| Chemically induced degradation of sirtuin 2 (Sirt2) by a proteolysis targeting chimera (PROTAC) based on sirtuin rearranging ligands (SirReals) M Schiedel, D Herp, S Hammelmann, S Swyter, A Lehotzky, D Robaa, ... Journal of medicinal chemistry 61 (2), 482-491, 2018 | 271 | 2018 |
| Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis T Heimburg, A Chakrabarti, J Lancelot, M Marek, J Melesina, AT Hauser, ... Journal of Medicinal Chemistry 59 (6), 2423-2435, 2016 | 132 | 2016 |
| The Current State of NAD+‐Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets M Schiedel, D Robaa, T Rumpf, W Sippl, M Jung Medicinal research reviews 38 (1), 147-200, 2018 | 128 | 2018 |
| Characterization of histone deacetylase 8 (HDAC8) selective inhibition reveals specific active site structural and functional determinants M Marek, TB Shaik, T Heimburg, A Chakrabarti, J Lancelot, ... Journal of medicinal chemistry 61 (22), 10000-10016, 2018 | 101 | 2018 |
| Synthesis and biological investigation of phenothiazine-based benzhydroxamic acids as selective histone deacetylase 6 inhibitors K Vögerl, N Ong, J Senger, D Herp, K Schmidtkunz, M Marek, M Müller, ... Journal of medicinal chemistry 62 (3), 1138-1166, 2019 | 92 | 2019 |
| Lysine deacetylase inhibitors in parasites: past, present, and future perspectives GS Hailu, D Robaa, M Forgione, W Sippl, D Rotili, A Mai Journal of Medicinal Chemistry 60 (12), 4780-4804, 2017 | 91 | 2017 |
| Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells E Plesch, CC Chen, E Butz, A Scotto Rosato, EK Krogsaeter, H Yinan, ... Elife 7, e39720, 2018 | 87 | 2018 |
| KATching-up on small molecule modulators of lysine acetyltransferases RP Simon, D Robaa, Z Alhalabi, W Sippl, M Jung Journal of medicinal chemistry 59 (4), 1249-1270, 2016 | 77 | 2016 |
| Structure-based design and biological characterization of selective histone deacetylase 8 (HDAC8) inhibitors with anti-neuroblastoma activity T Heimburg, FR Kolbinger, P Zeyen, E Ghazy, D Herp, K Schmidtkunz, ... Journal of Medicinal Chemistry 60 (24), 10188-10204, 2017 | 75 | 2017 |
| Strategies to design selective histone deacetylase inhibitors J Melesina, CV Simoben, L Praetorius, EF Bülbül, D Robaa, W Sippl ChemMedChem 16 (9), 1336-1359, 2021 | 67 | 2021 |
| Mind the methyl: methyllysine binding proteins in epigenetic regulation T Wagner, D Robaa, W Sippl, M Jung ChemMedChem 9 (3), 466-483, 2014 | 52 | 2014 |
| Proteolysis targeting chimeras (PROTACs) for epigenetics research A Vogelmann, D Robaa, W Sippl, M Jung Current opinion in chemical biology 57, 8-16, 2020 | 49 | 2020 |
| Homology modeling of parasite histone deacetylases to guide the structure-based design of selective inhibitors J Melesina, D Robaa, RJ Pierce, C Romier, W Sippl Journal of Molecular Graphics and Modelling 62, 342-361, 2015 | 49 | 2015 |
| Epigenetic small molecule modulators of histone and DNA methylation AT Hauser, D Robaa, M Jung Current Opinion in Chemical Biology 45, 73-85, 2018 | 46 | 2018 |
| A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing CV Simoben, D Robaa, A Chakrabarti, K Schmidtkunz, M Marek, ... Molecules 23 (3), 566, 2018 | 45 | 2018 |
| Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic … J Schulz-Fincke, M Hau, J Barth, D Robaa, D Willmann, A Kürner, J Haas, ... European Journal of Medicinal Chemistry 144, 52-67, 2018 | 39 | 2018 |
| Muscle carnitine palmitoyltransferase II deficiency: a review of enzymatic controversy and clinical features D Lehmann, L Motlagh, D Robaa, S Zierz International Journal of Molecular Sciences 18 (1), 82, 2017 | 37 | 2017 |
| Enantiomerically Pure 2-Methyltetrahydro-3-benzazepin-1-ols Selectively Blocking GluN2B Subunit Containing N-Methyl-d-aspartate Receptors B Tewes, B Frehland, D Schepmann, D Robaa, T Uengwetwanit, F Gaube, ... Journal of Medicinal Chemistry 58 (15), 6293-6305, 2015 | 34 | 2015 |
| Identification and structure–activity relationship studies of small‐molecule inhibitors of the methyllysine reader protein Spindlin1 D Robaa, T Wagner, C Luise, L Carlino, J McMillan, R Flaig, R Schüle, ... ChemMedChem 11 (20), 2327-2338, 2016 | 32 | 2016 |
| Synthesis, molecular docking and biological characterization of pyrazine linked 2-aminobenzamides as new class I selective histone deacetylase (HDAC) inhibitors with anti … HS Ibrahim, M Abdelsalam, Y Zeyn, M Zessin, AHM Mustafa, MA Fischer, ... International Journal of Molecular Sciences 23 (1), 369, 2021 | 31 | 2021 |
