| Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials A Lin, CJ Giuliano, A Palladino, KM John, C Abramowicz, ML Yuan, ... Science translational medicine 11 (509), eaaw8412, 2019 | 532 | 2019 |
| CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials A Lin, CJ Giuliano, NM Sayles, JM Sheltzer Elife 6, e24179, 2017 | 135 | 2017 |
| Generating Single Cell–Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9 CJ Giuliano, A Lin, V Girish, JM Sheltzer Current Protocols in Molecular Biology 128, 2019 | 119 | 2019 |
| MELK expression correlates with tumor mitotic activity but is not required for cancer growth CJ Giuliano, A Lin, JC Smith, AC Palladino, JM Sheltzer Elife 7, e32838, 2018 | 85 | 2018 |
| 3D cell culture models and organ‐on‐a‐chip: Meet separation science and mass spectrometry A Lin, F Sved Skottvoll, S Rayner, S Pedersen‐Bjergaard, G Sullivan, ... Electrophoresis 41 (1-2), 56-64, 2020 | 60 | 2020 |
| Discovering and validating cancer genetic dependencies: approaches and pitfalls A Lin, JM Sheltzer Nature Reviews Genetics 21 (11), 671-682, 2020 | 48 | 2020 |
| Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials. Sci. Transl. Med. 11: eaaw8412 A Lin, CJ Giuliano, A Palladino, KM John, C Abramowicz, ML Yuan, ... | 16 | 2019 |
| Abstract 2149A: CRISPR/Cas9 mutagenesis invalidates a genetic target of clinical trials in cancer A Lin, C Giuliano, N Sayles, J Smith, J Sheltzer Cancer Research 77 (13 Supplement), 2149A-2149A, 2017 | | 2017 |
| Identification and characterization of survival-associated genomic features across tumor types J Smith, A Lin, C Giuliano, JM Sheltzer Cancer Research 77 (13 Supplement), 390-390, 2017 | | 2017 |
| Combining CRISPR/Cas9 mutagenesis and a small-molecule inhibitor to probe the function of MELK in cancer CJ Giuliano, A Lin, JC Smith, AC Palladino, JM Sheltzer bioRxiv, 203984, 2017 | | 2017 |
Jason SheltzerAssistant Professor, Yale School of MedicineVerified email at yale.edu
