Selenoproteins: molecular pathways and physiological roles VM Labunskyy, DL Hatfield, VN Gladyshev Physiological reviews 94 (3), 739-777, 2014 | 1235 | 2014 |
NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family AD Ferguson, VM Labunskyy, DE Fomenko, D Araç, Y Chelliah, ... Journal of Biological Chemistry 281 (6), 3536-3543, 2006 | 257 | 2006 |
Structure–function relations, physiological roles, and evolution of mammalian ER-resident selenoproteins VA Shchedrina, Y Zhang, VM Labunskyy, DL Hatfield, VN Gladyshev Antioxidants & redox signaling 12 (7), 839-849, 2010 | 235 | 2010 |
Both maximal expression of selenoproteins and selenoprotein deficiency can promote development of type 2 diabetes-like phenotype in mice VM Labunskyy, BC Lee, DE Handy, J Loscalzo, DL Hatfield, ... Antioxidants & redox signaling 14 (12), 2327-2336, 2011 | 206 | 2011 |
The Sep15 protein family: roles in disulfide bond formation and quality control in the endoplasmic reticulum VM Labunskyy, DL Hatfield, VN Gladyshev IUBMB life 59 (1), 1-5, 2007 | 147 | 2007 |
Role of reactive oxygen species-mediated signaling in aging VM Labunskyy, VN Gladyshev Antioxidants & redox signaling 19 (12), 1362-1372, 2013 | 138 | 2013 |
Sep15, a thioredoxin-like selenoprotein, is involved in the unfolded protein response and differentially regulated by adaptive and acute ER stresses VM Labunskyy, MH Yoo, DL Hatfield, VN Gladyshev Biochemistry 48 (35), 8458-8465, 2009 | 135 | 2009 |
Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice SV Novoselov, DF Calvisi, VM Labunskyy, VM Factor, BA Carlson, ... Oncogene 24 (54), 8003-8011, 2005 | 132 | 2005 |
Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice MV Kasaikina, DE Fomenko, VM Labunskyy, SA Lachke, W Qiu, ... Journal of Biological Chemistry 286 (38), 33203-33212, 2011 | 128 | 2011 |
X-ray fluorescence microscopy reveals the role of selenium in spermatogenesis S Kehr, M Malinouski, L Finney, S Vogt, VM Labunskyy, MV Kasaikina, ... Journal of molecular biology 389 (5), 808-818, 2009 | 114 | 2009 |
A novel cysteine-rich domain of Sep15 mediates the interaction with UDP-glucose: glycoprotein glucosyltransferase VM Labunskyy, AD Ferguson, DE Fomenko, Y Chelliah, DL Hatfield, ... Journal of Biological Chemistry 280 (45), 37839-37845, 2005 | 112 | 2005 |
HC gp-39 gene is upregulated in glioblastomas K Shostak, V Labunskyy, V Dmitrenko, T Malisheva, M Shamayev, ... Cancer letters 198 (2), 203-210, 2003 | 95 | 2003 |
Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection Y Suzuki, RP St Onge, R Mani, OD King, A Heilbut, VM Labunskyy, ... Nature methods 8 (2), 159-164, 2011 | 93 | 2011 |
Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response VM Labunskyy, MV Gerashchenko, JR Delaney, A Kaya, BK Kennedy, ... PLoS Genetics 10 (1), e1004019, 2014 | 88 | 2014 |
Selenoprotein T deficiency alters cell adhesion and elevates selenoprotein W expression in murine fibroblast cells A Sengupta, BA Carlson, VM Labunskyy, VN Gladyshev, DL Hatfield Biochemistry and Cell Biology 87 (6), 953-961, 2009 | 72 | 2009 |
Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast C Beaupere, L Dinatto, BM Wasko, RB Chen, L VanValkenburg, ... Proceedings of the National Academy of Sciences 115 (38), 9586-9591, 2018 | 43 | 2018 |
N-terminal acetylation promotes synaptonemal complex assembly in C. elegans J Gao, C Barroso, P Zhang, HM Kim, S Li, L Labrador, J Lightfoot, ... Genes & development 30 (21), 2404-2416, 2016 | 38 | 2016 |
Emerging omics approaches in aging research JS Lorusso, OA Sviderskiy, VM Labunskyy Antioxidants & redox signaling 29 (10), 985-1002, 2018 | 30 | 2018 |
CAN1 arginine permease deficiency extends yeast replicative lifespan via translational activation of stress response genes C Beaupere, BM Wasko, J Lorusso, BK Kennedy, M Kaeberlein, ... Cell reports 18 (8), 1884-1892, 2017 | 23 | 2017 |
The insertion Green Monster (iGM) method for expression of multiple exogenous genes in yeast VM Labunskyy, Y Suzuki, TJ Hanly, A Murao, FP Roth, VN Gladyshev G3: Genes, Genomes, Genetics 4 (7), 1183-1191, 2014 | 18 | 2014 |