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George Laliotis
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Protein arginine methyltransferase 5 promotes cholesterol biosynthesis–mediated Th17 responses and autoimmunity
LM Webb, S Sengupta, C Edell, ZL Piedra-Quintero, SA Amici, ...
The Journal of clinical investigation 130 (4), 1683-1698, 2020
532020
Targeting phosphatidylinositol 3 kinase-β and-δ for Bruton tyrosine kinase resistance in diffuse large B-cell lymphoma
N Jain, S Singh, G Laliotis, A Hart, E Muhowski, K Kupcova, T Chrbolkova, ...
Blood Advances 4 (18), 4382-4392, 2020
242020
Integration of metabolomics and gene expression profiling elucidates IL4I1 as modulator of ibrutinib resistance in ABC-diffuse large B cell lymphoma
F Choueiry, S Singh, A Sircar, G Laliotis, X Sun, E Chavdoula, S Zhang, ...
Cancers 13 (9), 2146, 2021
142021
Kinetics of postoperative circulating cell-free DNA and impact on minimal residual disease detection rates in patients with resected stage I-III colorectal cancer.
SA Cohen, PM Kasi, VN Aushev, DL Hanna, GP Botta, S Sharif, ...
Journal of clinical oncology 41 (4_suppl), 5-5, 2023
122023
RNAdetector: a free user-friendly stand-alone and cloud-based system for RNA-Seq data analysis
A La Ferlita, S Alaimo, S Di Bella, E Martorana, GI Laliotis, F Bertoni, ...
BMC bioinformatics 22 (1), 298, 2021
122021
Interpretable deep learning for chromatin-informed inference of transcriptional programs driven by somatic alterations across cancers
Y Tao, X Ma, D Palmer, R Schwartz, X Lu, HU Osmanbeyoglu
Nucleic Acids Research 50 (19), 10869-10881, 2022
72022
The present and future of clinical management in metastatic breast cancer
PH Lin, G Laliotis
Journal of clinical medicine 11 (19), 5891, 2022
62022
The oncogenic PI3K-induced transcriptomic landscape reveals key functions in splicing and gene expression regulation
E Ladewig, F Michelini, K Jhaveri, P Castel, J Carmona, L Fairchild, ...
Cancer research 82 (12), 2269-2280, 2022
62022
PRMT5 promotes symmetric dimethylation of RNA processing proteins and modulates activated T cell alternative splicing and Ca2+/NFAT signaling
S Sengupta, KO West, S Sanghvi, G Laliotis, LM Agosto, KW Lynch, ...
Immunohorizons 5 (10), 884-897, 2021
62021
Use of cetuximab added to weekly chemotherapy to improve progression-free survival in patients with recurrent metastatic head and neck squamous cell carcinoma after progression …
M Issa, B Klamer, V Karivedu, P Bhateja, GI Laliotis, K Dibs, N Mladkova, ...
Journal of Clinical Oncology 39 (15_suppl), 6038-6038, 2021
62021
Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial
YL Verschoor, J van de Haar, JG van den Berg, JW van Sandick, ...
Nature medicine, 1-12, 2024
52024
Circulating tumor DNA analysis in advanced urothelial carcinoma: insights from biological analysis and extended clinical follow-up
SV Lindskrog, K Birkenkamp-Demtröder, I Nordentoft, G Laliotis, P Lamy, ...
Clinical Cancer Research 29 (23), 4797-4807, 2023
52023
Effective identification of RNA-binding proteins using RNA Immunoprecipitation
GI Laliotis, PN Tsichlis
Protocols. io, dx 10, 2020
52020
Circulating tumor DNA dynamics as an early predictor of recurrence in patients with radically resected colorectal cancer: Updated results from GALAXY study in the CIRCULATE-Japan.
E Oki, D Kotani, Y Nakamura, S Mishima, H Bando, H Yukami, K Ando, ...
Journal of Clinical Oncology 41 (16_suppl), 3521-3521, 2023
42023
Abstract PO010: The inhibition of IWS1 phosphorylation promotes genomic instability, the cGAS/STING pathway activation and PD-L1 levels, through the U2AF2 alternative RNA …
GI Laliotis, E Chavdoula, A Kaba, A La Ferlita, V Anastas, A Orlacchio, ...
Cancer Immunology Research 9 (2_Supplement), PO010-PO010, 2021
42021
IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing
GI Laliotis, E Chavdoula, MD Paraskevopoulou, AD Kaba, A La Ferlita, ...
bioRxiv, 2020.07. 14.195297, 2020
42020
Utility of ctDNA in predicting outcome and pathological complete response in patients with bladder cancer as a guide for selective bladder preservation strategies.
L Dyrskjøt, G Laliotis MD, PhD, I Nordentoft, K Birkenkamp-Demtröder, ...
Journal of Clinical Oncology 41 (6_suppl), 563-563, 2023
32023
IWS1 phosphorylation controls nucleocytoplasmic export of type I IFNs and the sensitivity to oncolytic viruses, through U2AF2 RNA splicing
GI Laliotis, A Kenney, E Chavdoula, A La Ferlita, V Anastas, J Yount, ...
Mendeley Data 1, 10.17632, 2021
32021
Abstract PO-011: IWS1 phosphorylation promotes tumor growth and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the epigenetic regulation of U2AF2 …
GI Laliotis, E Chavdoula, MD Paraskevopoulou, A Kaba, A La Ferlita, ...
Cancer Research 80 (23_Supplement), PO-011-PO-011, 2020
32020
Abstract LB-183: Sensitivity of cancer cells to oncolytic viruses is defined by IWS1 phosphorylation dependent epigenetic regulation of U2AF2 splicing and nucleocytoplasmic …
GI Laliotis, AD Kenney, A Orlacchio, V Coppola, JS Yount, PN Tsichlis
Cancer Research 80 (16_Supplement), LB-183-LB-183, 2020
32020
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