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Jinyang Li
Jinyang Li
Innovent Biologics, Suzhou, China
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EMT subtype influences epithelial plasticity and mode of cell migration
NM Aiello, R Maddipati, RJ Norgard, D Balli, J Li, S Yuan, T Yamazoe, ...
Developmental cell 45 (6), 681-695. e4, 2018
5872018
Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy
J Li, KT Byrne, F Yan, T Yamazoe, Z Chen, T Baslan, LP Richman, JH Lin, ...
Immunity 49 (1), 178-193. e7, 2018
5712018
Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer
M Ruscetti, JP Morris, R Mezzadra, J Russell, J Leibold, PB Romesser, ...
Cell 181 (2), 424-441. e21, 2020
2522020
Regulation of pH by carbonic anhydrase 9 mediates survival of pancreatic cancer cells with activated KRAS in response to hypoxia
PC McDonald, SC Chafe, WS Brown, S Saberi, M Swayampakula, ...
Gastroenterology 157 (3), 823-837, 2019
1682019
Tumor cell–intrinsic EPHA2 suppresses antitumor immunity by regulating PTGS2 (COX-2)
N Markosyan, J Li, YH Sun, LP Richman, JH Lin, F Yan, L Quinones, ...
The Journal of clinical investigation 129 (9), 3594-3609, 2019
1362019
Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade
CA Natale, J Li, J Zhang, A Dahal, T Dentchev, BZ Stanger, TW Ridky
elife 7, e31770, 2018
1202018
Epigenetic and transcriptional control of the epidermal growth factor receptor regulates the tumor immune microenvironment in pancreatic cancer
J Li, S Yuan, RJ Norgard, F Yan, YH Sun, IK Kim, AJ Merrell, Y Sela, ...
Cancer discovery 11 (3), 736-753, 2021
812021
Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism
S Shah, WJ Carriveau, J Li, SL Campbell, PK Kopinski, HW Lim, N Daurio, ...
Oncotarget 7 (28), 43713, 2016
692016
Overcoming adaptive resistance to KRAS and MEK inhibitors by co-targeting mTORC1/2 complexes in pancreatic cancer
WS Brown, PC McDonald, O Nemirovsky, S Awrey, SC Chafe, ...
Cell Reports Medicine 1 (8), 2020
652020
Global regulation of the histone mark H3K36me2 underlies epithelial plasticity and metastatic progression
S Yuan, R Natesan, FJ Sanchez-Rivera, J Li, NV Bhanu, T Yamazoe, ...
Cancer discovery 10 (6), 854-871, 2020
572020
Tumor cell–intrinsic USP22 suppresses antitumor immunity in pancreatic cancer
J Li, S Yuan, RJ Norgard, F Yan, T Yamazoe, A Blanco, BZ Stanger
Cancer immunology research 8 (3), 282-291, 2020
552020
Pharmacologic activation of the G protein–coupled estrogen receptor inhibits pancreatic ductal adenocarcinoma
CA Natale, J Li, JR Pitarresi, RJ Norgard, T Dentchev, BC Capell, ...
Cellular and Molecular Gastroenterology and Hepatology 10 (4), 868-880. e1, 2020
452020
How tumor cell dedifferentiation drives immune evasion and resistance to immunotherapy
J Li, BZ Stanger
Cancer research 80 (19), 4037-4041, 2020
422020
Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs
J Gui, F Zahedi, A Ortiz, C Cho, KV Katlinski, K Alicea-Torres, J Li, L Todd, ...
Nature cancer 1 (6), 603-619, 2020
422020
MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma
R Maddipati, RJ Norgard, T Baslan, KS Rathi, A Zhang, A Saeid, ...
Cancer discovery 12 (2), 542-561, 2022
402022
KAT6A and ENL form an epigenetic transcriptional control module to drive critical leukemogenic gene-expression programs
F Yan, J Li, J Milosevic, R Petroni, S Liu, Z Shi, S Yuan, JM Reynaga, Y Qi, ...
Cancer discovery 12 (3), 792-811, 2022
382022
Cell cycle regulation meets tumor immunosuppression
J Li, BZ Stanger
Trends in Immunology 41 (10), 859-863, 2020
372020
Calcium signaling induces a partial EMT
RJ Norgard, JR Pitarresi, R Maddipati, NM Aiello‐Couzo, D Balli, J Li, ...
EMBO reports 22 (9), e51872, 2021
362021
PTHrP drives pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability
JR Pitarresi, RJ Norgard, AM Chiarella, K Suzuki, B Bakir, V Sahu, J Li, ...
Cancer discovery 11 (7), 1774-1791, 2021
362021
cIAP1/2 antagonism eliminates MHC class I–negative tumors through T cell–dependent reprogramming of mononuclear phagocytes
K Roehle, L Qiang, KS Ventre, D Heid, LR Ali, P Lenehan, M Heckler, ...
Science translational medicine 13 (594), eabf5058, 2021
322021
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