MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells L Sinkkonen, T Hugenschmidt, P Berninger, D Gaidatzis, F Mohn, ... Nature structural & molecular biology 15 (3), 259-267, 2008 | 601 | 2008 |
The human peroxisome proliferator-activated receptor δ gene is a primary target of 1α, 25-dihydroxyvitamin D3 and its nuclear receptor TW Dunlop, S Väisänen, C Frank, F Molnár, L Sinkkonen, C Carlberg Journal of molecular biology 349 (2), 248-260, 2005 | 319 | 2005 |
Neurodegeneration by activation of the microglial complement–phagosome pathway LG Bodea, Y Wang, B Linnartz-Gerlach, J Kopatz, L Sinkkonen, ... Journal of Neuroscience 34 (25), 8546-8556, 2014 | 228 | 2014 |
Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1α, 25-dihydroxyvitamin D3 S Väisänen, TW Dunlop, L Sinkkonen, C Frank, C Carlberg Journal of molecular biology 350 (1), 65-77, 2005 | 168 | 2005 |
Gene-pair expression signatures reveal lineage control M Heinäniemi, M Nykter, R Kramer, A Wienecke-Baldacchino, ... Nature methods 10 (6), 577-583, 2013 | 140 | 2013 |
Dicer is associated with ribosomal DNA chromatin in mammalian cells L Sinkkonen, T Hugenschmidt, W Filipowicz, P Svoboda PloS one 5 (8), e12175, 2010 | 101 | 2010 |
Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes E John, A Wienecke-Baldacchino, M Liivrand, M Heinäniemi, C Carlberg, ... Nucleic acids research 40 (10), 4446-4460, 2012 | 87 | 2012 |
TREM2 triggers microglial density and age‐related neuronal loss B Linnartz‐Gerlach, LG Bodea, C Klaus, A Ginolhac, R Halder, ... Glia 67 (3), 539-550, 2019 | 85 | 2019 |
Regulation of the human cyclin C gene via multiple vitamin D 3 -responsive regions in its promoter L Sinkkonen, M Malinen, K Saavalainen, S Väisänen, C Carlberg Nucleic acids research 33 (8), 2440-2451, 2005 | 74 | 2005 |
Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network M Galhardo, L Sinkkonen, P Berninger, J Lin, T Sauter, M Heinäniemi Nucleic acids research 42 (3), 1474-1496, 2014 | 66 | 2014 |
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture M Bouvy-Liivrand, A Hernández de Sande, P Pölönen, J Mehtonen, ... Nucleic acids research 45 (17), 9837-9849, 2017 | 55 | 2017 |
Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network MP Pacheco, E John, T Kaoma, M Heinäniemi, N Nicot, L Vallar, JL Bueb, ... BMC genomics 16, 1-24, 2015 | 51 | 2015 |
Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites C Carlberg, TW Dunlop, A Saramäki, L Sinkkonen, M Matilainen, ... The Journal of steroid biochemistry and molecular biology 103 (3-5), 338-343, 2007 | 40 | 2007 |
Missing heritability in Parkinson’s disease: the emerging role of non-coding genetic variation J Ohnmacht, P May, L Sinkkonen, R Krüger Journal of Neural Transmission 127, 729-748, 2020 | 39 | 2020 |
Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis M Lahnalampi, M Heinäniemi, L Sinkkonen, M Wabitsch, C Carlberg PLoS One 5 (9), e12991, 2010 | 36 | 2010 |
Combinatorial regulation of lipoprotein lipase by microRNAs during mouse adipogenesis M Bouvy-Liivrand, M Heinäniemi, E John, JG Schneider, T Sauter, ... RNA biology 11 (1), 76-91, 2014 | 35 | 2014 |
Normal and pathological NRF2 signalling in the central nervous system T Heurtaux, DS Bouvier, A Benani, S Helgueta Romero, ... Antioxidants 11 (8), 1426, 2022 | 27 | 2022 |
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 J Walter, S Bolognin, SK Poovathingal, S Magni, D Gerard, PMA Antony, ... Cell Reports 37 (3), 2021 | 26 | 2021 |
Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice C Klaus, JN Hansen, A Ginolhac, D Gérard, VS Gnanapragassam, ... Neurobiology of Aging 88, 91-107, 2020 | 25 | 2020 |
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients SL Nickels, J Walter, S Bolognin, D Gérard, C Jaeger, X Qing, J Tisserand, ... Parkinsonism & Related Disorders 67, 48-55, 2019 | 20 | 2019 |