| Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice M Mattiazzi, M D'Aurelio, CD Gajewski, K Martushova, M Kiaei, MF Beal, ... Journal of biological chemistry 277 (33), 29626-29633, 2002 | 740 | 2002 |
| Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation R Acin-Perez, E Salazar, M Kamenetsky, J Buck, LR Levin, G Manfredi Cell metabolism 9 (3), 265-276, 2009 | 535 | 2009 |
| Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation P Mishra, V Carelli, G Manfredi, DC Chan Cell metabolism 19 (4), 630-641, 2014 | 473 | 2014 |
| Neuronal degeneration and mitochondrial dysfunction EA Schon, G Manfredi The Journal of clinical investigation 111 (3), 303-312, 2003 | 470 | 2003 |
| Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients FR Wiedemann, G Manfredi, C Mawrin, MF Beal, EA Schon Journal of neurochemistry 80 (4), 616-625, 2002 | 446 | 2002 |
| Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells DF Suen, DP Narendra, A Tanaka, G Manfredi, RJ Youle Proceedings of the National Academy of Sciences 107 (26), 11835-11840, 2010 | 366 | 2010 |
| Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models J Magrane, C Cortez, WB Gan, G Manfredi Human molecular genetics 23 (6), 1413-1424, 2014 | 365 | 2014 |
| Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis Y Shidara, K Yamagata, T Kanamori, K Nakano, JQ Kwong, G Manfredi, ... Cancer research 65 (5), 1655-1663, 2005 | 336 | 2005 |
| Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus G Manfredi, J Fu, J Ojaimi, JE Sadlock, JQ Kwong, J Guy, EA Schon Nature genetics 30 (4), 394-399, 2002 | 320 | 2002 |
| Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn‐superoxide dismutase mutant mice M Damiano, AA Starkov, S Petri, K Kipiani, M Kiaei, M Mattiazzi, ... Journal of neurochemistry 96 (5), 1349-1361, 2006 | 315 | 2006 |
| Rescue of a mitochondrial deficiency causing Leber hereditary optic neuropathy J Guy, X Qi, F Pallotti, EA Schon, G Manfredi, V Carelli, A Martinuzzi, ... Annals of Neurology: Official Journal of the American Neurological …, 2002 | 312 | 2002 |
| Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice C Vijayvergiya, MF Beal, J Buck, G Manfredi Journal of Neuroscience 25 (10), 2463-2470, 2005 | 306 | 2005 |
| IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity M Song, TA Sandoval, CS Chae, S Chopra, C Tan, MR Rutkowski, ... Nature 562 (7727), 423-428, 2018 | 305 | 2018 |
| Measurements of ATP in mammalian cells G Manfredi, L Yang, CD Gajewski, M Mattiazzi Methods 26 (4), 317-326, 2002 | 276 | 2002 |
| Mitochondrial dysfunction and its role in motor neuron degeneration in ALS G Manfredi, Z Xu Mitochondrion 5 (2), 77-87, 2005 | 251 | 2005 |
| The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants M Mattiazzi, C Vijayvergiya, CD Gajewski, DC DeVivo, G Lenaz, ... Human molecular genetics 13 (8), 869-879, 2004 | 241 | 2004 |
| Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice SM Cloonan, K Glass, ME Laucho-Contreras, AR Bhashyam, M Cervo, ... Nature medicine 22 (2), 163-174, 2016 | 226 | 2016 |
| The role of mitochondria in inherited neurodegenerative diseases JQ Kwong, MF Beal, G Manfredi Journal of neurochemistry 97 (6), 1659-1675, 2006 | 224 | 2006 |
| Mechanisms, models and biomarkers in amyotrophic lateral sclerosis MR Turner, R Bowser, L Bruijn, L Dupuis, A Ludolph, M McGrath, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14 (sup1), 19-32, 2013 | 212 | 2013 |
| Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission W Liu, R Acín-Peréz, KD Geghman, G Manfredi, B Lu, C Li Proceedings of the National Academy of Sciences 108 (31), 12920-12924, 2011 | 212 | 2011 |
