| A Computational Study of Feedback Effects on Signal Dynamics in a Mitogen‐Activated Protein Kinase (MAPK) Pathway Model AR Asthagiri, DA Lauffenburger Biotechnology Progress 17 (2), 227-239, 2001 | 260 | 2001 |
| Bioengineering models of cell signaling AR Asthagiri, DA Lauffenburger Annual Review of Biomedical Engineering 2 (1), 31-53, 2000 | 223 | 2000 |
| Quantitative relationship among integrin-ligand binding, adhesion, and signaling via focal adhesion kinase and extracellular signal-regulated kinase 2 AR Asthagiri, CM Nelson, AF Horwitz, DA Lauffenburger Journal of Biological Chemistry 274 (38), 27119-27127, 1999 | 133 | 1999 |
| Matrix stiffening sensitizes epithelial cells to EGF and enables the loss of contact inhibition of proliferation JH Kim, AR Asthagiri Journal of cell science 124 (8), 1280-1287, 2011 | 118 | 2011 |
| Tunable interplay between epidermal growth factor and cell–cell contact governs the spatial dynamics of epithelial growth JH Kim, K Kushiro, NA Graham, AR Asthagiri Proceedings of the National Academy of Sciences 106 (27), 11149-11153, 2009 | 77 | 2009 |
| Intercellular coupling amplifies fate segregation during Caenorhabditis elegans vulval development CA Giurumescu, PW Sternberg, AR Asthagiri Proceedings of the National Academy of Sciences of the United States of …, 2006 | 69 | 2006 |
| Quantitative effect of scaffold abundance on signal propagation SA Chapman, AR Asthagiri Molecular systems biology 5 (1), 2009 | 60 | 2009 |
| Reprogramming directional cell motility by tuning micropattern features and cellular signals K Kushiro, S Chang, AR Asthagiri Advanced Materials 22 (40), 4516-4519, 2010 | 58 | 2010 |
| The role of transient ERK2 signals in fibronectin-and insulin-mediated DNA synthesis AR Asthagiri, CA Reinhart, AF Horwitz, DA Lauffenburger Journal of cell science 113 (24), 4499-4510, 2000 | 47 | 2000 |
| Epidermal growth factor-mediated T-cell factor/lymphoid enhancer factor transcriptional activity is essential but not sufficient for cell cycle progression in nontransformed … NA Graham, AR Asthagiri Journal of Biological Chemistry 279 (22), 23517-23524, 2004 | 40 | 2004 |
| Collective Migration Exhibits Greater Sensitivity But Slower Dynamics of Alignment to Applied Electric Fields ML Lalli, AR Asthagiri Cellular and molecular bioengineering 8 (2), 247-257, 2015 | 38 | 2015 |
| Quantitatively distinct requirements for signaling-competent cell spreading on engineered versus natural adhesion ligands GP Richman, DA Tirrell, AR Asthagiri Journal of controlled release 101 (1), 3-12, 2005 | 36 | 2005 |
| Modular design of micropattern geometry achieves combinatorial enhancements in cell motility K Kushiro, AR Asthagiri Langmuir 28 (9), 4357-4362, 2012 | 35 | 2012 |
| Regulators of Metastasis Modulate the Migratory Response to Cell Contact under Spatial Confinement DF Milano, NA Ngai, SK Muthuswamy, AR Asthagiri Biophysical journal 110 (8), 1886-1895, 2016 | 34 | 2016 |
| Intercellular mechanotransduction during multicellular morphodynamics JH Kim, LJ Dooling, AR Asthagiri Journal of The Royal Society Interface 7 (Suppl 3), S341-S350, 2010 | 33 | 2010 |
| Three-dimensional analysis of the effect of epidermal growth factor on cell-cell adhesion in epithelial cell clusters J Notbohm, JH Kim, AR Asthagiri, G Ravichandran Biophysical journal 102 (6), 1323-1330, 2012 | 30 | 2012 |
| Predicting phenotypic diversity and the underlying quantitative molecular transitions CA Giurumescu, PW Sternberg, AR Asthagiri PLoS computational biology 5 (4), e1000354, 2009 | 30 | 2009 |
| Resistance to signal activation governs design features of the MAP kinase signaling module S Chapman, AR Asthagiri Biotechnology and bioengineering 85 (3), 311-322, 2004 | 30 | 2004 |
| A rapid and sensitive quantitative kinase activity assay using a convenient 96-well format AR Asthagiri, AF Horwitz, DA Lauffenburger Analytical biochemistry 269 (2), 342-347, 1999 | 25 | 1999 |
| FGF signaling regulates Wnt ligand expression to control vulval cell lineage polarity in C. elegans PJ Minor, TF He, CH Sohn, AR Asthagiri, PW Sternberg Development 140 (18), 3882-3891, 2013 | 21 | 2013 |
Celeste M. NelsonWilke Family Professor in Bioengineering and Professor of Chemical & Biological EngineeringVerified email at princeton.edu
