Update on mechanism and catalytic regulation in the NO synthases DJ Stuehr, J Santolini, ZQ Wang, CC Wei, S Adak Journal of Biological Chemistry 279 (35), 36167-36170, 2004 | 617 | 2004 |
Arginine conversion to nitroxide by tetrahydrobiopterin-free neuronal nitric-oxide synthase: implications for mechanism S Adak, Q Wang, DJ Stuehr Journal of Biological Chemistry 275 (43), 33554-33561, 2000 | 273 | 2000 |
Direct evidence for nitric oxide production by a nitric-oxide synthase-like protein from Bacillus subtilis S Adak, KS Aulak, DJ Stuehr Journal of Biological Chemistry 277 (18), 16167-16171, 2002 | 218 | 2002 |
Structure of a Nitric Oxide Synthase Heme Protein from Bacillus subtilis, K Pant, AM Bilwes, S Adak, DJ Stuehr, BR Crane Biochemistry 41 (37), 11071-11079, 2002 | 171 | 2002 |
Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans S Adak, AM Bilwes, K Panda, D Hosfield, KS Aulak, JF McDonald, ... Proceedings of the National Academy of Sciences 99 (1), 107-112, 2002 | 171 | 2002 |
Neuronal nitric-oxide synthase mutant (Ser-1412→ Asp) demonstrates surprising connections between heme reduction, NO complex formation, and catalysis S Adak, J Santolini, S Tikunova, Q Wang, JD Johnson, DJ Stuehr Journal of Biological Chemistry 276 (2), 1244-1252, 2001 | 131 | 2001 |
Endoplasmic reticulum stress-induced apoptosis in Leishmania through Ca2+-dependent and caspase-independent mechanism S Dolai, S Pal, RK Yadav, S Adak Journal of Biological Chemistry 286 (15), 13638-13646, 2011 | 124 | 2011 |
A kinetic simulation model that describes catalysis and regulation in nitric-oxide synthase J Santolini, S Adak, CML Curran, DJ Stuehr Journal of Biological Chemistry 276 (2), 1233-1243, 2001 | 116 | 2001 |
Leishmania major encodes an unusual peroxidase that is a close homologue of plant ascorbate peroxidase: a novel role of the transmembrane domain S Adak, AK Datta Biochemical Journal 390 (2), 465-474, 2005 | 106 | 2005 |
Role of reductase domain cluster 1 acidic residues in neuronal nitric-oxide synthase: Characterization of the FMN-free enzyme S Adak, S Ghosh, HM Abu-Soud, DJ Stuehr Journal of Biological Chemistry 274 (32), 22313-22320, 1999 | 104 | 1999 |
Ascorbate peroxidase from Leishmania major controls the virulence of infective stage of promastigotes by regulating oxidative stress S Pal, S Dolai, RK Yadav, S Adak PloS one 5 (6), e11271, 2010 | 88 | 2010 |
Regulation of the properties of the heme-NO complexes in nitric-oxide synthase by hydrogen bonding to the proximal cysteine M Couture, S Adak, DJ Stuehr, DL Rousseau Journal of Biological Chemistry 276 (41), 38280-38288, 2001 | 81 | 2001 |
Tryptophan 409 controls the activity of neuronal nitric-oxide synthase by regulating nitric oxide feedback inhibition S Adak, C Crooks, Q Wang, BR Crane, JA Tainer, ED Getzoff, DJ Stuehr Journal of Biological Chemistry 274 (38), 26907-26911, 1999 | 80 | 1999 |
Leishmania major ascorbate peroxidase overexpression protects cells against reactive oxygen species-mediated cardiolipin oxidation S Dolai, RK Yadav, S Pal, S Adak Free Radical Biology and Medicine 45 (11), 1520-1529, 2008 | 79 | 2008 |
Mutational analysis of the tetrahydrobiopterin-binding site in inducible nitric-oxide synthase S Ghosh, D Wolan, S Adak, BR Crane, NS Kwon, JA Tainer, ED Getzoff, ... Journal of Biological Chemistry 274 (34), 24100-24112, 1999 | 79 | 1999 |
Overexpression of Mitochondrial Leishmania major Ascorbate Peroxidase Enhances Tolerance to Oxidative Stress-Induced Programmed Cell Death and Protein … S Dolai, RK Yadav, S Pal, S Adak Eukaryotic cell 8 (11), 1721-1731, 2009 | 69 | 2009 |
A conserved flavin-shielding residue regulates NO synthase electron transfer and nicotinamide coenzyme specificity S Adak, M Sharma, AL Meade, DJ Stuehr Proceedings of the National Academy of Sciences 99 (21), 13516-13521, 2002 | 67 | 2002 |
Molecular basis for hyperactivity in tryptophan 409 mutants of neuronal NO synthase S Adak, Q Wang, DJ Stuehr Journal of Biological Chemistry 275 (23), 17434-17439, 2000 | 62 | 2000 |
Chimeras of nitric-oxide synthase types I and III establish fundamental correlates between heme reduction, heme-NO complex formation, and catalytic activity S Adak, KS Aulak, DJ Stuehr Journal of Biological Chemistry 276 (26), 23246-23252, 2001 | 53 | 2001 |
Low catalytic turnover of horseradish peroxidase in thiocyanate oxidation: Evidence for concurrent inactivation by cyanide generated through one-electron oxidation of thiocyanate S Adak, A Mazumdar, RK Banerjee Journal of Biological Chemistry 272 (17), 11049-11056, 1997 | 49 | 1997 |