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Hua Zhang
Hua Zhang
University of Pittsburgh School of Medicine
Verified email at pitt.edu
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Cited by
Year
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
Cancer discovery 8 (2), 216-233, 2018
5812018
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ...
Cancer discovery 8 (2), 196-215, 2018
4362018
Clinical characteristics and outcomes of COVID-19–infected cancer patients: a systematic review and meta-analysis
H Zhang, H Han, T He, KE Labbe, AV Hernandez, H Chen, V Velcheti, ...
JNCI: Journal of the National Cancer Institute 113 (4), 371-380, 2021
2152021
CDK7 inhibition potentiates genome instability triggering anti-tumor immunity in small cell lung cancer
H Zhang, CL Christensen, R Dries, MG Oser, J Deng, B Diskin, F Li, Y Pan, ...
Cancer cell 37 (1), 37-54. e9, 2020
1702020
Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer
G Giamas, A Filipović, J Jacob, W Messier, H Zhang, D Yang, W Zhang, ...
Nature medicine 17 (6), 715-719, 2011
1512011
New approaches to SCLC therapy: from the laboratory to the clinic
JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ...
Journal of Thoracic Oncology 15 (4), 520-540, 2020
1462020
In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma
F Li, Q Huang, TA Luster, H Hu, H Zhang, WL Ng, A Khodadadi-Jamayran, ...
Cancer discovery 10 (2), 270-287, 2020
1422020
The regulatory roles of phosphatases in cancer
J Stebbing, LC Lit, H Zhang, RS Darrington, O Melaiu, B Rudraraju, ...
Oncogene 33 (8), 939-953, 2014
1092014
SARS-CoV-2 spike protein interacts with multiple innate immune receptors
C Gao, J Zeng, N Jia, K Stavenhagen, Y Matsumoto, H Zhang, J Li, ...
BioRxiv, 2020
972020
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis
MG Oser, AH Sabet, W Gao, AA Chakraborty, AC Schinzel, RB Jennings, ...
Genes & development 33 (23-24), 1718-1738, 2019
802019
Impact of PD-L1 expression, driver mutations and clinical characteristics on survival after anti-PD-1/PD-L1 immunotherapy versus chemotherapy in non-small-cell lung cancer: a …
Q Huang, H Zhang, J Hai, MA Socinski, E Lim, H Chen, J Stebbing
Oncoimmunology 7 (12), e1396403, 2018
692018
Generation of genetically engineered mouse lung organoid models for squamous cell lung cancers allows for the study of combinatorial immunotherapy
J Hai, H Zhang, J Zhou, Z Wu, T Chen, E Papadopoulos, CM Dowling, ...
Clinical Cancer Research 26 (13), 3431-3442, 2020
502020
The role of pseudokinases in cancer
H Zhang, A Photiou, A Grothey, J Stebbing, G Giamas
Cellular signalling 24 (6), 1173-1184, 2012
492012
The kinase LMTK3 promotes invasion in breast cancer through GRB2-mediated induction of integrin β1
Y Xu, H Zhang, LC Lit, A Grothey, M Athanasiadou, M Kiritsi, Y Lombardo, ...
Science signaling 7 (330), ra58-ra58, 2014
472014
The dual function of KSR1: a pseudokinase and beyond
H Zhang, CY Koo, J Stebbing, G Giamas
Biochemical Society transactions 41 (4), 1078-1082, 2013
402013
NK cells mediate synergistic antitumor effects of combined inhibition of HDAC6 and BET in a SCLC preclinical model
Y Liu, Y Li, S Liu, DO Adeegbe, CL Christensen, MM Quinn, R Dries, ...
Cancer research 78 (13), 3709-3717, 2018
392018
Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer
CM Dowling, KER Hollinshead, A Di Grande, J Pritchard, H Zhang, ...
Science advances 7 (3), eabc4897, 2021
382021
Integrated analysis of multiple receptor tyrosine kinases identifies Axl as a therapeutic target and mediator of resistance to sorafenib in hepatocellular carcinoma
DJ Pinato, MW Brown, S Trousil, EO Aboagye, J Beaumont, H Zhang, ...
British journal of cancer 120 (5), 512-521, 2019
372019
Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib
H Han, S Li, T Chen, M Fitzgerald, S Liu, C Peng, KH Tang, S Cao, ...
Cancer research 81 (20), 5311-5324, 2021
362021
Recent advances in preclinical models for lung squamous cell carcinoma
Y Pan, H Han, KE Labbe, H Zhang, KK Wong
Oncogene 40 (16), 2817-2829, 2021
312021
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