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Xuexiang Du
Xuexiang Du
University of Maryland School of Medicine
Verified email at ihv.umaryland.edu - Homepage
Title
Cited by
Cited by
Year
A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy
X Du, F Tang, M Liu, J Su, Y Zhang, W Wu, M Devenport, CA Lazarski, ...
Cell research 28 (4), 416-432, 2018
2332018
Intratumoral delivery of IL-21 overcomes anti-Her2/Neu resistance through shifting tumor-associated macrophages from M2 to M1 phenotype
M Xu, M Liu, X Du, S Li, H Li, X Li, Y Li, Y Wang, Z Qin, YX Fu, S Wang
The Journal of Immunology 194 (10), 4997-5006, 2015
1362015
Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice
X Du, M Liu, J Su, P Zhang, F Tang, P Ye, M Devenport, X Wang, Y Zhang, ...
Cell research 28 (4), 433-447, 2018
1082018
Anti-CTLA-4 antibodies in cancer immunotherapy: selective depletion of intratumoral regulatory T cells or checkpoint blockade?
F Tang, X Du, M Liu, P Zheng, Y Liu
Cell & Bioscience 8, 1-3, 2018
1062018
Preserving the CTLA-4 checkpoint for safer and more effective cancer immunotherapy
Y Liu, P Zheng
Trends in pharmacological sciences 41 (1), 4-12, 2020
1042020
The efficacy of oncolytic adenovirus is mediated by T-cell responses against virus and tumor in Syrian hamster model
X Li, P Wang, H Li, X Du, M Liu, Q Huang, Y Wang, S Wang
Clinical Cancer Research 23 (1), 239-249, 2017
892017
Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy
Y Zhang, X Du, M Liu, F Tang, P Zhang, C Ai, JK Fields, EJ Sundberg, ...
Cell Research 29 (8), 609-627, 2019
862019
Expression of the galectin-9‑Tim-3 pathway in glioma tissues is associated with the clinical manifestations of glioma
Z Liu, H Han, X He, S Li, C Wu, C Yu, S Wang
Oncology Letters 11 (3), 1829-1834, 2016
812016
How does an anti-CTLA-4 antibody promote cancer immunity?
Y Liu, P Zheng
Trends in immunology 39 (12), 953-956, 2018
722018
Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8+ T cell responses
L Cheng*, X Du*, Z Wang, J Ju, M Jia, Q Huang, Q Xing, M Xu, Y Tan, ...
Journal of hepatology 61 (6), 1297-1303, 2014
542014
Targeting HIF-1α abrogates PD-L1–mediated immune evasion in tumor microenvironment but promotes tolerance in normal tissues
CM Bailey, Y Liu, M Liu, X Du, M Devenport, P Zheng, Y Liu, Y Wang
The Journal of Clinical Investigation 132 (9), 2022
492022
CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder
X Wang, M Liu, J Zhang, NK Brown, P Zhang, Y Zhang, H Liu, X Du, W Wu, ...
Cell metabolism 34 (8), 1088-1103. e6, 2022
232022
The tumor immunosuppressive microenvironment impairs the therapy of anti-HER2/neu antibody
M Xu, X Du, M Liu, S Li, X Li, YX Fu, S Wang
Protein & cell 3, 441-449, 2012
152012
Mechanism-and immune landscape-based ranking of therapeutic responsiveness of 22 major human cancers to next generation anti-CTLA-4 antibodies
P Zhang, X Xiong, C Rolfo, X Du, Y Zhang, H Yang, A Russo, ...
Cancers 12 (2), 284, 2020
132020
CD24Fc ameliorates immune-related adverse events while preserving anti-tumor therapeutic effect
M Liu, X Wang, X Du, Y Zhang, C Ai, S Hu-Lieskovan, T Li, M Devenport, ...
Signal Transduction and Targeted Therapy 7 (1), 224, 2022
92022
S-15 in combination of Akt inhibitor promotes the expansion of CD45RACCR7+ tumor infiltrating lymphocytes with high cytotoxic potential and downregulating PD-1+Tim-3 …
B Xu, L Yuan, G Chen, T Li, J Zhou, C Zhang, P Qin, MM Muthana, ...
Cancer Cell International 19, 1-11, 2019
52019
Immunotherapy of metastatic and autochthonous liver cancer with IL-15/IL-15Rα fusion protein
L Cheng*, X Du*, L Su, S Wang
Oncoimmunology 3 (11), e963409, 2014
42014
Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4–and PD-1–targeted immunotherapy
M Liu, X Wang, X Du, W Wu, Y Zhang, P Zhang, C Ai, M Devenport, J Su, ...
Science translational medicine 15 (685), eabm5663, 2023
32023
Methods of selecting and designing safer and more effective anti-ctla-4 antibodies for cancer therapy
Y Liu, P Zheng, F Tang, LIU Mingyue, M Devenport, DU Xuexiang, ...
32019
CTLA-4 antibody-drug conjugate reveals autologous destruction of B-lymphocytes associated with regulatory T cell impairment
MM Muthana, X Du, M Liu, X Wang, W Wu, C Ai, L Su, P Zheng, Y Liu
Elife 12, RP87281, 2023
22023
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