Bacterial multidrug efflux pumps: much more than antibiotic resistance determinants P Blanco, S Hernando-Amado, JA Reales-Calderon, F Corona, F Lira, ... Microorganisms 4 (1), 14, 2016 | 702 | 2016 |
Multidrug efflux pumps at the crossroad between antibiotic resistance and bacterial virulence M Alcalde-Rico, S Hernando-Amado, P Blanco, JL Martínez Frontiers in microbiology 7, 215898, 2016 | 241 | 2016 |
Multidrug efflux pumps as main players in intrinsic and acquired resistance to antimicrobials S Hernando-Amado, P Blanco, M Alcalde-Rico, F Corona, ... Drug Resistance Updates 28, 13-27, 2016 | 187 | 2016 |
Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps J Olivares Pacheco, C Alvarez-Ortega, M Alcalde Rico, JL Martínez MBio 8 (4), 10.1128/mbio. 00500-17, 2017 | 86 | 2017 |
Role of the multidrug resistance efflux pump MexCD-OprJ in the Pseudomonas aeruginosa quorum sensing response M Alcalde-Rico, J Olivares-Pacheco, C Alvarez-Ortega, M Cámara, ... Frontiers in Microbiology 9, 415014, 2018 | 73 | 2018 |
The development of efflux pump inhibitors to treat Gram-negative infections P Blanco, F Sanz-García, S Hernando-Amado, JL Martínez, ... Expert opinion on drug discovery 13 (10), 919-931, 2018 | 49 | 2018 |
Naringenin inhibition of the Pseudomonas aeruginosa quorum sensing response is based on its time-dependent competition with N-(3-Oxo-dodecanoyl)-L-homoserine lactone for LasR … S Hernando-Amado, M Alcalde-Rico, T Gil-Gil, JR Valverde, JL Martínez Frontiers in molecular biosciences 7, 25, 2020 | 47 | 2020 |
The impaired quorum sensing response of Pseudomonas aeruginosa MexABOprM efflux pump overexpressing mutants is not due to nonphysiological efflux of 3 … M AlcaldeRico, J OlivaresPacheco, N Halliday, M Cámara, JL Martínez Environmental Microbiology 22 (12), 5167-5188, 2020 | 31 | 2020 |
Novel Inducers of the Expression of Multidrug Efflux Pumps That Trigger Pseudomonas aeruginosa Transient Antibiotic Resistance P Laborda, M Alcalde-Rico, P Blanco, JL Martínez, S Hernando-Amado Antimicrobial Agents and Chemotherapy 63 (11), 10.1128/aac. 01095-19, 2019 | 24 | 2019 |
The analysis of the antibiotic resistome offers new opportunities for therapeutic intervention F Corona, P Blanco, M Alcalde-Rico, S Hernando-Amado, F Lira, ... Future medicinal chemistry 8 (10), 1133-1151, 2016 | 19 | 2016 |
Discovery of inhibitors of Pseudomonas aeruginosa virulence through the search for naturallike compounds with a dual role as inducers and substrates of efflux … P Laborda, M AlcaldeRico, A Chini, JL Martínez, S HernandoAmado Environmental Microbiology 23 (12), 7396-7411, 2021 | 16 | 2021 |
Genetic characterization of clinically relevant class 1 integrons carried by multidrug resistant bacteria (MDRB) isolated from the gut microbiota of highly antibiotic treated … F Vásquez-Ponce, S Higuera-Llantén, J Parás-Silva, N Gamboa-Acuña, ... Journal of Global Antimicrobial Resistance 29, 55-62, 2022 | 8 | 2022 |
The MexJK Multidrug Efflux Pump Is Not Involved in Acquired or Intrinsic Antibiotic Resistance in Pseudomonas aeruginosa, but Modulates the Bacterial Quorum … R Amieva, T Gil-Gil, JL Martínez, M Alcalde-Rico International Journal of Molecular Sciences 23 (14), 7492, 2022 | 7 | 2022 |
Methods for measuring the production of quorum sensing signal molecules M Alcalde-Rico, JL Martínez Antibiotic Resistance Protocols, 1-15, 2018 | 6 | 2018 |
Use of phenotype microarrays to study the effect of acquisition of resistance to antimicrobials in bacterial physiology JA Reales-Calderon, P Blanco, M Alcalde-Rico, F Corona, F Lira, ... Research in microbiology 167 (9-10), 723-730, 2016 | 5 | 2016 |
Acquisition of resistance to ceftazidime-avibactam during infection treatment in Pseudomonas aeruginosa through D179Y mutation in one of two blaKPC-2 gene … P García, B Brito, M Alcalde-Rico, JM Munita, JRW Martínez, ... Frontiers in Cellular and Infection Microbiology 12, 981792, 2022 | 3 | 2022 |
Dynamics of the MRSA Population in a Chilean Hospital: a Phylogenomic Analysis (2000–2016) JRW Martínez, PJ Planet, M Spencer-Sandino, L Rivas, L Díaz, ... Microbiology Spectrum 11 (4), e05351-22, 2023 | 2 | 2023 |
Isolation of an Extensively Drug-Resistant Pseudomonas aeruginosa exoS+/O4 Strain Belonging to the “High-Risk” Clone ST654 and Coproducer of NDM-1 and … A Opazo-Capurro, F Morales-León, C Jerez, J Olivares-Pacheco, ... Microbiology Spectrum 10 (5), e01439-22, 2022 | 2 | 2022 |
Role of the multi-drug efflux systems on the baseline susceptibility to ceftazidime/avibactam and ceftolozane/tazobactam in clinical isolates of non-carbapenemase-producing … MJ Contreras-Gómez, JRW Martinez, L Rivas, R Riquelme-Neira, ... Frontiers in Pharmacology 13, 1007162, 2022 | 2 | 2022 |
Real-world performance of susceptibility testing for ceftolozane/tazobactam against non-carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa L Rivas, M Alcalde-Rico, JRW Martínez, MV Moreno, P Rojas, A Wozniak, ... Antimicrobial Agents and Chemotherapy 66 (1), e01657-21, 2022 | 2 | 2022 |