| A comparison of real-time and endpoint cell viability assays for improved synthetic lethal drug validation A Single, H Beetham, BJ Telford, P Guilford, A Chen Journal of biomolecular screening 20 (10), 1286-1293, 2015 | 79 | 2015 |
| Animal models reflecting chronic obstructive pulmonary disease and related respiratory disorders: translating pre-clinical data into clinical relevance L Tanner, AB Single Journal of innate immunity 12 (3), 203-225, 2020 | 78 | 2020 |
| Synthetic lethal screens identify vulnerabilities in GPCR signaling and cytoskeletal organization in E-Cadherin–Deficient cells BJ Telford, A Chen, H Beetham, J Frick, TP Brew, CM Gould, A Single, ... Molecular cancer therapeutics 14 (5), 1213-1223, 2015 | 39 | 2015 |
| E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function TD Godwin, ST Kelly, TP Brew, NM Bougen-Zhukov, AB Single, A Chen, ... Gastric Cancer 22, 273-286, 2019 | 36 | 2019 |
| Allosteric AKT inhibitors target synthetic lethal vulnerabilities in E-cadherin-deficient cells N Bougen-Zhukov, Y Nouri, T Godwin, M Taylor, C Hakkaart, A Single, ... Cancers 11 (9), 1359, 2019 | 32 | 2019 |
| Chemotherapy as a regulator of extracellular matrix-cell communication: Implications in therapy resistance J Gonzalez-Molina, L Moyano-Galceran, A Single, O Gultekin, S Alsalhi, ... Seminars in Cancer Biology 86, 224-236, 2022 | 31 | 2022 |
| Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model L Tanner, AB Single, RKV Bhongir, M Heusel, T Mohanty, CAQ Karlsson, ... Nature communications 14 (1), 643, 2023 | 21 | 2023 |
| A high-throughput screen to identify novel synthetic lethal compounds for the treatment of E-cadherin-deficient cells H Beetham, A Chen, BJ Telford, A Single, KE Jarman, K Lackovic, ... Scientific Reports 9 (1), 12511, 2019 | 15 | 2019 |
| Citrullination of extracellular histone H3. 1 reduces antibacterial activity and exacerbates its proteolytic degradation L Tanner, RKV Bhongir, CAQ Karlsson, S Le, JK Ljungberg, P Andersson, ... Journal of Cystic Fibrosis 20 (2), 346-355, 2021 | 12 | 2021 |
| Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis L Tanner, AB Single, RKV Bonghir, R Oomen, O Wallner, T Helleday, ... bioRxiv, 2021.02. 27.433075, 2021 | 3 | 2021 |
| Synergistic synthetic lethal drug combinations for E-cadherin-deficient cancers AB Single University of Otago, 2018 | 3 | 2018 |
| Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis L Tanner, J Bergwik, AB Single, RKV Bhongir, JS Erjefält, A Egesten Frontiers in Pharmacology 13, 899469, 2022 | 2 | 2022 |
| Citrullination of Extracellular Histone H3. 1 Reduces Antibacterial Activity and Enhances Proteolytic Degradation by Neutrophil Elastase L Tanner, C Andersson, J Ljungberg, RKV Bhongir, A Egesten, AB Single D70. REVISITING LUNG INFECTION AND INFLAMMATORY AXES, A7446-A7446, 2020 | 1 | 2020 |
| LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model A Díez-Sánchez, HT Lindholm, PM Vornewald, J Ostrop, R Yao, ... Nature Communications 15 (1), 3412, 2024 | | 2024 |
| OGG1 Inhibition Attenuates Bleomycin-Induced Lung Injury and Inflammation AB Single, L Tanner, RKV Bhongir, O Wallner, K Sanjiv, T Pham, A Rasti, ... D35. LUNG INJURY AND REPAIR: CELLULAR MECHANISMS, A6532-A6532, 2020 | | 2020 |
| Abstract B41: Statins show synthetic lethality in E-cadherin-deficient cells and are synergistic with SRC and HDAC inhibitors A Single, A Chen, B Telford, H Beetham, P Guilford Clinical Cancer Research 23 (1_Supplement), B41-B41, 2017 | | 2017 |
| Abstract B04: Synthetic lethal targeting of E-cadherin-deficient cancers PJ Guilford, A Chen, B Telford, A Single, H Beetham, T Godwin Clinical Cancer Research 23 (1_Supplement), B04-B04, 2017 | | 2017 |
| Synthetic lethal approaches targeting E-cadherin-deficient cancers A Chen, BJ Telford, A Single, H Beetham, KJ Simpson, P Guilford Cancer Research 76 (14_Supplement), 3814-3814, 2016 | | 2016 |
