
A Elbahnsi, L Delemotte
Journal of Molecular Biology 433 (17), 167095, 2021
52021
A dynamic view of DNA structure within the nucleosome: Biological implications
R Retureau, N Foloppe, A Elbahnsi, C Oguey, B Hartmann
Journal of structural biology 211 (1), 107511, 2020
42020
Interplay between VSD, pore, and membrane lipids in electromechanical coupling in HCN channels
A Elbahnsi, J Cowgill, V Burtscher, L Wedemann, L Zeckey, B Chanda, ...
Elife 12, e80303, 2023
32023
Insights into the Role of the Discontinuous TM7 Helix of Human Ferroportin through the Prism of the Asp325 Residue
M Le Tertre, A Elbahnsi, C Ka, I Callebaut, G Le Gac
International Journal of Molecular Sciences 22 (12), 6412, 2021
22021
Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases
JL Delaunay, A Elbahnsi, A Bruneau, C Madry, AM Durand-Schneider, ...
International Journal of Molecular Sciences 24 (2), 1236, 2023
12023
Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants
N Baatallah, A Elbahnsi, B Chevalier, S Castanier, JP Mornon, I Pranke, ...
International Journal of Molecular Sciences 23 (24), 16225, 2022
12022
CFTR corrector efficacy is associated with occupancy of distinct binding sites
N Baatallah, A Elbahnsi, JP Mornon, B Chevalier, I Pranke, N Servel, ...
bioRxiv, 2021.05. 04.442442, 2021
12021
Insights into the role of glycerophospholipids on the iron export function of SLC40A1 and the molecular mechanisms of ferroportin disease.
R Debbiche, A Elbahnsi, K Uguen, C Ka, I Callebaut, G Le Gac
bioRxiv, 2024.02. 05.578958, 2024
2024
689 Pharmacological chaperones improve intradomain stability and interdomain assembly via distinct binding sites to rescue misfolded cystic fibrosis transmembrane conductance …
N Baatallah, A Elbahnsi, J Mornon, B Chevalier, I Pranke, N Servel, ...
Journal of Cystic Fibrosis 21, S376-S377, 2022
2022
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