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Urmi Sengupta
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The role of amyloid-β oligomers in toxicity, propagation, and immunotherapy
U Sengupta, AN Nilson, R Kayed
EBioMedicine 6, 42-49, 2016
7202016
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, AL Clos, ...
Molecular neurodegeneration 6, 1-14, 2011
6082011
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, J Sarmiento, ...
The FASEB Journal 26 (5), 1946, 2012
5482012
Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, ...
Scientific reports 2 (1), 700, 2012
5382012
Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles
DL Castillo-Carranza, U Sengupta, MJ Guerrero-Muñoz, ...
Journal of Neuroscience 34 (12), 4260-4272, 2014
3002014
Specific targeting of tau oligomers in htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds
DL Castillo-Carranza, JE Gerson, U Sengupta, MJ Guerrero-Muñoz, ...
Journal of Alzheimer's Disease 40 (s1), S97-S111, 2014
1862014
Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies
U Sengupta, MJ Guerrero-Muñoz, DL Castillo-Carranza, ...
Biological psychiatry 78 (10), 672-683, 2015
1782015
Tau oligomers associate with inflammation in the brain and retina of tauopathy mice and in neurodegenerative diseases
AN Nilson, KC English, JE Gerson, T Barton Whittle, C Nicolas Crain, ...
Journal of Alzheimer's Disease 55 (3), 1083-1099, 2017
1642017
Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies
BE Hawkins, S Krishnamurthy, DL Castillo-Carranza, U Sengupta, ...
Journal of Biological Chemistry 288 (23), 17042-17050, 2013
1612013
Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model
DL Castillo-Carranza, MJ Guerrero-Muñoz, U Sengupta, C Hernandez, ...
Journal of Neuroscience 35 (12), 4857-4868, 2015
1532015
Soluble tau aggregates, not large fibrils, are the toxic species that display seeding and cross‐seeding behavior
G Ghag, N Bhatt, DV Cantu, MJ Guerrero‐Munoz, A Ellsworth, ...
Protein Science 27 (11), 1901-1909, 2018
1082018
Tau oligomers derived from traumatic brain injury cause cognitive impairment and accelerate onset of pathology in Htau mice
J Gerson, DL Castillo-Carranza, U Sengupta, R Bodani, DS Prough, ...
Journal of neurotrauma 33 (22), 2034-2043, 2016
1022016
TDP-43 Phosphorylation by casein kinase Iε promotes oligomerization and enhances toxicity in vivo
DK Choksi, B Roy, S Chatterjee, T Yusuff, MF Bakhoum, U Sengupta, ...
Human molecular genetics 23 (4), 1025-1035, 2014
1022014
Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases
U Sengupta, R Kayed
Progress in Neurobiology 214, 102270, 2022
1012022
Cerebral microvascular accumulation of tau oligomers in Alzheimer’s disease and related tauopathies
DL Castillo-Carranza, AN Nilson, CE Van Skike, JB Jahrling, K Patel, ...
Aging and disease 8 (3), 257, 2017
1002017
Characterization of tau oligomeric seeds in progressive supranuclear palsy
JE Gerson, U Sengupta, CA Lasagna-Reeves, MJ Guerrero-Muñoz, ...
Acta neuropathologica communications 2, 1-9, 2014
1002014
Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia
S Gaikwad, N Puangmalai, A Bittar, M Montalbano, S Garcia, S McAllen, ...
Cell reports 36 (3), 2021
992021
Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity
CA Lasagna-Reeves, AL Clos, D Castillo-Carranza, U Sengupta, ...
Biochemical and biophysical research communications 430 (3), 963-968, 2013
982013
Tau oligomers in cerebrospinal fluid in Alzheimer's disease
U Sengupta, E Portelius, O Hansson, K Farmer, D Castillo‐Carranza, ...
Annals of clinical and translational neurology 4 (4), 226-235, 2017
882017
α-Synuclein oligomers induce a unique toxic tau strain
DL Castillo-Carranza, MJ Guerrero-Muñoz, U Sengupta, JE Gerson, ...
Biological psychiatry 84 (7), 499-508, 2018
842018
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