| Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein KV Ledwitch, ME Gibbs, RW Barnes, AG Roberts Biochemical pharmacology 118, 96-108, 2016 | 53 | 2016 |
| Unravelling the complex drug–drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein KV Ledwitch, RW Barnes, AG Roberts Bioscience reports 36 (2), e00309, 2016 | 44 | 2016 |
| Cardiovascular ion channel inhibitor drug-drug interactions with P-glycoprotein KV Ledwitch, AG Roberts The AAPS journal 19, 409-420, 2017 | 33 | 2017 |
| Taxol: efficacy against oral squamous cell carcinoma K Ledwitch, R Ogburn, J Cox, R Graham, A Fritzsche, D Gosnell, ... Mini reviews in medicinal chemistry 13 (4), 509-521, 2013 | 24 | 2013 |
| A conformationally gated model of methadone and loperamide transport by P-glycoprotein ME Gibbs, LA Wilt, KV Ledwitch, AG Roberts Journal of pharmaceutical sciences 107 (7), 1937-1947, 2018 | 14 | 2018 |
| A unified structural model of the mammalian translocator protein (TSPO) Y Xia, K Ledwitch, G Kuenze, A Duran, J Li, CR Sanders, C Manning, ... Journal of biomolecular NMR 73, 347-364, 2019 | 13 | 2019 |
| Copper ion as a delivery platform for taxanes and taxane complexes TJ Manning, D Phillips, G Wylie, B Bythell, S Clark, R Ogburn, K Ledwitch, ... Bioorganic & Medicinal Chemistry Letters 24 (1), 371-377, 2014 | 12 | 2014 |
| Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia JI Aguilar, MH Cheng, J Font, AC Schwartz, K Ledwitch, A Duran, ... Elife 10, e68039, 2021 | 11 | 2021 |
| The role of cytochrome P450 BM3 phenylalanine-87 and threonine-268 in binding organic hydroperoxides AG Roberts, J Katayama, R Kaspera, KV Ledwitch, I Le Trong, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (4), 669-677, 2016 | 10 | 2016 |
| Targeting in silico GPCR conformations with ultra-large library screening for hit discovery D Sala, H Batebi, K Ledwitch, PW Hildebrand, J Meiler Trends in Pharmacological Sciences 44 (3), 150-161, 2023 | 8 | 2023 |
| Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region CT Schoeder, P Gilchuk, AK Sangha, KV Ledwitch, DC Malherbe, ... PLoS pathogens 18 (5), e1010518, 2022 | 7 | 2022 |
| Computational modeling and prediction of deletion mutants H Woods, DL Schiano, JI Aguirre, KV Ledwitch, EF McDonald, M Voehler, ... Structure 31 (6), 713-723. e3, 2023 | 5 | 2023 |
| Structural studies of the copper (II)-quinine complexes T Manning, R Ogburn, K Ledwitch, G Wylie, D Phillips Florida Scientist, 51-62, 2012 | 4 | 2012 |
| Boosted coupling of ATP hydrolysis to substrate transport upon cooperative estradiol-17-β-D-glucuronide binding in a Drosophila ATP binding cassette type-C transporter A Karasik, KV Ledwitch, T Arányi, A Váradi, A Roberts, F Szeri The FASEB Journal 32 (2), 669, 2018 | 3 | 2018 |
| Rosetta’s Predictive Ability for Low-Affinity Ligand Binding in Fragment-Based Drug Discovery E Okwei, ST Smith, BJ Bender, B Allison, S Ganguly, A Geanes, X Zhang, ... Biochemistry 62 (3), 700-709, 2023 | 2 | 2023 |
| First crystal structure of a non-canonical amino acid linked to a paramagnetic lanthanide tag facilitates protein structure determination using NMR-derived restraints E Okwei, S Ganguly, HL Darling, JM Harp, A Gulsevin, I Coin, ... bioRxiv, 2022.04. 10.487812, 2022 | 2 | 2022 |
| Copper Ion Delivery Platform for Pharmaceutical Agents TJ Manning, RN Ogburn, KV Ledwitch, DR Phillips, GP Wylie US Patent App. 13/418,235, 2013 | 2 | 2013 |
| Dark nanodiscs for evaluating membrane protein thermostability by differential scanning fluorimetry JA Selvasingh, EF McDonald, PD Neufer, JR McKinney, J Meiler, ... Biophysical Journal 123 (1), 68-79, 2024 | | 2024 |
| Sparse pseudocontact shift NMR data obtained from a non-canonical amino acid-linked lanthanide tag improves integral membrane protein structure prediction KV Ledwitch, G Künze, JR McKinney, E Okwei, K Larochelle, L Pankewitz, ... Journal of Biomolecular NMR 77 (3), 69-82, 2023 | | 2023 |
| Confirmation of association of TGFBI p.Ser591Phe mutation with variant lattice corneal dystrophy CH Choo, DD Chung, KV Ledwitch, A Kassels, J Meiler, AJ Aldave Ophthalmic genetics 43 (4), 530-533, 2022 | | 2022 |
Jens MeilerVanderbilt University & University LeipzigVerified email at meilerlab.org
