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Genetic analysis of Runx2 function during intramembranous ossification T Takarada, R Nakazato, A Tsuchikane, K Fujikawa, T Iezaki, Y Yoneda, ... Development 143 (2), 211-218, 2016 | 108 | 2016 |
Bone resorption is regulated by circadian clock in osteoblasts T Takarada, C Xu, H Ochi, R Nakazato, D Yamada, S Nakamura, ... Journal of Bone and Mineral Research 32 (4), 872-881, 2017 | 103 | 2017 |
Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia E Hinoi, H Ochi, T Takarada, E Nakatani, T Iezaki, H Nakajima, H Fujita, ... Journal of bone and mineral research 27 (4), 938-949, 2012 | 89 | 2012 |
The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice T Yamamoto, E Hinoi, H Fujita, T Iezaki, Y Takahata, M Takamori, ... British journal of pharmacology 166 (3), 1084-1096, 2012 | 83 | 2012 |
ATF3 deficiency in chondrocytes alleviates osteoarthritis development T Iezaki, K Ozaki, K Fukasawa, M Inoue, S Kitajima, T Muneta, S Takeda, ... The Journal of pathology 239 (4), 426-437, 2016 | 58 | 2016 |
Growth differentiation factor-5 promotes brown adipogenesis in systemic energy expenditure E Hinoi, Y Nakamura, S Takada, H Fujita, T Iezaki, S Hashizume, ... Diabetes 63 (1), 162-175, 2014 | 56 | 2014 |
PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway E Hinoi, T Iezaki, H Fujita, T Watanabe, Y Odaka, K Ozaki, Y Yoneda Biochemical and biophysical research communications 450 (1), 255-260, 2014 | 41 | 2014 |
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway K Fukasawa, T Kadota, T Horie, K Tokumura, R Terada, Y Kitaguchi, ... Oncogene 40 (15), 2803-2815, 2021 | 37 | 2021 |
ATF3 controls proliferation of osteoclast precursor and bone remodeling K Fukasawa, G Park, T Iezaki, T Horie, T Kanayama, K Ozaki, Y Onishi, ... Scientific reports 6 (1), 30918, 2016 | 37 | 2016 |
Repression of adipogenesis through promotion of Wnt/β-catenin signaling by TIS7 up-regulated in adipocytes under hypoxia Y Nakamura, E Hinoi, T Iezaki, S Takada, S Hashizume, Y Takahata, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (8 …, 2013 | 37 | 2013 |
Daily intake of β-cryptoxanthin prevents bone loss by preferential disturbance of osteoclastic activation in ovariectomized mice K Ozaki, M Okamoto, K Fukasawa, T Iezaki, Y Onishi, Y Yoneda, ... Journal of Pharmacological Sciences 129 (1), 72-77, 2015 | 34 | 2015 |
Translational control of Sox9 RNA by mTORC1 contributes to skeletogenesis T Iezaki, T Horie, K Fukasawa, M Kitabatake, Y Nakamura, G Park, ... Stem Cell Reports 11 (1), 228-241, 2018 | 31 | 2018 |
The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway K Ozaki, T Yamada, T Horie, A Ishizaki, M Hiraiwa, T Iezaki, G Park, ... Science signaling 12 (589), eaaw3921, 2019 | 29 | 2019 |
The transcriptional modulator interferon‐related developmental regulator 1 in osteoblasts suppresses bone formation and promotes bone resorption T Iezaki, Y Onishi, K Ozaki, K Fukasawa, Y Takahata, Y Nakamura, ... Journal of Bone and Mineral Research 31 (3), 573-584, 2016 | 29 | 2016 |
Transcriptional modulator Ifrd1 regulates osteoclast differentiation through enhancing the NF-κB/NFATc1 pathway T Iezaki, K Fukasawa, G Park, T Horie, T Kanayama, K Ozaki, Y Onishi, ... Molecular and cellular biology 36 (19), 2451-2463, 2016 | 26 | 2016 |
The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis T Iezaki, K Fukasawa, T Horie, G Park, S Robinson, M Nakaya, H Fujita, ... Development 145 (14), dev164004, 2018 | 25 | 2018 |
mTORC1 activation in osteoclasts prevents bone loss in a mouse model of osteoporosis M Hiraiwa, K Ozaki, T Yamada, T Iezaki, G Park, K Fukasawa, T Horie, ... Frontiers in pharmacology 10, 684, 2019 | 24 | 2019 |
Hypoxia affects Slc7a5 expression through HIF‐2α in differentiated neuronal cells Y Onishi, M Hiraiwa, H Kamada, T Iezaki, T Yamada, K Kaneda, E Hinoi FEBS Open Bio 9 (2), 241-247, 2019 | 21 | 2019 |
The transcription factor paired box‐5 promotes osteoblastogenesis through direct induction of Osterix and Osteocalcin E Hinoi, E Nakatani, T Yamamoto, T Iezaki, Y Takahata, H Fujita, R Ishiura, ... Journal of Bone and Mineral Research 27 (12), 2526-2534, 2012 | 19 | 2012 |