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A. Hunter Shain
A. Hunter Shain
Associate Professor, Dermatology UCSF
Verified email at derm.ucsf.edu - Homepage
Title
Cited by
Cited by
Year
CNVkit: genome-wide copy number detection and visualization from targeted DNA sequencing
E Talevich, AH Shain, T Botton, BC Bastian
PLoS computational biology 12 (4), e1004873, 2016
14682016
The genetic evolution of melanoma from precursor lesions
AH Shain, I Yeh, I Kovalyshyn, A Sriharan, E Talevich, A Gagnon, ...
New England Journal of Medicine 373 (20), 1926-1936, 2015
10702015
From melanocytes to melanomas
AH Shain, BC Bastian
nature reviews Cancer 16 (6), 345-358, 2016
8782016
The spectrum of SWI/SNF mutations, ubiquitous in human cancers
AH Shain, JR Pollack
PloS one 8 (1), e55119, 2013
5912013
Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism
K Chiba, FK Lorbeer, AH Shain, DT McSwiggen, E Schruf, A Oh, J Ryu, ...
Science 357 (6358), 1416-1420, 2017
2662017
Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer
AH Shain, CP Giacomini, K Matsukuma, CA Karikari, MD Bashyam, ...
Proceedings of the National Academy of Sciences 109 (5), E252-E259, 2012
2652012
Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway
AH Shain, M Garrido, T Botton, E Talevich, I Yeh, JZ Sanborn, J Chung, ...
Nature genetics 47 (10), 1194-1199, 2015
2512015
Activating MET kinase rearrangements in melanoma and Spitz tumours
I Yeh, T Botton, E Talevich, AH Shain, AJ Sparatta, A de La Fouchardiere, ...
Nature communications 6 (1), 7174, 2015
2392015
Genomic and transcriptomic analysis reveals incremental disruption of key signaling pathways during melanoma evolution
AH Shain, NM Joseph, R Yu, J Benhamida, S Liu, T Prow, B Ruben, ...
Cancer cell 34 (1), 45-55. e4, 2018
1852018
The genetic evolution of metastatic uveal melanoma
AH Shain, MM Bagger, R Yu, D Chang, S Liu, S Vemula, JF Weier, ...
Nature genetics 51 (7), 1123-1130, 2019
1772019
NTRK3 kinase fusions in Spitz tumours
I Yeh, MK Tee, T Botton, AH Shain, AJ Sparatta, A Gagnon, SS Vemula, ...
The Journal of pathology 240 (3), 282-290, 2016
1412016
Targeted genomic profiling of acral melanoma
I Yeh, E Jorgenson, L Shen, M Xu, JP North, AH Shain, D Reuss, H Wu, ...
JNCI: Journal of the National Cancer Institute 111 (10), 1068-1077, 2019
1402019
Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types
CP Giacomini, S Sun, S Varma, AH Shain, MM Giacomini, J Balagtas, ...
PLoS genetics 9 (4), e1003464, 2013
1292013
Bi-allelic loss of CDKN2A initiates melanoma invasion via BRN2 activation
H Zeng, A Jorapur, AH Shain, UE Lang, R Torres, Y Zhang, AS McNeal, ...
Cancer cell 34 (1), 56-68. e9, 2018
1232018
Development of an orthotopic model of invasive pancreatic cancer in an immunocompetent murine host
WW Tseng, D Winer, JA Kenkel, O Choi, AH Shain, JR Pollack, R French, ...
Clinical Cancer Research 16 (14), 3684-3695, 2010
1212010
Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi
I Yeh, UE Lang, E Durieux, MK Tee, A Jorapur, AH Shain, V Haddad, ...
Nature communications 8 (1), 644, 2017
1162017
The genomic landscapes of individual melanocytes from human skin
J Tang, E Fewings, D Chang, H Zeng, S Liu, A Jorapur, RL Belote, ...
Nature 586 (7830), 600-605, 2020
992020
Genomic profiling of combined hepatocellular‐cholangiocarcinoma reveals similar genetics to hepatocellular carcinoma
NM Joseph, CG Tsokos, SE Umetsu, AH Shain, RK Kelley, C Onodera, ...
The Journal of pathology 248 (2), 164-178, 2019
812019
Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma
W Cao, H Lee, W Wu, A Zaman, S McCorkle, M Yan, J Chen, Q Xing, ...
Nature communications 11 (1), 3675, 2020
772020
Genetic heterogeneity of BRAF fusion kinases in melanoma affects drug responses
T Botton, E Talevich, VK Mishra, T Zhang, AH Shain, C Berquet, ...
Cell reports 29 (3), 573-588. e7, 2019
732019
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