Machine learning analysis of individual tumor lesions in four metastatic colorectal cancer clinical studies: linking tumor heterogeneity to overall survival D Vera-Yunca, P Girard, ZP Parra-Guillen, A Munafo, IF Trocóniz, ... The AAPS journal 22, 1-12, 2020 | 18 | 2020 |
Disease pharmacokinetic–pharmacodynamic modelling in acute intermittent porphyria to support the development of mRNA‐based therapies ZP Parra‐Guillen, A Fontanellas, L Jiang, D Jericó, P Martini, ... British Journal of Pharmacology 177 (14), 3168-3182, 2020 | 11 | 2020 |
Relevance of primary lesion location, tumour heterogeneity and genetic mutation demonstrated through tumour growth inhibition and overall survival modelling in metastatic … D Vera‐Yunca, ZP Parra‐Guillen, P Girard, IF Trocóniz, N Terranova British Journal of Clinical Pharmacology 88 (1), 166-177, 2022 | 7 | 2022 |
Computational disease model of phenobarbital-induced acute attacks in an acute intermittent porphyria mouse model D Vera-Yunca, I Serrano-Mendioroz, A Sampedro, D Jerico, IF Troconiz, ... Molecular Genetics and Metabolism 128 (3), 367-375, 2019 | 3 | 2019 |
Mechanistic modelling of enzyme‐restoration effects of new recombinant liver‐targeted proteins in acute intermittent porphyria D Vera‐Yunca, KM Cordoba, ZP Parra‐Guillen, D Jerico, A Fontanellas, ... British Journal of Pharmacology 179 (14), 3815-3830, 2022 | | 2022 |
Development of disease and drug models for rare diseases: Application to Acute Intermittent Porphyria. D Vera-Yunca Universidad de Navarra, 2022 | | 2022 |
Disease pharmacokinetic–pharmacodynamic modelling in acute intermittent porphyria to support the development of mRNA-based therapies JI Fernández-de-Trocóniz, ZP Parra-Guillen, A Fontanellas, ... | | 2020 |