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David Robert McIlwain
David Robert McIlwain
Sonstige NamenDavid McIlwain
Bestätigte E-Mail-Adresse bei unr.edu
Titel
Zitiert von
Zitiert von
Jahr
Caspase functions in cell death and disease
DR McIlwain, T Berger, TW Mak
Cold Spring Harbor perspectives in biology 5 (4), a008656, 2013
29872013
Coordinated cellular neighborhoods orchestrate antitumoral immunity at the colorectal cancer invasive front
CM Schürch, SS Bhate, GL Barlow, DJ Phillips, L Noti, I Zlobec, P Chu, ...
Cell 182 (5), 1341-1359. e19, 2020
5722020
An immune clock of human pregnancy
N Aghaeepour, EA Ganio, D Mcilwain, AS Tsai, M Tingle, S Van Gassen, ...
Science immunology 2 (15), eaan2946, 2017
4382017
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
DR McIlwain, PA Lang, T Maretzky, K Hamada, K Ohishi, SK Maney, ...
Science 335 (6065), 229-232, 2012
3652012
ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
IT Lee, T Nakayama, CT Wu, Y Goltsev, S Jiang, PA Gall, CK Liao, ...
Nature communications 11 (1), 5453, 2020
2322020
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis
PDA Issuree, T Maretzky, DR McIlwain, S Monette, X Qing, PA Lang, ...
The Journal of clinical investigation 123 (2), 928-932, 2013
1932013
Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay
DR McIlwain, Q Pan, PT Reilly, AJ Elia, S McCracken, AC Wakeham, ...
Proceedings of the National Academy of Sciences 107 (27), 12186-12191, 2010
1892010
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding
T Maretzky, DR McIlwain, PDA Issuree, X Li, J Malapeira, S Amin, ...
Proceedings of the National Academy of Sciences 110 (28), 11433-11438, 2013
1802013
iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling
X Li, T Maretzky, G Weskamp, S Monette, X Qing, PDA Issuree, ...
Proceedings of the National Academy of Sciences 112 (19), 6080-6085, 2015
1572015
Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy
MS Ghaemi, DB DiGiulio, K Contrepois, B Callahan, TTM Ngo, ...
Bioinformatics 35 (1), 95-103, 2019
1502019
A comprehensive atlas of immunological differences between humans, mice, and non-human primates
ZB Bjornson-Hooper, GK Fragiadakis, MH Spitzer, H Chen, D Madhireddy, ...
Frontiers in immunology 13, 867015, 2022
922022
Efficacy, immunogenicity, and safety of an oral influenza vaccine: a placebo-controlled and active-controlled phase 2 human challenge study
D Liebowitz, K Gottlieb, NS Kolhatkar, SJ Garg, JM Asher, J Nazareno, ...
The Lancet Infectious Diseases 20 (4), 435-444, 2020
872020
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling
X Qing, Y Chinenov, P Redecha, M Madaio, JJTH Roelofs, G Farber, ...
The Journal of clinical investigation 128 (4), 1397-1412, 2018
862018
IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV
M Grusdat, DR McIlwain, HC Xu, VI Pozdeev, J Knievel, SQ Crome, ...
Cell Death & Differentiation 21 (7), 1050-1060, 2014
842014
Involvement of Toso in activation of monocytes, macrophages, and granulocytes
KS Lang, PA Lang, A Meryk, AA Pandyra, LM Boucher, VI Pozdeev, ...
Proceedings of the National Academy of Sciences 110 (7), 2593-2598, 2013
802013
Single-cell profiling of Ebola virus disease in vivo reveals viral and host dynamics
D Kotliar, AE Lin, J Logue, TK Hughes, NM Khoury, SS Raju, ...
Cell 183 (5), 1383-1401. e19, 2020
792020
Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17
SK Maney, DR McIlwain, R Polz, AA Pandyra, B Sundaram, D Wolff, ...
Science Signaling 8 (401), ra109, 2015
662015
Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments
S Jiang, CN Chan, X Rovira-Clavé, H Chen, Y Bai, B Zhu, E McCaffrey, ...
Immunity 55 (6), 1118-1134. e8, 2022
58*2022
Integration of mechanistic immunological knowledge into a machine learning pipeline improves predictions
A Culos, AS Tsai, N Stanley, M Becker, MS Ghaemi, DR McIlwain, ...
Nature machine intelligence 2 (10), 619-628, 2020
532020
Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway
C Haxaire, N Hakobyan, T Pannellini, C Carballo, D McIlwain, TW Mak, ...
Blood, The Journal of the American Society of Hematology 132 (10), 1064-1074, 2018
492018
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