| CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity BD Choi, X Yu, AP Castano, AA Bouffard, A Schmidts, RC Larson, ... Nature Biotechnology 37 (9), 1049-1058, 2019 | 408 | 2019 |
| Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells NR Mathew, F Baumgartner, L Braun, D O'Sullivan, S Thomas, ... Nature Medicine 24 (3), 282-291, 2018 | 254 | 2018 |
| CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma BD Choi, X Yu, AP Castano, H Darr, DB Henderson, AA Bouffard, ... Journal for ImmunoTherapy of Cancer 7 (1), 1-8, 2019 | 241 | 2019 |
| CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours RC Larson, MC Kann, SR Bailey, NJ Haradhvala, PM Llopis, AA Bouffard, ... Nature 604 (7906), 563-570, 2022 | 179 | 2022 |
| Making CAR T cells a solid option for solid tumors A Schmidts, MV Maus Frontiers in Immunology 9, 2593, 2018 | 174 | 2018 |
| Reversible ON-and OFF-switch chimeric antigen receptors controlled by lenalidomide M Jan, I Scarfò, RC Larson, A Walker, A Schmidts, AA Guirguis, JA Gasser, ... Science Translational Medicine 13 (575), eabb6295, 2021 | 158 | 2021 |
| CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells K Petri*, W Zhang*, J Ma*, A Schmidts*, H Lee, JE Horng, DY Kim, IC Kurt, ... Nature Biotechnology, 1-5, 2021 | 141 | 2021 |
| Cell cycle control in acute myeloid leukemia D Schnerch, J Yalcintepe, A Schmidts, H Becker, M Follo, M Engelhardt, ... American Journal of Cancer Research 2 (5), 508, 2012 | 97 | 2012 |
| Rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma A Schmidts, M Ormhøj, BD Choi, AO Taylor, AA Bouffard, I Scarfò, ... Blood Advances 3 (21), 3248-3260, 2019 | 96 | 2019 |
| Chimeric antigen receptor T cells targeting CD79b show efficacy in lymphoma with or without cotargeting CD19 M Ormhøj, I Scarfò, ML Cabral, SR Bailey, SJ Lorrey, AA Bouffard, ... Clinical Cancer Research 25 (23), 7046-7057, 2019 | 70 | 2019 |
| Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia MB Leick, H Silva, I Scarfò, R Larson, BD Choi, AA Bouffard, K Gallagher, ... Cancer cell 40 (5), 494-508. e5, 2022 | 62 | 2022 |
| Blockade or deletion of IFNγ reduces macrophage activation without compromising CAR T-cell function in hematologic malignancies SR Bailey, S Vatsa, RC Larson, AA Bouffard, I Scarfò, MC Kann, ... Blood Cancer Discovery 3 (2), 136-153, 2022 | 55 | 2022 |
| Toward better understanding and management of CAR-T cell–associated toxicity A Schmidts, M Wehrli, MV Maus Annual Review of Medicine 72, 365-382, 2021 | 44 | 2021 |
| BubR1 is frequently repressed in acute myeloid leukemia and its re-expression sensitizes cells to antimitotic therapy D Schnerch, A Schmidts, M Follo, J Udi, J Felthaus, D Pfeifer, ... Haematologica 98 (12), 1886, 2013 | 27 | 2013 |
| Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources A Schmidts, LC Marsh, AA Srivastava, AA Bouffard, AC Boroughs, I Scarfò, ... Journal for ImmunoTherapy of Cancer 8 (2), 2020 | 20 | 2020 |
| Dynamic profiling of antitumor activity of CAR T cells using micropatterned tumor arrays X Wang, I Scarfò, A Schmidts, M Toner, MV Maus, D Irimia Advanced Science 6 (23), 1901829, 2019 | 20 | 2019 |
| Tandem chimeric antigen receptor (CAR) T cells targeting EGFRvIII and IL-13Rα2 are effective against heterogeneous glioblastoma A Schmidts, AA Srivastava, R Ramapriyan, SR Bailey, AA Bouffard, ... Neuro-Oncology Advances 5 (1), vdac185, 2023 | 12 | 2023 |
| Suppression of APC/CCdh1 has subtype specific biological effects in acute myeloid leukemia D Ewerth, A Schmidts, M Hein, D Schnerch, A Kvainickas, C Greil, ... Oncotarget 7 (30), 48220, 2016 | 11 | 2016 |
| Use of CD70 targeted chimeric antigen receptor (CAR) T cells for the treatment of acute myeloid leukemia (AML) M Leick, I Scarfò, BD Choi, R Larson, AA Bouffard, A Castano, ML Cabral, ... Blood 134, 4443, 2019 | 6 | 2019 |
| APC/CCdh1 regulates the balance between maintenance and differentiation of hematopoietic stem and progenitor cells D Ewerth, S Kreutmair, A Schmidts, G Ihorst, M Follo, D Wider, J Felthaus, ... Cellular and molecular life sciences 76, 369-380, 2019 | 5 | 2019 |
Marcela V MausHarvard Medical SchoolVerified email at mgh.harvard.edu
