Bone marrow–specific deficiency of nuclear receptor Nur77 enhances atherosclerosis AAJ Hamers, M Vos, F Rassam, G Marinković, K Kurakula, PJ Van Gorp, ... Circulation research 110 (3), 428-438, 2012 | 180 | 2012 |
NR4A nuclear receptors are orphans but not lonesome K Kurakula, DS Koenis, CM van Tiel, CJM de Vries Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (11), 2543-2555, 2014 | 150 | 2014 |
Cardiac endothelial cells express Wilms' tumor-1: Wt1 expression in the developing, adult and infarcted heart SN Duim, K Kurakula, MJ Goumans, BPT Kruithof Journal of molecular and cellular cardiology 81, 127-135, 2015 | 118 | 2015 |
Multicenter preclinical validation of BET inhibition for the treatment of pulmonary arterial hypertension DE Van der Feen, K Kurakula, E Tremblay, O Boucherat, GPL Bossers, ... American journal of respiratory and critical care medicine 200 (7), 910-920, 2019 | 110 | 2019 |
TGF-β and BMPR2 signaling in PAH: two black sheep in one family N Rol, KB Kurakula, C Happé, HJ Bogaard, MJ Goumans International journal of molecular sciences 19 (9), 2585, 2018 | 106 | 2018 |
Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension D da Silva Gonçalves Bós, CEE Van Der Bruggen, K Kurakula, XQ Sun, ... Circulation 137 (9), 910-924, 2018 | 102 | 2018 |
Endothelial dysfunction in pulmonary hypertension: cause or consequence? K Kurakula, VFED Smolders, O Tura-Ceide, JW Jukema, PHA Quax, ... Biomedicines 9 (1), 57, 2021 | 82 | 2021 |
Cellular senescence impairs the reversibility of pulmonary arterial hypertension DE Van Der Feen, GPL Bossers, QAJ Hagdorn, JR Moonen, K Kurakula, ... Science Translational Medicine 12 (554), eaaw4974, 2020 | 80 | 2020 |
Protein–protein interactions of the LIM-only protein FHL2 and functional implication of the interactions relevant in cardiovascular disease MK Tran, K Kurakula, DS Koenis, CJM de Vries Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (2), 219-228, 2016 | 71 | 2016 |
Nuclear receptor Nur77 attenuates airway inflammation in mice by suppressing NF-κB activity in lung epithelial cells K Kurakula, M Vos, A Logiantara, JJ Roelofs, MA Nieuwenhuis, ... The Journal of Immunology 195 (4), 1388-1398, 2015 | 63 | 2015 |
Nuclear receptor Nur77 attenuates airway inflammation in mice by suppressing NF-κB activity in lung epithelial cells K Kurakula, M Vos, A Logiantara, JJ Roelofs, MA Nieuwenhuis, ... The Journal of Immunology 195 (4), 1388-1398, 2015 | 63 | 2015 |
Inhibition of GTPase Rac1 in endothelium by 6-mercaptopurine results in immunosuppression in nonimmune cells: new target for an old drug G Marinković, J Kroon, M Hoogenboezem, KA Hoeben, MS Ruiter, ... The Journal of Immunology 192 (9), 4370-4378, 2014 | 57 | 2014 |
FHL2 protein is a novel co-repressor of nuclear receptor Nur77 K Kurakula, E Van Der Wal, D Geerts, CM Van Tiel, CJM De Vries Journal of Biological Chemistry 286 (52), 44336-44343, 2011 | 55 | 2011 |
Thoracic aortic aneurysm development in patients with bicuspid aortic valve: what is the role of endothelial cells? V Van de Pol, K Kurakula, MC DeRuiter, MJ Goumans Frontiers in physiology 8, 289792, 2017 | 45 | 2017 |
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension N Rol, MA de Raaf, XQ Sun, VP Kuiper, D da Silva Gonçalves Bos, ... Cardiovascular research 115 (2), 432-439, 2019 | 40 | 2019 |
Endothelial dysfunction in pulmonary arterial hypertension: loss of cilia length regulation upon cytokine stimulation A Dummer, N Rol, R Szulcek, K Kurakula, X Pan, BI Visser, HJ Bogaard, ... Pulmonary circulation 8 (2), 2045894018764629, 2018 | 38 | 2018 |
Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension MC Gomez‐Puerto, I van Zuijen, CJZ Huang, R Szulcek, X Pan, ... The Journal of pathology 249 (3), 356-367, 2019 | 36 | 2019 |
The BMP receptor 2 in pulmonary arterial hypertension: when and where the animal model matches the patient C Happé, K Kurakula, XQ Sun, D da Silva Goncalves Bos, N Rol, ... Cells 9 (6), 1422, 2020 | 35 | 2020 |
6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFκB activation in airway epithelial cells K Kurakula, AA Hamers, P van Loenen, CJM de Vries Respiratory research 16, 1-9, 2015 | 35 | 2015 |
Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling K Kurakula, XQ Sun, C Happé, DSG Bos, R Szulcek, I Schalij, ... European Respiratory Journal 54 (3), 2019 | 29 | 2019 |