フォロー
Kadoaki Ohashi
Kadoaki Ohashi
Okayama University Hospital, Associate Professor
確認したメール アドレス: s.okayama-u.ac.jp
タイトル
引用先
引用先
HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFR T790M mutation
K Takezawa, V Pirazzoli, ME Arcila, CA Nebhan, X Song, E de Stanchina, ...
Cancer discovery 2 (10), 922-933, 2012
7442012
Capmatinib in MET Exon 14–Mutated or MET-Amplified Non–Small-Cell Lung Cancer
J Wolf, T Seto, JY Han, N Reguart, EB Garon, HJM Groen, DSW Tan, ...
New England Journal of Medicine 383 (10), 944-957, 2020
7012020
Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC
AO Walter, RTT Sjin, HJ Haringsma, K Ohashi, J Sun, K Lee, ...
Cancer discovery 3 (12), 1404-1415, 2013
7012013
Efficacy of Selpercatinib in RET Fusion–Positive Non–Small-Cell Lung Cancer
A Drilon, GR Oxnard, DSW Tan, HHF Loong, M Johnson, J Gainor, ...
New England Journal of Medicine 383 (9), 813-824, 2020
6662020
Optimization of dosing for EGFR-mutant non–small cell lung cancer with evolutionary cancer modeling
J Chmielecki, J Foo, GR Oxnard, K Hutchinson, K Ohashi, R Somwar, ...
Science translational medicine 3 (90), 90ra59-90ra59, 2011
5892011
Epidermal growth factor receptor tyrosine kinase inhibitor–resistant disease
K Ohashi, YE Maruvka, F Michor, W Pao
Journal of Clinical Oncology 31 (8), 1070, 2013
5232013
Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1
K Ohashi, LV Sequist, ME Arcila, T Moran, J Chmielecki, YL Lin, Y Pan, ...
Proceedings of the National Academy of Sciences 109 (31), E2127-E2133, 2012
5092012
Characteristics of Lung Cancers Harboring NRAS Mutations
K Ohashi, LV Sequist, ME Arcila, CM Lovly, X Chen, CM Rudin, T Moran, ...
Clinical Cancer Research 19 (9), 2584-2591, 2013
1742013
Tumour-agnostic efficacy and safety of selpercatinib in patients with RET fusion-positive solid tumours other than lung or thyroid tumours (LIBRETTO-001): a phase 1/2, open …
V Subbiah, J Wolf, B Konda, H Kang, A Spira, J Weiss, M Takeda, Y Ohe, ...
The Lancet Oncology 23 (10), 1261-1273, 2022
1672022
A phase II study of trastuzumab emtansine in HER2-positive non–small cell lung cancer
K Hotta, K Aoe, T Kozuki, K Ohashi, K Ninomiya, E Ichihara, T Kubo, ...
Journal of Thoracic Oncology 13 (2), 273-279, 2018
1412018
Non–small cell lung cancer cells acquire resistance to the ALK inhibitor alectinib by activating alternative receptor tyrosine kinases
H Isozaki, E Ichihara, N Takigawa, K Ohashi, N Ochi, M Yasugi, ...
Cancer research 76 (6), 1506-1516, 2016
1382016
PL02. 08 registrational results of LIBRETTO-001: a phase 1/2 trial of LOXO-292 in patients with RET fusion-positive lung cancers
A Drilon, G Oxnard, L Wirth, B Besse, O Gautschi, SWD Tan, H Loong, ...
Journal of Thoracic Oncology 14 (10), S6-S7, 2019
1022019
Double mutation and gene copy number of EGFR in gefitinib refractory non-small-cell lung cancer
M Tokumo, S Toyooka, S Ichihara, K Ohashi, K Tsukuda, K Ichimura, ...
Lung cancer 53 (1), 117-121, 2006
742006
Effects of vandetanib on lung adenocarcinoma cells harboring epidermal growth factor receptor T790M mutation in vivo
E Ichihara, K Ohashi, N Takigawa, M Osawa, A Ogino, M Tanimoto, ...
Cancer research 69 (12), 5091-5098, 2009
712009
Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and-resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with …
P Jia, H Jin, CB Meador, J Xia, K Ohashi, L Liu, V Pirazzoli, KB Dahlman, ...
Genome research 23 (9), 1434-1445, 2013
652013
The effect and safety of immune checkpoint inhibitor rechallenge in non-small cell lung cancer
H Watanabe, T Kubo, K Ninomiya, K Kudo, D Minami, E Murakami, N Ochi, ...
Japanese journal of clinical oncology 49 (8), 762-765, 2019
542019
JAK 2‐related pathway induces acquired erlotinib resistance in lung cancer cells harboring an epidermal growth factor receptor‐activating mutation
D Harada, N Takigawa, N Ochi, T Ninomiya, M Yasugi, T Kubo, H Takeda, ...
Cancer science 103 (10), 1795-1802, 2012
532012
NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor
E Galvani, J Sun, LG Leon, R Sciarrillo, RS Narayan, RTT Sjin, K Lee, ...
Oncotarget 6 (40), 42717, 2015
462015
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I
J Brägelmann, C Lorenz, S Borchmann, K Nishii, J Wegner, L Meder, ...
Nature communications 12 (1), 5505, 2021
382021
MET or NRAS amplification is an acquired resistance mechanism to the third-generation EGFR inhibitor naquotinib
K Ninomiya, K Ohashi, G Makimoto, S Tomida, H Higo, H Kayatani, ...
Scientific reports 8 (1), 1955, 2018
372018
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