The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry TP Peacock, JC Brown, J Zhou, N Thakur, J Newman, R Kugathasan, ... BioRxiv 10 (2021.12), 31.474653, 2022 | 243 | 2022 |
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses TK Tan, P Rijal, R Rahikainen, AH Keeble, L Schimanski, S Hussain, ... Nature communications 12 (1), 542, 2021 | 230 | 2021 |
Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19 SP Graham, RK McLean, AJ Spencer, S Belij-Rammerstorfer, D Wright, ... NPJ vaccines 5 (1), 69, 2020 | 149 | 2020 |
Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2 J Newman, N Thakur, TP Peacock, D Bialy, AME Elrefaey, C Bogaardt, ... Nature microbiology 7 (8), 1180-1188, 2022 | 50 | 2022 |
The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B. 1.351) and other variants of concern in preclinical studies AJ Spencer, S Morris, M Ulaszewska, C Powers, R Kailath, C Bissett, ... EBioMedicine 77, 2022 | 29 | 2022 |
The cellular chaperone heat shock protein 90 is required for foot-and-mouth disease virus capsid precursor processing and assembly of capsid pentamers J Newman, AS Asfor, S Berryman, T Jackson, S Curry, TJ Tuthill Journal of virology 92 (5), 10.1128/jvi. 01415-17, 2018 | 27 | 2018 |
Deep sequencing of foot-and-mouth disease virus reveals RNA sequences involved in genome packaging G Logan, J Newman, CF Wright, L Lasecka-Dykes, DT Haydon, ... Journal of virology 92 (1), 10.1128/jvi. 01159-17, 2018 | 25 | 2018 |
SARS-CoV-2 variants of concern alpha, beta, gamma and delta have extended ACE2 receptor host ranges N Thakur, G Gallo, J Newman, TP Peacock, L Biasetti, CN Hall, E Wright, ... Journal of General Virology 103 (4), 001735, 2022 | 24 | 2022 |
ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants N van Doremalen, JE Schulz, DR Adney, TA Saturday, RJ Fischer, ... Nature communications 13 (1), 4610, 2022 | 22 | 2022 |
Cleavages at the three junctions within the foot-and-mouth disease virus capsid precursor (P1–2A) by the 3C protease are mutually independent T Kristensen, J Newman, SH Guan, TJ Tuthill, GJ Belsham Virology 522, 260-270, 2018 | 19 | 2018 |
Distinct antigenic properties of the SARS-CoV-2 Omicron lineages BA. 4 and BA. 5 BJ Willett, A Kurshan, N Thakur, J Newman, M Manali, G Tyson, N Logan, ... bioRxiv, 2022.05. 25.493397, 2022 | 17 | 2022 |
Neutralising antibody activity against SARS-CoV-2 variants, including Omicron, in an elderly cohort vaccinated with BNT162b2 J Newman, N Thakur, TP Peacock, D Bialy, AME Elreafey, C Bogaardt, ... medRxiv, 2021.12. 23.21268293, 2021 | 16 | 2021 |
Porcine respiratory coronavirus as a model for acute respiratory coronavirus disease S Keep, BV Carr, FZX Lean, A Fones, J Newman, G Dowgier, G Freimanis, ... Frontiers in immunology 13, 867707, 2022 | 14 | 2022 |
Efficacy of ChAdOx1 vaccines against SARS-CoV-2 Variants of Concern Beta, Delta and Omicron in the Syrian hamster model N van Doremalen, JE Schulz, DR Adney, TA Saturday, RJ Fischer, ... Research Square, 2022 | 11 | 2022 |
Generation of antibodies against foot-and-mouth-disease virus capsid protein VP4 using hepatitis B core VLPs as a scaffold J Swanson, R Fragkoudis, PC Hawes, J Newman, A Burman, A Panjwani, ... Life 11 (4), 338, 2021 | 7 | 2021 |
Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients D Cantoni, M Mayora-Neto, N Thakur, AME Elrefaey, J Newman, ... Communications Biology 5 (1), 409, 2022 | 6 | 2022 |
An engineered maturation cleavage provides a recombinant mimic of foot-and-mouth disease virus capsid assembly-disassembly J Newman, DJ Rowlands, TJ Tuthill Life 11 (6), 500, 2021 | 6 | 2021 |
Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays G Shimmon, A Kotecha, J Ren, AS Asfor, J Newman, S Berryman, ... Plos one 13 (8), e0201853, 2018 | 4 | 2018 |
Membrane interactions and uncoating of Aichi virus, a picornavirus that lacks a VP4 JT Kelly, J Swanson, J Newman, E Groppelli, NJ Stonehouse, TJ Tuthill Journal of Virology 96 (7), e00082-22, 2022 | 3 | 2022 |
An ACAT inhibitor regulates SARS-CoV-2 replication and antiviral T cell activity NM Schmidt, PAC Wing, R Peters, R Brown, H Wang, L Swadling, ... BioRxiv, 2022.04. 12.487988, 2022 | 2 | 2022 |