p110δ, a novel phosphoinositide 3-kinase in leukocytes B Vanhaesebroeck, MJ Welham, K Kotani, R Stein, PH Warne, ... Proceedings of the National Academy of Sciences 94 (9), 4330-4335, 1997 | 605 | 1997 |
Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling NRD Paling, H Wheadon, HK Bone, MJ Welham Journal of Biological Chemistry 279 (46), 48063-48070, 2004 | 531 | 2004 |
Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing K Wright, N Rooney, M Feeney, J Tate, D Robertson, M Welham, S Ward Gastroenterology 129 (2), 437-453, 2005 | 408 | 2005 |
p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein. V Duronio, MJ Welham, S Abraham, P Dryden, JW Schrader Proceedings of the National Academy of Sciences 89 (5), 1587-1591, 1992 | 256 | 1992 |
Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) T Akasaka, T Balasas, LJ Russell, K Sugimoto, A Majid, R Walewska, ... Blood 109 (8), 3451-3461, 2007 | 233 | 2007 |
Interleukin-13 signal transduction in lymphohemopoietic cells: similarities and differences in signal transduction with interleukin-4 and insulin MJ Welham, L Learmonth, H Bone, JW Schrader Journal of Biological Chemistry 270 (20), 12286-12296, 1995 | 199 | 1995 |
Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells MP Storm, HK Bone, CG Beck, PY Bourillot, V Schreiber, T Damiano, ... Journal of Biological Chemistry 282 (9), 6265-6273, 2007 | 187 | 2007 |
Multiple hemopoietic growth factors stimulate activation of mitogen-activated protein kinase family members. MJ Welham, V Duronio, JS Sanghera, SL Pelech, JW Schrader Journal of immunology (Baltimore, Md.: 1950) 149 (5), 1683-1693, 1992 | 179 | 1992 |
Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and … MJ Welham, U Dechert, KB Leslie, F Jirik, JW Schrader Journal of Biological Chemistry 269 (38), 23764-23768, 1994 | 175 | 1994 |
Autophosphorylation of p110δ phosphoinositide 3‐kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo B Vanhaesebroeck, K Higashi, C Raven, M Welham, S Anderson, ... The EMBO journal, 1999 | 146 | 1999 |
A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3 HK Bone, AS Nelson, CE Goldring, D Tosh, MJ Welham Journal of cell science 124 (12), 1992-2000, 2011 | 137 | 2011 |
Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling BL Craddock, EA Orchiston, HJ Hinton, MJ Welham Journal of Biological Chemistry 274 (15), 10633-10640, 1999 | 124 | 1999 |
Multiple hemopoietins, with the exception of interleukin-4, induce modification of Shc and mSos1, but not their translocation. MJ Welham, V Duronio, KB Leslie, D Bowtell, JW Schrader Journal of Biological Chemistry 269 (33), 21165-21176, 1994 | 124 | 1994 |
The PI3K inhibitor arsenal: choose your weapon! T Crabbe, MJ Welham, SG Ward Trends in biochemical sciences 32 (10), 450-456, 2007 | 113 | 2007 |
Three‐dimensional culture systems for the expansion of pluripotent embryonic stem cells MP Storm, CB Orchard, HK Bone, JB Chaudhuri, MJ Welham Biotechnology and bioengineering 107 (4), 683-695, 2010 | 107 | 2010 |
Cytokine-induced protein kinase B activation and Bad phosphorylation do not correlate with cell survival of hemopoietic cells HJ Hinton, MJ Welham The Journal of Immunology 162 (12), 7002-7009, 1999 | 105 | 1999 |
Interleukin-4-dependent proliferation dissociates p44erk-1, p42erk-2, and p21ras activation from cell growth. MJ Welham, V Duronio, JW Schrader Journal of Biological Chemistry 269 (8), 5865-5873, 1994 | 97 | 1994 |
High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells V Turinetto, L Orlando, Y Sanchez-Ripoll, B Kumpfmueller, MP Storm, ... stem cells 30 (7), 1414-1423, 2012 | 93 | 2012 |
SHP1 and SHP2 protein-tyrosine phosphatases associate with βc after Interleukin-3-induced receptor tyrosine phosphorylation: Identification OF potential binding sites and … H Bone, U Dechert, F Jirik, JW Schrader, MJ Welham Journal of Biological Chemistry 272 (22), 14470-14476, 1997 | 91 | 1997 |
Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells MJ Welham, H Bone, M Levings, L Learmonth, LM Wang, KB Leslie, ... Journal of Biological Chemistry 272 (2), 1377-1381, 1997 | 81 | 1997 |