Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR N Baatallah, A Elbahnsi, JP Mornon, B Chevalier, I Pranke, N Servel, ... Cellular and Molecular Life Sciences 78, 7813-7829, 2021 | 44 | 2021 |
Combining theoretical and experimental data to decipher CFTR 3D structures and functions B Hoffmann, A Elbahnsi, P Lehn, JL Décout, F Pietrucci, JP Mornon, ... Cellular and molecular life sciences 75, 3829-3855, 2018 | 25 | 2018 |
Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium A Mehregan, S Pérez-Conesa, Y Zhuang, A Elbahnsi, D Pasini, E Lindahl, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1864 (10), 183994, 2022 | 21* | 2022 |
Holding the nucleosome together: a quantitative description of the DNA–histone interface in solution A Elbahnsi, R Retureau, M Baaden, B Hartmann, C Oguey Journal of chemical theory and computation 14 (2), 1045-1058, 2018 | 21 | 2018 |
Simulations meet experiment to reveal new insights into DNA intrinsic mechanics A Ben Imeddourene, A Elbahnsi, M Guéroult, C Oguey, N Foloppe, ... PLoS Computational Biology 11 (12), e1004631, 2015 | 21 | 2015 |
Molecular model of the ferroportin intracellular gate and implications for the human iron transport cycle and hemochromatosis type 4A J Guellec, A Elbahnsi, ML Tertre, K Uguen, I Gourlaouen, C Férec, C Ka, ... The FASEB Journal 33 (12), 14625-14635, 2019 | 17 | 2019 |
Structural explorations of NCp7–nucleic acid complexes give keys to decipher the binding process R Retureau, C Oguey, O Mauffret, B Hartmann Journal of molecular biology 431 (10), 1966-1980, 2019 | 17 | 2019 |
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity L Froux, A Elbahnsi, B Boucherle, A Billet, N Baatallah, B Hoffmann, ... European Journal of Medicinal Chemistry 190, 112116, 2020 | 15 | 2020 |
High-resolution biophysical analysis of the dynamics of nucleosome formation A Hatakeyama, B Hartmann, A Travers, C Nogues, M Buckle Scientific reports 6 (1), 27337, 2016 | 14 | 2016 |
New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation S Bitam, A Elbahnsi, G Creste, I Pranke, B Chevalier, F Berhal, ... Scientific reports 11 (1), 6842, 2021 | 9 | 2021 |
Functional and pharmacological characterization of the rare CFTR mutation W361R A Billet, A Elbahnsi, M Jollivet-Souchet, B Hoffmann, JP Mornon, ... Frontiers in Pharmacology 11, 295, 2020 | 9 | 2020 |
Structure and sequence-based computational approaches to allosteric signal transduction: application to electromechanical coupling in voltage-gated ion channels A Elbahnsi, L Delemotte Journal of Molecular Biology 433 (17), 167095, 2021 | 5 | 2021 |
A dynamic view of DNA structure within the nucleosome: Biological implications R Retureau, N Foloppe, A Elbahnsi, C Oguey, B Hartmann Journal of structural biology 211 (1), 107511, 2020 | 4 | 2020 |
Interplay between VSD, pore, and membrane lipids in electromechanical coupling in HCN channels A Elbahnsi, J Cowgill, V Burtscher, L Wedemann, L Zeckey, B Chanda, ... Elife 12, e80303, 2023 | 3 | 2023 |
Insights into the Role of the Discontinuous TM7 Helix of Human Ferroportin through the Prism of the Asp325 Residue M Le Tertre, A Elbahnsi, C Ka, I Callebaut, G Le Gac International Journal of Molecular Sciences 22 (12), 6412, 2021 | 2 | 2021 |
Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases JL Delaunay, A Elbahnsi, A Bruneau, C Madry, AM Durand-Schneider, ... International Journal of Molecular Sciences 24 (2), 1236, 2023 | 1 | 2023 |
Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants N Baatallah, A Elbahnsi, B Chevalier, S Castanier, JP Mornon, I Pranke, ... International Journal of Molecular Sciences 23 (24), 16225, 2022 | 1 | 2022 |
CFTR corrector efficacy is associated with occupancy of distinct binding sites N Baatallah, A Elbahnsi, JP Mornon, B Chevalier, I Pranke, N Servel, ... bioRxiv, 2021.05. 04.442442, 2021 | 1 | 2021 |
Insights into the role of glycerophospholipids on the iron export function of SLC40A1 and the molecular mechanisms of ferroportin disease. R Debbiche, A Elbahnsi, K Uguen, C Ka, I Callebaut, G Le Gac bioRxiv, 2024.02. 05.578958, 2024 | | 2024 |
689 Pharmacological chaperones improve intradomain stability and interdomain assembly via distinct binding sites to rescue misfolded cystic fibrosis transmembrane conductance … N Baatallah, A Elbahnsi, J Mornon, B Chevalier, I Pranke, N Servel, ... Journal of Cystic Fibrosis 21, S376-S377, 2022 | | 2022 |