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David Courtney
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Epitranscriptomic enhancement of influenza A virus gene expression and replication
DG Courtney, EM Kennedy, RE Dumm, HP Bogerd, K Tsai, NS Heaton, ...
Cell host & microbe 22 (3), 377-386. e5, 2017
1882017
Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression
DG Courtney, K Tsai, HP Bogerd, EM Kennedy, BA Law, A Emery, ...
Cell Host & Microbe 26 (2), 217-227, 2019
1492019
CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting
DG Courtney, JE Moore, SD Atkinson, E Maurizi, EHA Allen, DML Pedrioli, ...
Gene therapy 23 (1), 108-112, 2016
1302016
Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication
K Tsai, DG Courtney, BR Cullen
PLoS pathogens 14 (2), e1006919, 2018
1282018
Viral epitranscriptomics
EM Kennedy, DG Courtney, K Tsai, BR Cullen
Journal of virology 91 (9), 10.1128/jvi. 02263-16, 2017
872017
Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders
KA Christie, DG Courtney, LA DeDionisio, CC Shern, S Majumdar, ...
Scientific Reports 7 (1), 16174, 2017
762017
Extensive epitranscriptomic methylation of A and C residues on murine leukemia virus transcripts enhances viral gene expression
DG Courtney, A Chalem, HP Bogerd, BA Law, EM Kennedy, CL Holley, ...
MBio 10 (3), 10.1128/mbio. 01209-19, 2019
492019
Development of allele-specific gene-silencing siRNAs for TGFBI Arg124Cys in lattice corneal dystrophy type I
DG Courtney, SD Atkinson, JE Moore, E Maurizi, C Serafini, G Pellegrini, ...
Investigative ophthalmology & visual science 55 (2), 977-985, 2014
462014
siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy
DG Courtney, SD Atkinson, EHA Allen, JE Moore, CP Walsh, ...
Investigative ophthalmology & visual science 55 (5), 3352-3360, 2014
392014
Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication
K Tsai, DG Courtney, EM Kennedy, BR Cullen
Rna 24 (9), 1172-1182, 2018
372018
Protein composition of TGFBI-R124C-and TGFBI-R555W-associated aggregates suggests multiple mechanisms leading to lattice and granular corneal dystrophy
DG Courtney, ET Poulsen, S Kennedy, JE Moore, SD Atkinson, E Maurizi, ...
Investigative ophthalmology & visual science 56 (8), 4653-4661, 2015
302015
Post-transcriptional regulation of viral RNA through epitranscriptional modification
DG Courtney
Cells 10 (5), 1129, 2021
272021
Protection of corneal epithelial stem cells prevents ultraviolet A damage during corneal collagen cross-linking treatment for keratoconus
JE Moore, SD Atkinson, DT Azar, J Worthington, CS Downes, ...
British Journal of Ophthalmology 98 (2), 270-274, 2014
262014
Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy
EHA Allen, DG Courtney, SD Atkinson, JE Moore, L Mairs, ET Poulsen, ...
Human molecular genetics 25 (6), 1176-1191, 2016
232016
An endogenously activated antiviral state restricts SARS-CoV-2 infection in differentiated primary airway epithelial cells
L Broadbent, CGG Bamford, G Lopez Campos, S Manzoor, D Courtney, ...
PLoS One 17 (4), e0266412, 2022
172022
Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique
CM Campos, K Tsai, DG Courtney, HP Bogerd, CL Holley, BR Cullen
RNA 27 (11), 1400-1411, 2021
162021
A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors
KY Chen, T Krischuns, LO Varga, E Harigua-Souiai, S Paisant, A Zettor, ...
Antiviral Research 201, 105272, 2022
132022
A novel role for CRIM1 in the corneal response to UV and pterygium development
E Maurizi, D Schiroli, SD Atkinson, L Mairs, DG Courtney, B O'Hagan, ...
Experimental eye research 179, 75-92, 2019
132019
Genome editing using Staphylococcus aureus Cas9 in a canine model of glycogen storage disease Ia
B Arnson, HR Kang, ED Brooks, D Gheorghiu, E Ilich, D Courtney, ...
Molecular Therapy-Methods & Clinical Development 29, 108-119, 2023
42023
Comparison of SARS-CoV-2 evolution in paediatric primary airway epithelial cell cultures compared with vero-derived cell lines
CGG Bamford, L Broadbent, E Aranday-Cortes, M McCabe, J McKenna, ...
Viruses 14 (2), 325, 2022
42022
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