Met receptor contributes to trastuzumab resistance of Her2-overexpressing breast cancer cells DL Shattuck, JK Miller, KL Carraway, C Sweeney Cancer research 68 (5), 1471-1477, 2008 | 522 | 2008 |
The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases MB Laederich, M Funes-Duran, L Yen, E Ingalla, X Wu, KL Carraway III, ... Journal of Biological Chemistry 279 (45), 47050-47056, 2004 | 287 | 2004 |
Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8 X Wu, L Yen, L Irwin, C Sweeney, KL Carraway III Molecular and cellular biology 24 (17), 7748-7757, 2004 | 203 | 2004 |
LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy DL Shattuck, JK Miller, M Laederich, M Funes, H Petersen, ... Molecular and cellular biology 27 (5), 1934-1946, 2007 | 156 | 2007 |
The phosphatidylinositol‐3 kinase pathway regulates bladder cancer cell invasion X Wu, T Obata, Q Khan, RA Highshaw, R De Vere White, C Sweeney BJU international 93 (1), 143-150, 2004 | 156 | 2004 |
Growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors C Sweeney, D Fambrough, C Huard, AJ Diamonti, ES Lander, LC Cantley, ... Journal of Biological Chemistry 276 (25), 22685-22698, 2001 | 156 | 2001 |
Ligand discrimination in signaling through an ErbB4 receptor homodimer C Sweeney, C Lai, DJ Riese II, AJ Diamonti, LC Cantley, KL Carraway III Journal of Biological Chemistry 275 (26), 19803-19807, 2000 | 153 | 2000 |
Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1 Z Cao, X Wu, L Yen, C Sweeney, KL Carraway III Molecular and cellular biology 27 (6), 2180-2188, 2007 | 149 | 2007 |
An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels AJ Diamonti, PM Guy, C Ivanof, K Wong, C Sweeney, KL Carraway Proceedings of the National Academy of Sciences 99 (5), 2866-2871, 2002 | 148 | 2002 |
Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer JK Miller, DL Shattuck, EQ Ingalla, L Yen, AD Borowsky, LJT Young, ... Cancer research 68 (20), 8286-8294, 2008 | 139 | 2008 |
Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl mediated down-regulation T Ravid, C Sweeney, P Gee, KL Carraway III, T Goldkorn Journal of Biological Chemistry 277 (34), 31214-31219, 2002 | 130 | 2002 |
Histidine phosphorylation of P-selectin upon stimulation of human platelets: a novel pathway for activation-dependent signal transduction CS Crovello, BC Furie, B Furie Cell 82 (2), 279-286, 1995 | 122 | 1995 |
Ligand discrimination by ErbB receptors: differential signaling through differential phosphorylation site usage C Sweeney, KL Carraway Oncogene 19 (49), 5568-5573, 2000 | 118 | 2000 |
LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII MA Stutz, DL Shattuck, MB Laederich, KL Carraway, C Sweeney Oncogene 27 (43), 5741-5752, 2008 | 114 | 2008 |
Differential signaling by the epidermal growth factor-like growth factors neuregulin-1 and neuregulin-2 CS Crovello, C Lai, LC Cantley, KL Carraway III Journal of Biological Chemistry 273 (41), 26954-26961, 1998 | 110 | 1998 |
The aryl hydrocarbon receptor (AhR) mediates resistance to apoptosis induced in breast cancer cells K Bekki, H Vogel, W Li, T Ito, C Sweeney, T Haarmann-Stemmann, ... Pesticide biochemistry and physiology 120, 5-13, 2015 | 100 | 2015 |
The mucin Muc4 potentiates neuregulin signaling by increasing the cell-surface populations of ErbB2 and ErbB3 M Funes, JK Miller, C Lai, KL Carraway III, C Sweeney Journal of Biological Chemistry 281 (28), 19310-19319, 2006 | 99 | 2006 |
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells D Candas-Green, B Xie, J Huang, M Fan, A Wang, C Menaa, Y Zhang, ... Nature Communications 11 (1), 1-15, 2020 | 97 | 2020 |
Contribution of membrane mucins to tumor progression through modulation of cellular growth signaling pathways KL Carraway III, M Funes, HC Workman, C Sweeney Current topics in developmental biology 78, 1-22, 2007 | 95 | 2007 |
The membrane mucin Muc4 inhibits apoptosis induced by multiple insults via ErbB2-dependent and ErbB2-independent mechanisms HC Workman, C Sweeney, KL Carraway Cancer research 69 (7), 2845-2852, 2009 | 90 | 2009 |