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Megan Ken
Megan Ken
Other namesMegan Kelly
Verified email at scripps.edu
Title
Cited by
Cited by
Year
The roles of structural dynamics in the cellular functions of RNAs
LR Ganser, ML Kelly, D Herschlag, HM Al-Hashimi
Nature Reviews Molecular Cell Biology 20 (8), 474-489, 2019
3752019
Neonatal nonepileptic myoclonus is a prominent clinical feature of KCNQ2 gain‐of‐function variants R201C and R201H
SB Mulkey, B Ben‐Zeev, J Nicolai, JL Carroll, S Grønborg, Y Jiang, ...
Epilepsia 58 (3), 436-445, 2017
892017
High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble
LR Ganser, J Lee, A Rangadurai, DK Merriman, ML Kelly, AD Kansal, ...
Nature structural & molecular biology 25 (5), 425-434, 2018
862018
A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites
AM Guggisberg, J Park, RL Edwards, ML Kelly, DM Hodge, NH Tolia, ...
Nature communications 5 (1), 4467, 2014
852014
Malaria parasites produce volatile mosquito attractants
M Kelly, CY Su, C Schaber, JR Crowley, FF Hsu, JR Carlson, AR Odom
MBio 6 (2), 10.1128/mbio. 00235-15, 2015
832015
Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum
R Howe, M Kelly, J Jimah, D Hodge, AR Odom
Eukaryotic cell 12 (2), 215-223, 2013
732013
Probing RNA conformational equilibria within the functional cellular context
LR Ganser, CC Chu, HP Bogerd, ML Kelly, BR Cullen, HM Al-Hashimi
Cell Reports 30 (8), 2472-2480. e4, 2020
342020
Demonstration that Small Molecules can Bind and Stabilize Low-abundance Short-lived RNA Excited Conformational States
LR Ganser, ML Kelly, NN Patwardhan, AE Hargrove, HM Al-Hashimi
Journal of Molecular Biology 432 (4), 1297-1304, 2020
282020
Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem–loop RNAs and their implications for functional cellular assays
ML Kelly, CC Chu, H Shi, LR Ganser, HP Bogerd, K Huynh, Y Hou, ...
RNA 27 (1), 12-26, 2021
182021
RNA conformational propensities determine cellular activity
ML Ken, R Roy, A Geng, LR Ganser, A Manghrani, BR Cullen, ...
Nature 617, 835-841, 2023
162023
Publisher Correction: High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble
LR Ganser, J Lee, A Rangadurai, DK Merriman, ML Kelly, AD Kansal, ...
Nature structural & molecular biology 27 (6), 604, 2020
22020
Stabilizing non-native excited states as a therapeutic strategy for targeting RNA
LR Ganser, CC Chu, HP Bogerd, ML Kelly, BR Cullen, HM Al-Hashimi
bioRxiv, 634576, 2019
12019
Cultivating creativity and belonging in science
M Ken
Cell Chemical Biology 31 (1), 6-9, 2024
2024
Development of a curriculum in cultural determinants of health and health disparities
ML Kelly, V Parente, R Redmond, R Willis, K Railey
Journal of the National Medical Association 115 (4), 428-435, 2023
2023
Stepwise Reconstitution of RNA Cellular Activity
ML Kelly
Duke University, 2022
2022
RNA conformational propensities determine cellular activity
ML Kelly, R Roy, A Geng, LR Ganser, A Manghrani, BR Cullen, ...
bioRxiv, 2022.12. 05.519207, 2022
2022
Understanding the role of bulge‐length dependent RNA stacking energetics in determining HIV‐1 TAR‐Tat peptide binding energetics in vitro and in cells
M Kelly, R Roy, H Bogerd, D Merriman, L Ganser, B Cullen, H Al‐Hashimi
The FASEB Journal 35, 2021
2021
Revealing the high propensity of RNAs to non-specifically bind drug-like small molecules
ML Kelly, CC Chu, H Shi, LR Ganser, HP Bogerd, K Huynh, Y Hou, ...
bioRxiv, 2020.05. 02.074336, 2020
2020
Elucidating the Identity and Function Volatile Organic Compounds (VOCs) Emitted by the Malaria Parasite, Plasmodium falciparum
M Kelly
2013
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Articles 1–19