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Takashi Iezaki
Takashi Iezaki
Aichi Medical University
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Year
Glucose uptake and Runx2 synergize to orchestrate osteoblast differentiation and bone formation
J Wei, J Shimazu, MP Makinistoglu, A Maurizi, D Kajimura, H Zong, ...
Cell 161 (7), 1576-1591, 2015
4152015
Genetic analysis of Runx2 function during intramembranous ossification
T Takarada, R Nakazato, A Tsuchikane, K Fujikawa, T Iezaki, Y Yoneda, ...
Development 143 (2), 211-218, 2016
1082016
Bone resorption is regulated by circadian clock in osteoblasts
T Takarada, C Xu, H Ochi, R Nakazato, D Yamada, S Nakamura, ...
Journal of Bone and Mineral Research 32 (4), 872-881, 2017
1032017
Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia
E Hinoi, H Ochi, T Takarada, E Nakatani, T Iezaki, H Nakajima, H Fujita, ...
Journal of bone and mineral research 27 (4), 938-949, 2012
892012
The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice
T Yamamoto, E Hinoi, H Fujita, T Iezaki, Y Takahata, M Takamori, ...
British journal of pharmacology 166 (3), 1084-1096, 2012
832012
ATF3 deficiency in chondrocytes alleviates osteoarthritis development
T Iezaki, K Ozaki, K Fukasawa, M Inoue, S Kitajima, T Muneta, S Takeda, ...
The Journal of pathology 239 (4), 426-437, 2016
582016
Growth differentiation factor-5 promotes brown adipogenesis in systemic energy expenditure
E Hinoi, Y Nakamura, S Takada, H Fujita, T Iezaki, S Hashizume, ...
Diabetes 63 (1), 162-175, 2014
562014
PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway
E Hinoi, T Iezaki, H Fujita, T Watanabe, Y Odaka, K Ozaki, Y Yoneda
Biochemical and biophysical research communications 450 (1), 255-260, 2014
412014
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway
K Fukasawa, T Kadota, T Horie, K Tokumura, R Terada, Y Kitaguchi, ...
Oncogene 40 (15), 2803-2815, 2021
372021
ATF3 controls proliferation of osteoclast precursor and bone remodeling
K Fukasawa, G Park, T Iezaki, T Horie, T Kanayama, K Ozaki, Y Onishi, ...
Scientific reports 6 (1), 30918, 2016
372016
Repression of adipogenesis through promotion of Wnt/β-catenin signaling by TIS7 up-regulated in adipocytes under hypoxia
Y Nakamura, E Hinoi, T Iezaki, S Takada, S Hashizume, Y Takahata, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (8 …, 2013
372013
Daily intake of β-cryptoxanthin prevents bone loss by preferential disturbance of osteoclastic activation in ovariectomized mice
K Ozaki, M Okamoto, K Fukasawa, T Iezaki, Y Onishi, Y Yoneda, ...
Journal of Pharmacological Sciences 129 (1), 72-77, 2015
342015
Translational control of Sox9 RNA by mTORC1 contributes to skeletogenesis
T Iezaki, T Horie, K Fukasawa, M Kitabatake, Y Nakamura, G Park, ...
Stem Cell Reports 11 (1), 228-241, 2018
312018
The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway
K Ozaki, T Yamada, T Horie, A Ishizaki, M Hiraiwa, T Iezaki, G Park, ...
Science signaling 12 (589), eaaw3921, 2019
292019
The transcriptional modulator interferon‐related developmental regulator 1 in osteoblasts suppresses bone formation and promotes bone resorption
T Iezaki, Y Onishi, K Ozaki, K Fukasawa, Y Takahata, Y Nakamura, ...
Journal of Bone and Mineral Research 31 (3), 573-584, 2016
292016
Transcriptional modulator Ifrd1 regulates osteoclast differentiation through enhancing the NF-κB/NFATc1 pathway
T Iezaki, K Fukasawa, G Park, T Horie, T Kanayama, K Ozaki, Y Onishi, ...
Molecular and cellular biology 36 (19), 2451-2463, 2016
262016
The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis
T Iezaki, K Fukasawa, T Horie, G Park, S Robinson, M Nakaya, H Fujita, ...
Development 145 (14), dev164004, 2018
252018
mTORC1 activation in osteoclasts prevents bone loss in a mouse model of osteoporosis
M Hiraiwa, K Ozaki, T Yamada, T Iezaki, G Park, K Fukasawa, T Horie, ...
Frontiers in pharmacology 10, 684, 2019
242019
Hypoxia affects Slc7a5 expression through HIF‐2α in differentiated neuronal cells
Y Onishi, M Hiraiwa, H Kamada, T Iezaki, T Yamada, K Kaneda, E Hinoi
FEBS Open Bio 9 (2), 241-247, 2019
212019
The transcription factor paired box‐5 promotes osteoblastogenesis through direct induction of Osterix and Osteocalcin
E Hinoi, E Nakatani, T Yamamoto, T Iezaki, Y Takahata, H Fujita, R Ishiura, ...
Journal of Bone and Mineral Research 27 (12), 2526-2534, 2012
192012
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